Results for Environment
40,772 grants found
Showing 36,681 – 36,700 of 40,772 grants for "Environment"
Mechanisms for cellular copper import via secreted cuproproteins
Project Summary: Copper is an essential micronutrient and a required redox-active cofactor for enzymes necessary for eukaryotic respiration, oxidative stress resistance, and the pr...
Mechanisms for cellular copper import via secreted cuproproteins
Project Summary: Copper is an essential micronutrient and a required redox-active cofactor for enzymes necessary for eukaryotic respiration, oxidative stress resistance, and the pr...
Mechanisms for cellular copper import via secreted cuproproteins
Project Summary: Copper is an essential micronutrient and a required redox-active cofactor for enzymes necessary for eukaryotic respiration, oxidative stress resistance, and the pr...
Clinical Practice Network
PROJECT SUMMARY/ABSTRACT The purpose of the Clinical Practice Network (CPN) of the MATCHES Telehealth Research Center is to provide the environment for conducting and evaluating th...
ENACT: Translating Health Informatics Tools to Research and Clinical Decision Making
Several challenges exist in the conduct of EHR-based translational research. First, CTSA hubs vary substantially in their capacity to address challenges in EHR data collection, dat...
Connecting weather-related health risk and climate change projections in relation to rural health disparities
PROJECT SUMMARY The world is already 1.2 oC warmer now than in the second half of the 19th century. The Intergovernmental Panel on Climate Change (IPCC) predicts that we will cross...
Mechanisms for cellular copper import via secreted cuproproteins
Project Summary: Copper is an essential micronutrient and a required redox-active cofactor for enzymes necessary for eukaryotic respiration, oxidative stress resistance, and the pr...
Investigation and application of hydrocarbon-degrading enzymes using cryo-electron microscopy and directed evolution
PROJECT SUMMARY Glycyl radical enzymes (GREs) are a growing superfamily that catalyzes an impressive array of chemical transformations critical to both human health and the environ...
Ending the HIV Epidemic with Equity: An All-facility Intervention to Reduce Structural Racism and Discrimination and Its Impact on Patient and Healthcare Staff Wellbeing
Project Summary The scope of this study is to engage Ryan White HIV/AIDS Program (RWHAP) funded organizations in Ending the HIV Epidemic (ETHE) areas in the South/East US to co-dev...
Improving identification of HIV-associated neurocognitive disorder (HAND) in Latin America: A multimodal approach to HAND in Peru
PROJECT SUMMARY This is an application for a K23 award for Dr. Monica M. Diaz, a neurologist at the University of North Carolina at Chapel Hill School of Medicine. Dr. Diaz is esta...
Targeting Microenvironmental Signals in Myeloid Malignancies
ABSTRACT Interactions of stem cells with their surrounding microenvironment are known to be essential for both normal development, and for sustaining self-renewing adult stem cells...
Dissecting the mechanisms of how MYH7 S2 mutations lead to genetic hypertrophic cardiomyopathy
Familial hypertrophic cardiomyopathy (HCM) is a genetic cardiomyopathy affecting 1 in 500 US adults.1,2 Mutation in myosin heavy chain seven (MYH7), a sarcomeric thick filament pro...
Dissecting the mechanisms of how MYH7 S2 mutations lead to genetic hypertrophic cardiomyopathy
Familial hypertrophic cardiomyopathy (HCM) is a genetic cardiomyopathy affecting 1 in 500 US adults.1,2 Mutation in myosin heavy chain seven (MYH7), a sarcomeric thick filament pro...
Medical Scientist Training Program
Project Summary The mission of the Harvard/MIT MD-PhD program is to provide an academic and social environment that inculcates in our students the vital importance of rigorous clin...
Medical Scientist Training Program
Project Summary The mission of the Harvard/MIT MD-PhD program is to provide an academic and social environment that inculcates in our students the vital importance of rigorous clin...
Defining the Role of Aire in eTACs and its Contribution to Peripheral Immune Tolerance
PROJECT SUMMARY/ABSTRACT The autoimmune regulator (Aire) gene, a key transcriptional regulator expressed in medullary thymic epithelial cells (mTECs), has been shown to be crucial...
Medical Scientist Training Program
Project Summary The mission of the Harvard/MIT MD-PhD program is to provide an academic and social environment that inculcates in our students the vital importance of rigorous clin...
Targeting Microenvironmental Signals in Myeloid Malignancies
ABSTRACT Interactions of stem cells with their surrounding microenvironment are known to be essential for both normal development, and for sustaining self-renewing adult stem cells...
Overcoming the triple threat to diversity in the health science workforce: empowering the next gen.
Interventions to enhance the pool of underrepresented minority (URM) groups in the research workforce, including Blacks or African Americans, Hispanics or Latinos, American Indians...
Efficacy of Precision Text Messaging to Increase Physical Activity in Insufficiently-Active Young Adults
PROJECT SUMMARY Physical activity and weight management are key components of ideal cardiovascular health but many young adults are insufficiently active and gaining weight rapidly...