Results for Environment
40,772 grants found
Showing 36,041 – 36,060 of 40,772 grants for "Environment"
Natural History and Mechanisms of Exocrine Pancreatic Dysfunction in Pre-Type 1 Diabetes
PROJECT SUMMARY. Type 1 diabetes (T1D) is historically described as an endocrine (β-cell) specific autoimmune disease. However, reduced pancreatic size and subclinical exocrine ins...
Utilizing Causal X-Linked Intellectual Disability Variants to Gain Insight into the O-GlcNAc Transferase Enzyme
Summary: Approximately 1 in 500 males in the United States are affected by X-Linked Intellectual Disability (XLID). Our laboratory has previously characterized several mutations in...
Natural History and Mechanisms of Exocrine Pancreatic Dysfunction in Pre-Type 1 Diabetes
PROJECT SUMMARY. Type 1 diabetes (T1D) is historically described as an endocrine (β-cell) specific autoimmune disease. However, reduced pancreatic size and subclinical exocrine ins...
NSF-DFG Confine: Plasma-Catalysis in Confined Spaces for Cold Start NOx Abatement in Automotive Exhaust
This project seeks to transform traditional chemical processing to ensure a sustainable future. Catalysis, which facilitates desired chemical reactions, has played a key role in de...
PIRE: Climate risk, pollution, and childhood inequalities in low- and middle-income countries
Concern is rapidly increasing about accelerating climate changes and their implications for the health and welfare of children. In a recent press release, the United Nations Childr...
Probing the rules of molecular recognition through the de novo design of proteins that bind small-molecule drugs.
Project Summary/Abstract: Designing ligand-binding proteins from scratch is the ultimate test of the principles of molecular recognition by proteins. Emerging technologies recently...
Sialic acid mediated interbacterial adhesion among oral bacteria
PROJECT SUMMARY/ABSTRACT Glycan-mediated interbacterial coadhesion is a critical part of multispecies biofilm formation in the human mouth. Certain strains of oral streptococci exp...
2023 Glial Biology: Functional Interactions Among Glia and Neurons Gordon Research Conference and Gordon Research Seminar
ABSTRACT The Gordon Research Conference on Glial Biology entitled Glial networking: Cell biology, physiology and plasticity will host its 10th meeting in 2023 in Ventura, Californi...
Binaural processing and hearing in children with cochlear implants
Abstract There is strong clinical impetus to provide bilateral hearing early in life, not only for safety in navigating the environment, but also to maximize learning and socializi...
NSFGEO-NERC: Collaborative Research: Using Time-series Field Observations to Constrain an Ocean Iron Model
Iron is an essential nutrient for the growth of phytoplankton in the oceans. As such, iron plays key roles in regulating marine primary production and the cycling of carbon. It is...
Stereoscopic Insight into Dilute Superconductivity of Perovskite Semiconductors
Non-technical AbstractUnderstanding the physical mechanism that gives rise to the phenomenon of superconductivity in some materials remains challenging, even decades after the firs...
Binaural processing and hearing in children with cochlear implants
Abstract There is strong clinical impetus to provide bilateral hearing early in life, not only for safety in navigating the environment, but also to maximize learning and socializi...
Novel freely moving monkey framework for the study of naturalistic behaviors
PROJECT SUMMARY/ABSTRACT Animals live in dynamic, ever-changing environments. As such, survival requires them to explore their environment and process the barrage of sensory signal...
Applications of the long-term culture human primordial germ cell-like cells to toxicological assessments and mechanistic studies on chemically caused heritable human health threats
Because germ cells are exclusively capable of passing the genetic materials to the progeny, damages to their genome – either involving DNA mutations or only affecting epigenetic ma...
Volumetric analysis of epithelial morphogenesis with high spatiotemporal resolution
Project Summary How epithelial sheets remodel themselves to adopt new tissue conformations through changes in neighbor relationships and cell shape dynamics has been a key question...
Molecular Analysis of Airway Secretory Cells in Health and Disease
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the US and worldwide, and it remains disease incurable in part due to an incomplete understandin...
Neuron-astrocyte mechanisms of norepinephrine in goal-directed learning
Decision-making for goal-directed actions via reinforcement learning (RL) is a fundamental component of complex behaviors. Central to RL theory is the balance between exploration a...
CAREER: Multimodal Brain and Body Music Interfaces to Promote Entrainment, Connection, and Creative Science Education
This award is funded in part under the American Rescue Plan Act of 2021 (Public Law 117-2).Entrainment is a process in which people’s natural brain and body rhythms synchronize, th...
The Robert T. Malison Yale-Chulalongkorn Stress, Alcohol Use and Psychopathology Training Program
Abstract Psychiatric disorders are a set of chronic, non-communicable diseases (NCDs), a global public health problem of enormous economic, social, and medical cost to the internat...
Neuron-astrocyte mechanisms of norepinephrine in goal-directed learning
Decision-making for goal-directed actions via reinforcement learning (RL) is a fundamental component of complex behaviors. Central to RL theory is the balance between exploration a...