Results for Environment
40,772 grants found
Showing 36,141 – 36,160 of 40,772 grants for "Environment"
Investigating the Role of GDE2 in Neuronal Mitotic Inhibition and Nuclear Pore Complex Defects
Project Summary / Abstract Alzheimer's disease (AD) and related diseases (ADRDs) are the leading cause of dementia, affecting millions of people each year. Despite being such...
The Biology of Motile Cilia
Cilia are microtubule-based cellular extensions that play key roles in sensing the extracellular environment, processing developmental signals and generating propulsive force and f...
Investigating the Role of GDE2 in Neuronal Mitotic Inhibition and Nuclear Pore Complex Defects
Project Summary / Abstract Alzheimer's disease (AD) and related diseases (ADRDs) are the leading cause of dementia, affecting millions of people each year.Despite being such a...
Investigating the Role of GDE2 in Neuronal Mitotic Inhibition and Nuclear Pore Complex Defects
Project Summary / Abstract Alzheimer's disease (AD) and related diseases (ADRDs) are the leading cause of dementia, affecting millions of people each year. Despite being such...
Developmental Origins of Neurotoxicity of the PFAS GenX
PROJECT SUMMARY / ABSTRACT Per- and polyfluoroalkyl substances (PFAS) are synthetic fluorine-containing compounds that are present in many applications due to their non-stick and s...
Developmental Origins of Neurotoxicity of the PFAS GenX
PROJECT SUMMARY / ABSTRACT Per- and polyfluoroalkyl substances (PFAS) are synthetic fluorine-containing compounds that are present in many applications due to their non-stick and s...
Neural circuit mechanisms controlling seizures
Temporal lobe epilepsy (TLE) is the most common form of epilepsy in adults and is associated with significant cognitive decline.In over 40% of TLE cases, seizures are not controlle...
Genetics of oxycodone intake in a hybrid rat diversity panel.
The steady rise in prescription opioids such as oxycodone has led to widespread abuse and deaths in the US. importance of drug pharmacokinetics in determining abuse potential, we h...
Diet Related Inflammation and Kidney Function Decline in Racial/Ethnic Minorities
PROJECT SUMMARY/ ABSTRACT: The primary purpose of this proposal is to provide Tanya Johns, MD, MHS, a clinical investigator in the Department of Medicine (Division of Nephrology) a...
Diet Related Inflammation and Kidney Function Decline in Racial/Ethnic Minorities
PROJECT SUMMARY/ ABSTRACT: The primary purpose of this proposal is to provide Tanya Johns, MD, MHS, a clinical investigator in the Department of Medicine (Division of Nephrology) a...
Workshop on Devices-to-Systems for In-Memory Computing, being held Virtual at the University of Cincinnati, Cincinnati, Ohio, May 11-12, 2021.
In-memory computing architectures are envisioned to be enablers for implementing data-driven algorithms using Machine Learning and Artificial Intelligence for applications, such as...
Diet Related Inflammation and Kidney Function Decline in Racial/Ethnic Minorities
PROJECT SUMMARY/ ABSTRACT: The primary purpose of this proposal is to provide Tanya Johns, MD, MHS, a clinical investigator in the Department of Medicine (Division of Nephrology) a...
Molecular impediments to fate-specifying pioneer factor activity during development
Project Summary/Abstract Transcription factors act as specifying agents of cell differentiation during development by binding to DNA enhancer sequences and activating them to contr...
Molecular impediments to fate-specifying pioneer factor activity during development
Project Summary/Abstract Transcription factors act as specifying agents of cell differentiation during development by binding to DNA enhancer sequences and activating them to contr...
Molecular impediments to fate-specifying pioneer factor activity during development
Project Summary/Abstract Transcription factors act as specifying agents of cell differentiation during development by binding to DNA enhancer sequences and activating them to contr...
Molecular impediments to fate-specifying pioneer factor activity during development
Project Summary/Abstract Transcription factors act as specifying agents of cell differentiation during development by binding to DNA enhancer sequences and activating them to contr...
Single-molecule Measurements of Membrane-protein Folding and Ligand-Interaction Energetics in Bacteriorhodopsin and the Diabetes-insipidus-involved Vasopressin Receptor 2
Project Summary/Abstract Human arginine vasopressin receptor 2 (AVPR2) is an ?-helical membrane protein expressed in the collecting ducts of the kidneys involved in regulating urin...
Targeting lysosome/RPE heterogeneity in AMD pathobiology as a novel therapy
SUMMARY: Vision loss from age-related macular degeneration (AMD) is a major, expanding problem due to the aging population. While treatment is available for intermediate AMD and th...
State-dependent modulation of retinothalamic axonal boutons
Summary Perception does not depend on environment alone, but also on brain state. Work from our lab and others show that visual responses to certain features are selectively gated...
Evaluating the Role of Sleep in the Development of Intensive Care Unit Delirium
PROJECT SUMMARY More than one third of patients in the intensive care unit (ICU) develop ICU delirium, an acute, fluctuating form of cognitive dysfunction that is associated with i...