Results for Environment
40,772 grants found
Showing 37,181 – 37,200 of 40,772 grants for "Environment"
Identifying Patient Subgroups That Are Most Likely To Benefit From Medications Used To Treat Alcohol Use Disorder
PROJECT SUMMARY/ABSTRACT The objective of this K01 award is to provide Dr. Joshua Wallach, an Assistant Professor of Epidemiology at the Yale School of Public Health, with the prot...
TGF-Beta Regulates CFTR-Mediated Airway Smooth Muscle Dysfunction
PROJECT SUMMARY/ABSTRACT Cystic fibrosis (CF) is a lethal genetic disorder characterized by progressive lung disease and airway obstruction. CF is caused by mutations in the CF tra...
TGF-Beta Regulates CFTR-Mediated Airway Smooth Muscle Dysfunction
PROJECT SUMMARY/ABSTRACT Cystic fibrosis (CF) is a lethal genetic disorder characterized by progressive lung disease and airway obstruction. CF is caused by mutations in the CF tra...
Nuclear Organization and Function
PROJECT SUMMARY. Proper regulation of gene expression is essential for cell differentiation and homeostasis. Most of our understanding of the mechanisms that control the transcript...
Identifying patient subgroups that are most likely to benefit from medications used to treat alcohol use disorder
PROJECT SUMMARY/ABSTRACT The objective of this K01 award is to provide Dr. Joshua Wallach, an Assistant Professor of Epidemiology at the Yale School of Public Health, with the prot...
Identifying Patient Subgroups That Are Most Likely To Benefit From Medications Used To Treat Alcohol Use Disorder
PROJECT SUMMARY/ABSTRACT The objective of this K01 award is to provide Dr.Joshua Wallach, an Assistant Professor of Epidemiology at the Yale School of Public Health, with the prote...
RUI: Regulation of the plant endocycle by F-BOX STRESS INDUCED 1
A defining, and perpetually intriguing, feature of plants is their ability to thrive in highly dynamic and oftentimes stressful environments. However, many molecular mechanisms use...
Planning a Shared Autonomous Vehicle Mobility Pilot for Linking Affordable Housing and Jobs
Low-mid income residents living in affordable housing areas of a city are often faced with problems in accessing jobs or other locations of opportunity due to limited mobility choi...
Back to the Future: Archiving Residential Children's Homes (ARCH) in Scotland and Germany
There has been increasing interest in the ways in which children in state care have their lives recorded. This has occurred amid growing criticism of how they are supported to acce...
Improving the performance of an AI-enabled clinical decision support tool for detecting suicidal risk and other mental health concerns
PROJECT SUMMARY?Clarigent Health is refining an AI-enabled clinical decision support tool that uses linguistic and acoustic patterns in recorded patient interviews to identify pati...
The Progeria Research Foundation 10th International Scientific Workshop, "Researching Possibilities, ExTENding Lives
Overview: Hutchinson-Gilford progeria syndrome (HGPS or Progeria) is a rare, fatal segmental premature aging disease caused by a splice site mutation in the LMNA gene.Children with...
Impact of ANCA Type and Rituximab vs. Cyclophosphamide on Cardiovascular Risk, Mortality, and Quality-Adjusted Life Years inANCA-Associated Vasculitis
Candidate: Zachary S.Wallace, MD is an Instructor in Medicine at Harvard Medical School (HMS) and an Assistant in Medicine in the Rheumatology Unit at Massachusetts General Hospita...
Understanding biased agonism in receptor tyrosine kinases to devise new modalities for their targeting in cancer
PROJECT SUMMARY/ABSTRACT This project takes a unique dynamic view of signaling by receptor tyrosine kinases (RTKs), testing the hypothesis that signaling specificity is kinetically...
Understanding biased agonism in receptor tyrosine kinases to devise new modalities for their targeting in cancer
PROJECT SUMMARY/ABSTRACT This project takes a unique dynamic view of signaling by receptor tyrosine kinases (RTKs), testing the hypothesis that signaling specificity is kinetically...
Chromatin Organization in Glioma Initiation
Project Summary Glioma is the most common primary brain tumor and represents a disproportionate percentage of cancer fatalities in relation to its incidence.In the last decade, it...
Chromatin Organization in Glioma Initiation
Project SummaryGlioma is the most common primary brain tumor and represents a disproportionate percentage of cancer fatalities in relationto its incidence. In the last decade, it h...
Chromatin Organization in Glioma Initiation
Project SummaryGlioma is the most common primary brain tumor and represents a disproportionate percentage of cancer fatalities in relationto its incidence. In the last decade, it h...
Live Imaging of Immunity to M. tuberculosis
Project Summary Tuberculosis (TB), caused by the bacterium, Mycobacterium tuberculosis, kills more humans every year than does any other infectious disease, including HIV. Among th...
The Striatum and Hippocampus: "Hubs" of White Matter Connections in Parkinson's Disease Cognitive Decline
Due to an aging population and increased lifespan, dementia is an increasing clinical and public health issue.The most common and well-known cause is Alzheimer’s disease (AD), but...
SitS: Collaborative Research: Understand and forecast long-term variations of in-situ geophysical and geomechanical characteristics of degrading permafrost in the Arctic
Climate change is resulting in warming of the permafrost across the Arctic and sub-Arctic, which results in changes in the geological and mechanical properties of soils. Quantifyin...