Results for Environment
40,772 grants found
Showing 36,721 – 36,740 of 40,772 grants for "Environment"
Targeting Microenvironmental Signals in Myeloid Malignancies
ABSTRACT Interactions of stem cells with their surrounding microenvironment are known to be essential for both normal development, and for sustaining self-renewing adult stem cells...
Psychological and neural mechanisms of social-cognitive deficits in ADHD
Project Summary Attention-deficit hyperactivity disorder (ADHD) is prevalent during early and middle childhood, causing substantial disruptions to everyday life of afflicted childr...
Improving identification of HIV-associated neurocognitive disorder (HAND) in Latin America: A multimodal approach to HAND in Peru
PROJECT SUMMARY This is an application for a K23 award for Dr. Monica M. Diaz, a neurologist at the University of North Carolina at Chapel Hill School of Medicine. Dr. Diaz is esta...
Medical Scientist Training Program
Project Summary The mission of the Harvard/MIT MD-PhD program is to provide an academic and social environment that inculcates in our students the vital importance of rigorous clin...
Ending the HIV Epidemic with Equity: An All-facility Intervention to Reduce Structural Racism and Discrimination and Its Impact on Patient and Healthcare Staff Wellbeing
Project Summary The scope of this study is to engage Ryan White HIV/AIDS Program (RWHAP) funded organizations in Ending the HIV Epidemic (ETHE) areas in the South/East US to co-dev...
Defining the Role of Aire in eTACs and its Contribution to Peripheral Immune Tolerance
PROJECT SUMMARY/ABSTRACT The autoimmune regulator (Aire) gene, a key transcriptional regulator expressed in medullary thymic epithelial cells (mTECs), has been shown to be crucial...
Neural Representation of Learning Social Interactions in Non-Human Primates
Project Summary/Abstract. Visually guided social behavior, specifically cooperation, is one of the primary forces driving the evolution of intelligence and is critical to the healt...
Investigation and application of hydrocarbon-degrading enzymes using cryo-electron microscopy and directed evolution
PROJECT SUMMARY Glycyl radical enzymes (GREs) are a growing superfamily that catalyzes an impressive array of chemical transformations critical to both human health and the environ...
Investigating the mechanism of self-organized cortical patterning in an artificial cortex
The cell cortex underlies essential cellular functions, including cell shape changes that facilitate cell division.Comprised of a meshwork of filamentous actin (F-actin) and the pl...
Brain Structure and Clinical Endpoints in Myotonic Dystrophy Type 2
Project Summary The overall goals of this K23 application are to evaluate the relationship between brain structure and function on cognition and motor performance in myotonic dystr...
Improving identification of HIV-associated neurocognitive disorder (HAND) in Latin America: A multimodal approach to HAND in Peru
PROJECT SUMMARY This is an application for a K23 award for Dr. Monica M. Diaz, a neurologist at the University of North Carolina at Chapel Hill School of Medicine. Dr. Diaz is esta...
Defining the Role of Aire in eTACs and its Contribution to Peripheral Immune Tolerance
PROJECT SUMMARY/ABSTRACT The autoimmune regulator (Aire) gene, a key transcriptional regulator expressed in medullary thymic epithelial cells (mTECs), has been shown to be crucial...
G-RISE at Meharry Medical College
PROJECT SUMMARY/ABSTRACT The Meharry G-RISE program is designed to address the lack of diversity within all facets of the United Stated biomedical research workforce by significant...
CAREER: CAS: Donor-Amplified Catalytic Approaches to Stereocontrolled Biodegradable Polymers
This award is funded in whole or in part under the America Rescue Plan Act of 2021 (Public Law 117-2).With the support of the Chemical Catalysis program in the Division of Chemistr...
Towards Predictive Coarse-grained Models
William Noid of the Pennsylvania State University is supported by an award from the Chemical Theory, Models and Computational Methods program in the Division of Chemistry to develo...
2022 Cytoskeletal Motors Molecular Machines: From Biophysics To Physiology To Disease
The Gordon Research Conference (GRC) and Gordon Research Seminar (GRS) on Cytoskeletal Motors will be held in Dover, VT on July 9-10, and July 10-15, respectively. The GRS is prima...
Advanced planar image reconstruction for targeted alpha therapy
Project Summary Title: Advanced Planar Image Reconstruction for Targeted Alpha Therapy Targeted Alpha Therapy (TAT) based on the alpha-emitting radiopharmaceuticals (AER) has been...
Interrogation and Modulation of the Epigenome after Prenatal Hypoxic Brain Injury
PROJECT SUMMARY Neonatal hypoxic ischemic encephalopathy (HIE), a common brain injury from loss of oxygen and nutrients immediately prior to birth, results in long-term neurologic...
Endoplasmic Reticulum stress and thyroid cell death
ABSTRACT Efficient generation of the thyroid hormone thyroxine (T4) requires the iodination of thyroglobulin (Tg), which is synthesized in the endoplasmic reticulum (ER) and underg...
The Role of Lung Megakaryocytes in Airway Disease after Neonatal Hyperoxia
Former preterm infants are exposed to oxygen (O2) after birth which results in long-term developmental impacts on the lung. Approximately 70% of infants born extremely prematurely...