Results for Environment
40,772 grants found
Showing 36,901 – 36,920 of 40,772 grants for "Environment"
Novel animal models to dissect how lung macrophages contribute to SARS-CoV2 alveolar pathology and respiratory failure
This application seeks support for a research-emphasis veterinarian embarking on an independent career as a translational veterinarian-scientist. The applicant proposes to study ma...
Retrograde transmission of pathogenic TDP-43 to the CNS
Project Summary/Abstract TDP-43 is a common protein found aggregated in multiple neurodegenerative diseases and myopathies. TDP- 43 is a ubiquitously expressed RNA-binding protein...
Mechanisms and functions of fatty acid oxidation in T cell differentiation
Project Summary/Abstract Through this K22 Career Development Award proposal, I seek further mentored research training while developing career skills to facilitate a successful tra...
Myocardial-associated B lymphocytes and inflammatory injury
Project Summary/Abstract: Heart failure is a debilitating disease. A growing body of evidence indicates that inflammation plays an important role in the development and progression...
2022 Thalamocortical Interactions GRC and GRS
PROJECT SUMMARY The Gordon Research Conference (GRC) on “Thalamocortical Interactions: Thalamic Architecture, Dynamics, and Function in Health and Disease” will be held from Februa...
SCC-IRG Track 2: Digital Twin City for Age-friendly Communities - Crowd-biosensing of Environmental Distress for Older Adults
Older adults bear a high risk of multiple chronic diseases and face high healthcare cost expenditures. Physical activity such as walking is considered the most effective preventive...
Synergistic Triple Modality PET/SPECT/CT Reconstruction for Early Detection and Treatment of Cancer
1) Brief description of the context of the research including potential impactPET/CT & SPECT/CT imaging is used widely in the diagnosis of cancer, inflammation, infection,...
Applying Student Knowledge for Success in Cybersecurity and Data Science
This project will contribute to the national need for well-educated scientists, mathematicians, engineers, and technicians by supporting the retention and graduation of high-achiev...
Glacial-Interglacial Changes in Oxygen Minimum Zones Using Deep-Dwelling, Low-Oxygen Planktic Foraminifera
Oxygen minimum zones (OMZs) are naturally occurring regions of low oxygen found across large swaths of the ocean at depths of 100 to 1000 meters below the surface. OMZs play an imp...
Probing the role of a hypothalamic-thalamic-striatal circuit in cue-driven behaviors
PROJECT SUMMARY/ABSTRACT Stimuli (cues) in the environment associated with reward can motivate normal behavior, bringing one in close proximity to valuable resources (e.g. food); b...
Prototype for an online skills-based drug prevention program targeting youth 11-13
PROJECT ABSTRACT Drug prevention programs that migrate to the web are interactive, but mostly fail to engage youth and maximize program exposure.An alternative approach considers g...
Imaging Epigenetic Mechanisms in the Lewy Body Dementias with [11C]Martinostat
Project Summary/Abstract Accumulating evidence suggests that epigenetic changes - functional modifications to the genome that do not change the DNA sequence and that provide a powe...
A multimethod examination of individual and environmental contributors to racial disparities in marijuana use
Project Summary Significance: Black relative to White young adults engage in heavier marijuana (MJ) use and are more likely to experience cannabis use disorder.The reasons for thes...
Structure-function changes in the mitochondrial interactome with age
ABSTRACT Sarcopenia, the loss of skeletal muscle quantity and quality with age, is a significant and growing public health problem due to the associated loss of independence and fr...
Health and Functioning in New Midlife Adults: Understanding the Role of Alcohol Use, Social Environments, and Preventive Intervention over the Life Course
ABSTRACT Significant transitions at midlife can be positive for some, but many also experience emotional challenges, physical health declines, and high stress in adapting to new so...
Characterizing Brain Activation and Postural Response During Concurrent Cognitive Tasks in the Presence of Optic Flow Stimulation: A Functional Near-Infrared Spectroscopy Study
PROJECT SUMMARY Human postural control involves multiple sensory integrations from visual, somatosensory, and vestibular inputs. Due to a decline in somatosensation and vestibular...
Investigation of brainstem neurons in the regulation of gonadotropin secretion
PROJECT SUMMARY The long-term goal of the proposed research is to determine the neural pathways by which physiological signals regulate gonadotropin secretion, which ultimately det...
RCT to evaluate Bystander-informed See it Stop it (BiSiSi) to Prevent Child Sex Trafficking in Kentucky Middle Schools
The strongest risk factor for child sexual exploitation and trafficking (CSE/T) is a dysfunctional family environment characterized by violence and parental substance use. In Kentu...
Gene regulation and social relationships across the life course in a nonhuman primate model
Project Summary Social support and social integration are some of the most robust predictors of morbidity and mortality identified to date. This relationship arises from increased...
Probing the role of a hypothalamic-thalamic-striatal circuit in cue-driven behaviors
PROJECT SUMMARY/ABSTRACT Stimuli (cues) in the environment associated with reward can motivate normal behavior, bringing one in close proximity to valuable resources (e.g. food); b...