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Food Responsive Sensor for Colorimetric Observation
Enhancing food safety and reducing waste are global challenges, especially with the rise in food consumption and distribution. Food spoilage is a key component of these challenges....
Tight junctions and tissue mechanics as sensors and executers of heart regeneration
One of the most fascinating aspects of salamander regeneration is the level of precision at which restoration of complex structures occurs. How the recovery of form and function is...
Collective Regulation of Cell Decisions
Developing systems show an unmatched complexity due to an entangled regulation across different levels of organization. Errors in this regulation often lead to tissue and organ mal...
The Scale Revolution in Physics: Historical and Philosophical Perspectives
The ideal of a final theory has shaped much of modern physics and its philosophical interpretations. Physicists have used it as a blueprint to construct theories of space, time, ma...
Precise, Rapid and Scalable Proteomics Solutions for Archaeology, Ecology, Wildlife Forensics and Food-chain Authentication
Taxonomic identification of tiny organic samples using proteins (proteomics) has major, but only partially realised, potential in archaeology, ecology, wildlife forensics and food-...
The Bacillus subtilis circadian clock: from molecules to mutualism
Circadian clocks are biological timekeepers. They structure processes - from molecular pathways to behavioural attributes - over the 24h day. They are pervasive in eukaryotes yet r...
Deciphering context-dependent roles of oncogenic gene fusions in vivo
Sarcomas are an extremely heterogeneous group of mesenchymal cancers, many of which remain lethal despite decades of clinical trials. A unifying characteristic in pediatric sarcoma...
Chiral bUilding Blocks with bRidged or Caged polyclic structures
Drug candidates should have a higher proportion of Csp3 over Csp2 and Csp and a greater number of stereogenic centers. That is essentially the message of F. Lovering et al. in thei...
Uncovering New Worlds: Enhancing Optical Interferometry to detect reflected light exoplanet
The project's objective is to develop PLANETES, a pioneering ground-based interferometric system, engineered to transform the study of exoplanet atmospheres through high-contrast o...
Wafer scale dielectrics on two-dimensional semiconductors for high-performance field effect transistors
The current semiconductor market – dominated by field effect transistors (FETs) is valued at $607.40 billion per year (projected to reach $980.80 billion by 2029). A significant po...
Superconducting Parametric Amplifier Receiver Technology for Astronomy and Fundamental Physics Experiments
The emerging technology of superconducting parametric amplifiers (SPAs) can achieve quantum-limited sensitivity over a broad bandwidth by utilizing the wave-mixing mechanism in a n...
Tracing the origin of clonal pathogenesis
Epithelial cancers are thought to evolve through a competitive process of mutation and selection in which the serial acquisition of oncogenic mutations confers an increasing fitnes...
Air shower interferometry to advance astroparticle physics
The universe hosts a population of subatomic particles with astonishingly high kinetic energies, so-called cosmic rays. Where and how they obtain this energy is unknown. These part...
Genomic Signatures of Selection In Structured Populations: Detecting Temporal Shifts and Local Adaptation
Demographic and selective processes jointly influence the distribution of species in space and time. However, their interaction remains poorly studied despite its potential to form...
PRESERT: linking prefrontal cortex, serotonin transporter and social cognition.
Neuropsychiatric and neurodevelopmental disorders are a heterogeneous group of mental diseases affecting about 1 billion people worldwide. Common alterations are in the cognitive a...
Deep representational learning of the evolutionary DNA code in the vertebrate pallium
Vertebrate genomes consist of tens of thousands of genes and yet they produce only a limited number of stable cell types. Our understanding of how cell types are encoded in the gen...
Cryo-ET of Alphavirus Replication Complex (CryoARC)
Positive-sense single-stranded RNA (+ssRNA) viruses replicate their genomes in membrane-bound, virus-induced replication complexes (RCs). A major genus of +ssRNA viruses are the Al...
Deciphering the newly discovered branchial cavity immune surveillance system to protect fish against infectious diseases in aquaculture.
The sustainability of aquaculture, an important food source for human, is severely challenged by infectious diseases. Unfortunately, the development of new therapies and vaccines i...
Expanding the genome editing toolbox by rational reprogramming of tyrosine recombinase DNA specificities
Gene therapies aim to cure genetic diseases by modifying the DNA blueprint. An ideal gene therapy should be durable, safe, and efficient, which often requires integration of large...
Data-driven market power in the production of addiction
The DATA-ADDICT project studies data-driven market power in the production of addiction. It focuses on online gambling as a key empirical example of a highly addictive, digital, an...