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Results for Environment

40,772 grants found

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Showing 36,16136,180 of 40,772 grants for "Environment"

Completed OTHER RESEARCH-RELATED
The Health Sciences & Technology Academy – Alabama (HSTA-AL)
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Alabama in Tuscaloosa United States 2021 – 2026

Project Summary/Abstract This innovative project will replicate the successful Health Sciences & Technology Academy from West Virginia, with important adaptations for our purpo...

$2.52M
USD
Completed OTHER RESEARCH-RELATED
The Health Sciences & Technology Academy – Alabama (HSTA-AL)
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Alabama in Tuscaloosa United States 2021 – 2026

Project Summary/Abstract This innovative project will replicate the successful Health Sciences & Technology Academy from West Virginia, with important adaptations for our purpo...

$871.8K
USD
Completed NON-SBIR/STTR RPGS
Role of astrocyte-based cholinergic neuromodulation in cognition and in the treatment of cognitive disorders
NATIONAL INSTITUTE OF MENTAL HEALTH Washington University United States 2021 – 2026

ABSTRACT Neurons are viewed as the cellular correlate of cognition and only target of clinical therapeutics, in part because manipulating neurons rapidly and directly alters behavi...

$3.94M
USD
Completed TRAINING, INDIVIDUAL
Development of Faux-Biotics to combat the spread of hospital-acquired antibiotic-resistant infections
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of California At Davis United States 2021 – 2023

Project Summary The CDC considers the escalation of antibiotic resistance to be one of the biggest public health concerns of our time. Antibiotic resistance is a major issue both h...

$698K
USD
Active NON-SBIR/STTR RPGS
State-dependent modulation of retinothalamic axonal boutons
NATIONAL EYE INSTITUTE Beth Israel Deaconess Medical Center United States 2021 – 2026

Summary Perception does not depend on environment alone, but also on brain state. Work from our lab and others show that visual responses to certain features are selectively gated...

$4.4M
USD
Active OTHER RESEARCH-RELATED
Using Induced Pluripotent Stem Cells to Characterize Cystic Fibrosis
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Boston Children'S Hospital United States 2021 – 2026

Project Summary/Abstract This proposal details a 5-yr plan to prepare the candidate, Ruobing Wang, MD, for a career as an independent physician-scientist positioned to impact our u...

$1.68M
USD
Completed NON-SBIR/STTR RPGS
Targeting lysosome/RPE heterogeneity in AMD pathobiology as a novel therapy
NATIONAL EYE INSTITUTE University of Pittsburgh At Pittsburgh United States 2021 – 2025

SUMMARY: Vision loss from age-related macular degeneration (AMD) is a major, expanding problem due to the aging population. While treatment is available for intermediate AMD and th...

$6.08M
USD
Completed NON-SBIR/STTR RPGS
Targeting lysosome/RPE heterogeneity in AMD pathobiology as a novel therapy
NATIONAL EYE INSTITUTE University of Pittsburgh At Pittsburgh United States 2021 – 2025

SUMMARY: Vision loss from age-related macular degeneration (AMD) is a major, expanding problem due to the aging population. While treatment is available for intermediate AMD and th...

$6.02M
USD
Active NON-SBIR/STTR RPGS
State-dependent modulation of retinothalamic axonal boutons
NATIONAL EYE INSTITUTE Beth Israel Deaconess Medical Center United States 2021 – 2026

Summary Perception does not depend on environment alone, but also on brain state. Work from our lab and others show that visual responses to certain features are selectively gated...

$4.4M
USD
Active OTHER RESEARCH-RELATED
Using Induced Pluripotent Stem Cells to Characterize Cystic Fibrosis
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Boston Children'S Hospital United States 2021 – 2026

Project Summary/Abstract This proposal details a 5-yr plan to prepare the candidate, Ruobing Wang, MD, for a career as an independent physician-scientist positioned to impact our u...

