Results for Environment
40,772 grants found
Showing 36,641 – 36,660 of 40,772 grants for "Environment"
Molecular Dynamics of Glioma Formation and DNA Damage Response by Mutant IDH1
Project Summary/Abstract: Gliomas are the most common primary brain tumors in adults, a subset of which have mutations in the metabolic gene isocitrate dehydrogenase 1 (IDH1). Canc...
Defining the role of seed and soil in peritoneal metastasis evolution
The peritoneum is the third most common site of metastasis in colon cancer. Despite the common occurrence of peritoneal metastasis and its dire prognosis, very little is known abou...
Regulation of Microbial Trafficking to the Thymus in Early Life
Project Summary Early life is a critical period for the proper development of the immune system. As mammalian hosts have co- evolved with their symbiotic bacteria, signals from the...
2024 Cyclic Nucleotide Phosphodiesterases Gordon Research Conference and Gordon Research Seminar
Project Summary/Abstract The 2024 Gordon Research Conference on Cyclic Nucleotide Phosphodiesterases (PDEs) will explore bleeding-edge research driving the field to reconceptualize...
Multiple Stress Pathways and Positive Resources in UF Incidence and Growth
Uterine leiomyomata, also known as uterine fibroids (UF), are benign neoplasms of the uterus and are associated with heavy menstrual bleeding, anemia, pelvic pain, infertility, and...
Collaborative Research: The Role of Tension in the Digestion of Blood Clots
Blood clots form in response to an injury and stop the flow of blood during the wound healing process. The structural scaffold of a blood clot is a mesh of fibers, composed of a bi...
Sex Differences in T cell metabolism
Abstract Sex is an important biological variable as it has dramatic impacts on health and disease. Males have a greater risk for infection and severe outcomes, while females have i...
Evaluating routine clinical decisions in providing primary care for people living with Alzheimer's Disease or Alzheimer's Related Disorders: using electronic health records to provide timely evidence
PROJECT SUMMARY Growing emphasis on the early diagnosis and treatment of Alzheimer’s disease and related dementias (ADRD) increases the demand for providers to make informed care d...
Optimizing an App-based Intervention for Sexual Minoritized Emerging Adults to Reduce Cannabis and Alcohol Co-use
PROJECT SUMMARY/ABSTRACT This K23 award will support Dr. Florimbio, a clinician-scientist with experience researching and treating substance use disorders, in becoming an independe...
Let-7 in Sperm Impacts Offspring Opioid System
The United States is in the midst of an opioid addiction crisis, with exposure rates to opioids estimated to be over 3.3% of the population in 2021 alone. In addition to the devast...
Resubmission - Development and scale-up of Continuous Countercurrent Tangential Chromatography (CCTC) for next generation AAV vector manufacturing (Direct to Phase II)
PROJECT SUMMARY The overall goal of the proposed Direct to Phase II SBIR project is to commercialize Continuous Countercurrent Tangential Chromatography (CCTC) for recombinant AAV...
The role of ATRX in both promoting the establishment of HSV latency and restricting reactivation
The human pathogen, Herpes Simplex Virus (HSV), establishes latency only in neurons and can reactivate to result in the production of infectious virus for transmission to a new hos...
Conference: Society Prioritizes Our Recruitment of Every Scholar (SPORES): A mentoring program with the goal of diversifying, advancing, and promoting future mycologists.
The Society Prioritizes Our Recruitment of Every Scholar (SPORES) workshop, hosted by the Mycological Society of America (MSA), is dedicated to diversifying the field of mycology a...
Reducing disparities in chronic pain with a tailored psychosocial education intervention for an underrepresented population
PROJECT SUMMARY/ABSTRACT Health inequalities in chronic pain exists in the US, with a greater burden of chronic pain and higher rate of misdiagnosis and undertreatment reported in...
Collaborative Research: The Role of Tension in the Digestion of Blood Clots
Blood clots form in response to an injury and stop the flow of blood during the wound healing process. The structural scaffold of a blood clot is a mesh of fibers, composed of a bi...
Evolution and Durability of Human T and B Cell Responses
Human memory B and T cells (Bmem, Tmem) can be found in circulation and residing in lymphoid and non- lymphoid tissues. After infection and vaccination, we can follow antigen (Ag)-...
Triple-enriched metagenomics for robust resistome analysis
Project Summary: Despite reductions in antimicrobial use and implementation of antibiotic stewardship programs, antimicrobial resistant (AMR) pathogens continue to emerge and persi...
EAGER: CET: Non-Equilibrium Plasma-Enhanced Recovery of Lithium and Critical Materials from Produced Water
This EArly-concept Grants for Exploratory Research (EAGER) award is made in response to Dear Colleague Letter 23-109, as part of the NSF-wide Clean Energy Technology initiative. Cr...
CAREER: Early-life social environments drive behavioral and neural mechanisms of development
Individuals are shaped by the experiences they have, particularly those that occur early in life. Although these social effects are well known to occur, social environments are com...
The Role of Hormonal Dysregulation in Systemic Sclerosis
Although patients with systemic sclerosis (SSc) have increased disability, morbidity, and mortality, no current FDA-approved medications for SSc prevent or reverse fibrosis. Our lo...