Results for Environment
40,772 grants found
Showing 36,801 – 36,820 of 40,772 grants for "Environment"
Radiosensitization of thyroid cancer by cancer cell specific reduction of gold ions
Abstract. Unlike differentiated thyroid cancer, which has good prognosis, anaplastic thyroid cancer (ATC) remains one of the most aggressive and fatal solid tumors, with a median o...
Using Multi-Omics to Define Regulators and Drivers of Granulomatous Inflammation and Chronic Beryllium Disease
PROJECT SUMMARY/ABSTRACT: The goal of this study is to define cell-specific regulatory networks and key drivers of cellular response to beryllium (Be) that result in the granulomat...
Radiosensitization of thyroid cancer by cancer cell specific reduction of gold ions
Abstract. Unlike differentiated thyroid cancer, which has good prognosis, anaplastic thyroid cancer (ATC) remains one of the most aggressive and fatal solid tumors, with a median o...
Using Multi-Omics to Define Regulators and Drivers of Granulomatous Inflammation and Chronic Beryllium Disease
PROJECT SUMMARY/ABSTRACT: The goal of this study is to define cell-specific regulatory networks and key drivers of cellular response to beryllium (Be) that result in the granulomat...
Neural circuitry underlying emotional abuse and depression in sexual minority youth
PROJECT SUMMARY/ABSTRACT. Emotional abuse (EA) during childhood and adolescence is associated with greater risk and severity of depression. EA is particularly common among sexual m...
The interaction effects of genetic variants, age, diet, sex and mitochondrial copy number on Alzheimer's disease, aging-phenotypes and longevity
As the average age of the population increases, understanding the biology of longevity and diseases of aging is increasingly important. The key role of mitochondria in Alzheimer’s...
Implementation Strategies to Promote Advance Care Planning among Persons Living with ADRD and those with Mild Cognitive Impairment in Outpatient Primary Care Practices
Many community-dwelling persons living with Alzheimer’s disease and related dementias (AD/ADRD) and those with mild cognitive impairment (MCI) receive aggressive medical interventi...
Optical probe and instrumentation development for in vivo near-infrared fluorescence imaging of Alzheimer's disease
PROJECT SUMMARY / ABSTRACT The main neuropathological hallmarks of Alzheimer's disease (AD) are the extracellular accumulation of amyloid plaque deposits and intracellular for...
Influence of Genetic Background on Bone Anabolic Response to Mechanical Loading
SUMMARY Osteoporosis is a heritable disease of low bone mass and increased fracture risk. Drugs are available to treat low bone mass, yet they carry risks and have limited indicati...
Anthropogenic land-use changes as a key challenge for honeybee foraging and health
Interest in bees has been growing in recent years, mainly because it has become clear that bees are having an increasingly hard time in the modern world and that humans are respons...
Diet and metabolic factors in the pathogenesis of microscopic colitis
PROJECT SUMMARY/ABSTRACT Microscopic colitis (MC) is a debilitating T-cell-mediated inflammatory disease of the large intestine with an incidence that now rivals that of inflammato...
2022 Photosensory Receptors and Signal Transduction GRC/GRS
Summary At the 2022 Photosensory Receptors and Signal Transduction (PRST) Gordon Research Conference (GRC) to be held in Ventura CA, scientists from all over the world gather to pr...
2022 Musculoskeletal Biology & Bioengineering Gordon Research Conference & Gordon Research Seminar
ABSTRACT Since 1980, the biennial Gordon Research Conference (GRC) on Musculoskeletal Biology and Bioengineering has been the leading forum for the presentation and discussion of n...
Ontogenetic niche of B cells at the CNS borders in homeostasis, aging and autoimmunity
PROJECT SUMMARY B cells have an important pathogenic role in neurological autoimmune disorders, such as multiple sclerosis (MS) and neuropsychiatric systemic lupus erythematosus (N...
Defining the induction and maintenance of myelin-specific tolerance in T cells and B cells using local lymph node depots
PROJECT SUMMARY: During autoimmunity, the body incorrectly identifies “self” molecules as foreign. In multiple sclerosis (MS) attack of myelin in the central nervous system (CNS) l...
The eyes have it: genetic, morphological and functional analysis of differences in compound eyes between Drosophila species
Vision is one of the major sensory systems that helps animals navigate through the environment. There is great variation among the eyes of animals reflecting evolutionary adaptatio...
Wearable Electrostrictive Row-Column Ultrasound Arrays for Longitudinal Echocardiography
Project Summary / Abstract In patients admitted to intensive care units (ICUs) with shock (low blood pressure) that results in both clinical and biochemical evidence of tissue hypo...
HSV1-Induced NMDA Receptor Encephalitis: a De Novo Murine Model of Autoimmune Encephalitis
PROJECT SUMMARY / ABSTRACT: The goals of this Mentored Clinical Scientist Research Career Development Award (K08) are to A) obtain theoretical and hands-on training in 1) rodent ma...
Regulatory Genomics of Ozone Air Pollution Response in Vitro and In Vivo
Project Summary Exposure to the ambient air pollutant ozone (O3) is associated with cardiopulmonary morbidity and mortality, rendering it an important public health issue. Controll...
Wearable Electrostrictive Row-Column Ultrasound Arrays for Longitudinal Echocardiography
Project Summary / Abstract In patients admitted to intensive care units (ICUs) with shock (low blood pressure) that results in both clinical and biochemical evidence of tissue hypo...