Results for Environment
40,772 grants found
Showing 36,441 – 36,460 of 40,772 grants for "Environment"
Epigenetic regulators define a dynamic chromatin landscape in NUP98-rearranged leukemia
Project Summary Chromosomal translocations producing oncogenic fusion proteins are common drivers of many types of cancer, including leukemia. Translocations involving the Nucleopo...
Connectome-based neurofeedback of the craving network to reduce food cue-reactivity
PROJECT SUMMARY Overweight (OW) and obesity (OB) are prevalent, unhealthy, and costly. The obesogenic environment is a main contributor to OW and OB, filled with visual cues signal...
Development of a novel tocolytic delivery system to treat preterm labor
Project Summary The following proposal was carefully crafted to foster achievement in both academic and professional development to promote my future goals of becoming a faculty me...
The effects of sleep and iPRGCs on computations in the early visual system
PROJECT SUMMARY/ABSTRACT Vision is an important driver of our evolution and adaptation to different environments. It is a complex process that begins with photoreceptor signal tran...
Skeletal Muscle Stem Cells in Development, Regeneration, and Adaptations
PROJECT SUMMARY This application seeks partial support for the upcoming Society for Muscle Biology (SMB) conference entitled, "Skeletal Muscle Stem Cells in Development, Regen...
Targeting Microenvironmental Signals in Myeloid Malignancies
ABSTRACT Interactions of stem cells with their surrounding microenvironment are known to be essential for both normal development, and for sustaining self-renewing adult stem cells...
Collaborative Research: GEM: Propagation and Dissipation of Electromagnetic Ion Cyclotron Waves in the Magnetosphere and Ionosphere
There are many types of plasma waves in the Earth's magnetosphere. For decades it has been observed that ultra-low frequency electromagnetic ion cyclotron (EMIC) waves in the...
REU Site: Physics and Chemistry Research at The College of Wooster
NON-TECHNICAL SUMMARYSupported by the Division of Materials Research, this REU site in the Physics and Chemistry departments at The College of Wooster involves students as collabor...
Collaborative Research: Improving Upper Division Physics Education and Strengthening Student Research Opportunities at 14 HSIs in California
With support from the Improving Undergraduate STEM Education: Hispanic-Serving Institutions (HSI Program), this Track 2 project aims to improve upper division physics education and...
COBRE in Sex-Based Precision Medicine
Critical to the success of clinical care and translational science is an awareness by clinicians and researchers that diseases are characterized by sex and gender differences in ep...
Probing short and long term consequences of Small and Large Bowel Microbiota Transplants on Host Physiology: Implications for the development of future live biotherapeutics
The intestinal tract is comprised of functionally different regions, each having distinct and highly selected microbiota assembled through evolutionary and ecological drivers to ac...
Dissecting the Role of Germline Genetics in RAS-Driven Cancers
PROJECT SUMMARY/ABSTRACT Most applications of genomics in modern oncology focus on somatic mutations acquired during tumor evolution and selecting drugs to target these tumor-speci...
Cancer Neuroscience - An Emerging Hallmark
ABSTRACT Accelerated understanding of nervous system functions and cancer has led to cancer neuroscience evolving into a new frontier of discovery in cancer biology and therapy. Th...
Wearable Wireless Respiratory Monitoring System that Detects and Predicts Opioid Induced Respiratory Depression
PROJECT SUMMARY FOR THE PREDICATE GRANT. Opioids are the most prescribed drug in US hospitals, and opioid induced respiratory depression (OIRD) is a widespread and life-threatening...
Sensory neuron-skin interaction in health and disease
PROJECT SUMMARY My career goal is to lead an independent research group to investigate the pathology and resolution of pain to solve neuropathic pain problems. To achieve this goal...
Understanding and treating neurogenetic conditions related to the Kennedy pathway
The hereditary spastic paraplegias (HSP)s are a large group of debilitating genetic disorders that lead to lower limb weakness and stiffness (spasticity). Unfortunately, the condit...
Uncovering the Underlying Biophysical Mechanisms of Directed Cell Migration
Matrix-guided cell migration is fundamental to tissue formation, and its dysregulation is crucial in various diseases. Despite this importance, how cells coordinate probing their e...
Identification of a mechanosensor in juxtaglomerular cells for the regulation of renin synthesis and secretion
PROJECT SUMMARY Juxtaglomerular (JG) cells are a cluster of specialized vascular smooth muscle (VSM) cells located in the wall of each afferent arteriole (Af-Art) at the entrance t...
Astrocytes mediate priming of spinal nociceptive circuits
PROJECT SUMMARY/ABSTRACT 9% of children born in the United States are admitted to the neonatal intensive care unit where many experience invasive surgical procedures as part of the...
Latent class analysis as a viable alternative to a panel of clinicians for diagnosis in diagnostic accuracy studies and clinical practice.
Research question Is latent class analysis (LCA) a viable alternative to panel diagnosis in diagnostic accuracy studies and clinical practice? Background Diagnosis is challenging f...