$1.68M
USD
Active NON-SBIR/STTR RPGS
Evaluating the Role of Sleep in the Development of Intensive Care Unit Delirium
NATIONAL INSTITUTE OF NURSING RESEARCH Vanderbilt University United States 2021 – 2026

PROJECT SUMMARY More than one third of patients in the intensive care unit (ICU) develop ICU delirium, an acute, fluctuating form of cognitive dysfunction that is associated with i...

$2.44M
USD
Completed OTHER RESEARCH-RELATED
2021 Central Nervous System Injury and Repair Gordon Research Conference and Gordon Research Seminar
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... Gordon Research Conferences United States 2021 – 2022

The goal of this new Gordon Research Conference (GRC) series, entitled ?Central Nervous System Injury and Repair?, together with its accompanying Gordon Research Seminar (GRS), is...

$120K
USD
Completed TRAINING, INDIVIDUAL
Racial/Ethnic Differences in Palliative Care Services and Potentially Avoidable Hospitalizations at End-of-Life in Nursing Homes Nationwide
NATIONAL INSTITUTE OF NURSING RESEARCH Columbia University Health Sciences United States 2021 – 2022

On any day, approximately 1.6 million Americans live in the nation?s nursing homes (NHs) and 90% of the residents are ? 65-years old.In the last two decades, there has been an incr...

$460.4K
USD
Active TRAINING, INSTITUTIONAL
Predoctoral Training in Pharmacological Sciences
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Weill Medical Coll of Cornell Univ United States 2021 – 2026

Project Summary This is a ?new?T32 grant application seeking support for Training in the Pharmacological Sciences (TIPS) at the Weill Cornell Graduate School (WCGS).If awarded, tha...

$3.9M
USD
Completed TRAINING, INDIVIDUAL
Forkhead factor regulation in oral viral infection
NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEAR... University of Florida United States 2021 – 2024

The oral cavity is the initial site of infection for many pathogens, including viruses.Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic virus that is shed in sal...

$445.8K
USD
Active OTHERS
Microbiomal Mediators of TL1A-induced-Fibrosis
Veterans Affairs Va Greater Los Angeles Healthcare System United States 2021 – 2026

ABSTRACT Inflammatory Bowel Disease (IBD) results from a series of complex interactions between susceptibility and severity genes, the environment and the mucosal immune system, pr...

Completed NON-SBIR/STTR RPGS
The terminal steps of cortisol and aldosterone biosynthesis
Veterans Affairs Veterans Health Administration United States 2021 – 2025

Excess aldosterone and cortisol production from the human adrenal cortex commonly contributes to hypertension, heart failure, obesity, glucose intolerance, and low bone mass.Cytoch...

Completed OTHER RESEARCH-RELATED
Unraveling the PTEN Interactome: Modeling Structural and Functional Dynamic Network Architecture for Therapeutic Modulation in Cancer and Autism
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Cleveland Clinic Lerner Com-Cwru United States 2021 – 2023

PROJECT SUMMARY/ABSTRACT Unraveling the PTEN Interactome: Modeling Structural and Functional Dynamic Network Architecture for Therapeutic Modulation in Cancer and Autism The candid...

$1M
USD
Active OTHER RESEARCH-RELATED
Defining PARP Inhibitor Response and Resistance in Prostate Cancer
NATIONAL CANCER INSTITUTE University of California At Davis United States 2021 – 2026

PROJECT SUMMARY/ABSTRACT The objective of this K01 award is to promote the development of Dr. Alan Lombard into an independent prostate cancer researcher. The proposed project will...

$1.67M
USD
Active OTHER RESEARCH-RELATED
Inducing Mirth to Improve Memory in Depression
NATIONAL INSTITUTE OF MENTAL HEALTH Mclean Hospital United States 2021 – 2026

Major Depressive Disorder (MDD) impacts an estimated 17.3 million adult Americans per year, which places an enormous burden on the affected individuals as well as our healthcare sy...

$1.74M
USD