Results for Environment
40,772 grants found
Showing 36,581 – 36,600 of 40,772 grants for "Environment"
Home-based Digital Technologies: A Translational Approach to Support Aging-in-Place for Rural African-Americans with Alzheimer’s Disease and their Care Partners
PROJECT SUMMARY Candidate and Career Development Plan: This REDI Mentored Entrepreneurial Career Development Award (K01) will support Otis (Shaun) Owens, Ph.D. to establish an inde...
Impact and Utilization of Scalable Functional Assays in Alagille Syndrome
PROJECT SUMMARY/ABSTRACT Uncertainty in our understanding of the functional impact of variation in the human genome has grossly impeded our ability to realize the full potential of...
Identification of trans-regulatory elements controlling MAPT transcription
Project Summary/Abstract Tau, coded for by the gene MAPT, can aggregate in the brain and is associated with many neurodegenerative diseases. Evidence suggests that the level of exp...
Molecular and functional implications of thalamo-striatal synapse regulation in learning and memory
PROJECT ABSTRACT Cognitive changes occur as a normal process of aging and among the most important changes in cognition in normal aging are declines in cognitive flexibility (CF)....
Age, sex, hormonal status, and anti-inflammatory therapy for atherosclerosis
PROJECT SUMMARY. A great accomplishment of modern medicine is the increased lifespan of the population worldwide. Unfortunately, longevity also increased the healthcare burden due...
K23 Resubmission - Impact of adoptive T cell therapy on immunity to SARS-CoV-2 after bone marrow transplant
The overarching goal of this proposal is the development of the candidate into an independent investigator in the field of immune modulatory cell therapy for critically ill childre...
Evaluation of clinical and social factors associated with deficit accumulation trajectories in older survivors with early-stage non-small cell lung cancer
Project Summary Aging involves a gradual clinical decline in cognitive and physical function and often the development of various comorbidities. However, significant life events, s...
MRI Track 1: Acquisition of a Multi-Collector Inductively Coupled Plasma Mass Spectrometer at the University of Utah
This award funds the purchase of a multi-collector inductively coupled plasma mass spectrometer (MC-ICP-MS) at the University of Utah to enable high-precision non-traditional isoto...
Collaborative Research: RAPID: Quantifying the fluvial geomorphic response of the Blue Earth River to a catastrophic avulsive dam failure, Rapidan Dam, Minnesota
After three days (17–20 cm) of rainfall flooded the Blue Earth River, the river avulsed around the western edge of the ~114-year old Rapidan Dam in the early morning of 24 June 202...
A Triad Approach Towards Improved Diagnostics for Maternal and Congenital Syphilis
Project Summary Syphilis is a sexually and vertically transmitted disease caused by Treponema pallidum subspecies pallidum (TPA). While adult syphilis is often asymptomatic and sel...
Neural basis of visual attention in the primate brain
PROJECT SUMMARY Natural scenes are cluttered with multiple objects that compete for neural representation due to limited processing capacity. Mechanisms for selective processing, b...
Digital Strategies to Advance Help-Seeking in Youth at Clinical High Risk for Developing Psychosis
Project Summary Early psychosis intervention is critical to improving clinical and functional outcomes, yet treatment initiation is typically delayed for months to years, resulting...
Developing new biophysical models of choroid fissure closure in zebrafish and foveal pit formation across species
PROJECT SUMMARY The proposed project is a physics and biology collaboration at the University of Northern Colorado (UNC) to model morphogenesis processes in the developing vertebra...
Diagnosis, Treatment, and Monitoring of Polymicrobial Infections in Diabetic Wounds
Project Summary. Research: The proposed research is entitled: Diagnosis, Treatment, and Monitoring of Polymicrobial Infections in Diabetic Wounds. Diabetic wounds are prone to bact...
Leveraging Large Language Models and Machine Learning Algorithms to Assess Depression and Anxiety Symptoms and Risks for Patients with Cardiovascular Disease or Diabetes Mellitus
Project Summary. Depression and anxiety are 2-4 times as likely prevalent among cardiovascular disease (CVD) or diabetes mellitus (DM) patients than among those without CVD or DM....
Validating Mouse Models of Prostatic Hyperplasia
SCIENTIFIC RESEARCH PROJECT: SUMMARY Benign prostatic hyperplasia (BPH) is common, resulting in significant morbidity, billions of dollars in annual medical expenses, and even grea...
Modular Toolbox of Protein and Lipid Hybrid Biomaterials for siRNA Delivery
ABSTRACT/PROJECT DESCRIPTION: Technologies for gene delivery are desperately needed to address a wide array of pathological processes in the various tissues of the body. In particu...
Peer Behavioral Activation Utilization to Address Structural Racism and Discrimination and Improve HIV Outcomes in High-Risk, Substance-Using Populations- PUSH
Background. Substance use continues to be a major driver of HIV acquisition and has been associated with suboptimal ART adherence, treatment interruption, and inability to achieve...
Broad-Color: The Genome Center for the Future of All of Us
ABSTRACT The AU of Us Research Program is building a national biomedical research resource from an historically diverse population to empower and accelerate the understanding, diag...
Collaborative Research: OPUS: Synthesizing multi-decadal and multi-site data to promote understanding of key questions in stochastic demography
The geographical ranges of most species across the Earth are made up of multiple populations (all individuals of that species in a defined area) and these populations often experie...