Results for Environment
40,772 grants found
Showing 36,121 – 36,140 of 40,772 grants for "Environment"
CAREER: SHF: Chiplet-Package Co-Optimizations for 2.5D Heterogeneous SoCs with Low-Overhead IOs
Design of 2.5D chiplets is becoming increasingly popular as a flexible and scalable More-than-Moore solution to push computational performance of integrated circuit chips. With het...
RESEARCH-PGR: Developing novel strategies to enhance the tolerance of crops to a combination of drought and heat stress.
Heat waves occurring during periods of drought stress have a devastating impact on agricultural production and yield. A combination of drought and heat stress occurring during the...
Acyl-CoA synthetase-mediated regulation of lipid homeostasis
PROJECT SUMMARY / ABSTRACT Systemic lipid homeostasis is controlled by the liver via complex but precisely regulated biochemical, signaling, and cellular pathways.In obesity, hepat...
State-dependent modulation of retinothalamic axonal boutons
Summary Perception does not depend on environment alone, but also on brain state.Work from our lab and others show that visual responses to certain features are selectively gated d...
Engineering a Vascularized Brain-Chip for Probing and Evaluating Mechanisms of Alzheimer’s Disease
An estimated 1 in 10 Americans age 65 and older are currently living with Alzheimer?s Disease (AD), yet there is still no pharmacologic treatment available that can slow or stop th...
The Health Sciences & Technology Academy – Alabama (HSTA-AL)
Project Summary/Abstract This innovative project will replicate the successful Health Sciences & Technology Academy from West Virginia, with important adaptations for our purpo...
Role of astrocyte-based cholinergic neuromodulation in cognition and in the treatment of cognitive disorders
ABSTRACT Neurons are viewed as the cellular correlate of cognition and only target of clinical therapeutics, in part because manipulating neurons rapidly and directly alters behavi...
Determining how the epigenome serves as the interface between exercise and facilitated memory formation in the adult and aging female and male brain
Project Summary/Abstract Normal aging is accompanied by a decline in the capability to learn, form new memories and to retrieve previously established ones.Given a steady increase...
Development of Faux-Biotics to combat the spread of hospital-acquired antibiotic-resistant infections
Project Summary The CDC considers the escalation of antibiotic resistance to be one of the biggest public health concerns of our time.Antibiotic resistance is a major issue both hu...
Link between early gut dysfunction and amyloid beta aggregation in Alzheimer's Disease related dementia
PROJECT SUMMARY In recent years, it has become apparent that a “gut-brain” axis exists where communication occurs between the gut, its microbiota, the immune system and the brain....
Evaluating the Role of Sleep in the Development of Intensive Care Unit Delirium
PROJECT SUMMARY More than one third of patients in the intensive care unit (ICU) develop ICU delirium, an acute, fluctuating form of cognitive dysfunction that is associated with i...
Collaborative Research: Moving Beyond the Margins: Modeling Water Availability and Habitable Terrestrial Ecosystems in the Polar Desert of the McMurdo Dry Valleys
Part I: Non-technical description:Water is life and nowhere is it more notable than in deserts. Within the drylands on Earth, the Antarctic deserts, represented in this study by th...
Collaborative Research: Moving Beyond the Margins: Modeling Water Availability and Habitable Terrestrial Ecosystems in the Polar Desert of the McMurdo Dry Valleys
Part I: Non-technical description:Water is life and nowhere is it more notable than in deserts. Within the drylands on Earth, the Antarctic deserts, represented in this study by th...
Collaborative Research: Moving Beyond the Margins: Modeling Water Availability and Habitable Terrestrial Ecosystems in the Polar Desert of the McMurdo Dry Valleys
Part I: Non-technical description:Water is life and nowhere is it more notable than in deserts. Within the drylands on Earth, the Antarctic deserts, represented in this study by th...
Collaborative Research: Moving Beyond the Margins: Modeling Water Availability and Habitable Terrestrial Ecosystems in the Polar Desert of the McMurdo Dry Valleys
Part I: Non-technical description:Water is life and nowhere is it more notable than in deserts. Within the drylands on Earth, the Antarctic deserts, represented in this study by th...
CAREER: Virtual Reality Simulations of Moral Decision Making for Autonomous Vehicles
Accidents with Autonomous Vehicles (AVs) attest to the need to consider the ethical issues inherent in AVs use, and the ethical goal functions they will be programmed to follow. Wo...
New Applicant Grant: Exploring the connection between solar flare energetic electrons observed at the Sun and in the heliosphere
The Solar Physics Group at Northumbria University has a long-term research programme to understand the physics of our closest star, the Sun, and other solar-like stars. The Sun dis...
Reading Solar System Science 2020
In Reading Solar System Science, we propose five independent projects to gain further insight and understanding in solar and heliospheric physics, magnetospheric plasma processes a...
Global Gene Expression Responses of Francisella tularensis to intracellular Infection of Human Alveolar Macrophages
Francisella tularensis, the cause of tularemia, is a highly virulent intracellular pathogen and a Tier 1 select agent with the potential to cause severe disease as an airborne biow...
Global Gene Expression Responses of Francisella tularensis to intracellular Infection of Human Alveolar Macrophages
Francisella tularensis, the cause of tularemia, is a highly virulent intracellular pathogen and a Tier 1 select agent with the potential to cause severe disease as an airborne biow...