Results for Environment
40,772 grants found
Showing 35,701 – 35,720 of 40,772 grants for "Environment"
Anatomical and functional imaging of the conventional outflow pathway
Project Summary: Glaucoma is the leading cause of irreversible blindness worldwide. Currently, the only effective treatment for glaucoma is intraocular pressure (IOP) reduction. Ph...
INnovative data Science to Impact the TB Epidemic - INSITE
PROJECT SUMMARY There are limited opportunities in Africa to work with routine clinical and health data at scale, and to develop the expertise to process these data in an environme...
Nurse-Led Interventions in Pediatric Critical Care: Training in Pediatric Sleep Health, Delirium, and Multi-Site Research
PROJECT SUMMARY/ABSTRACT Delirium is a serious, potentially iatrogenic, complication of pediatric intensive care unit (PICU) care and is associated with poor clinical outcomes. Poo...
Investigating HDAC3 phosphorylation as an epigenetic regulator of memory formation in the adult and aging brain
Project Summary/Abstract Failure to form and store long-term memories is a feature of cognitive decline in aging and neurodegeneration. Experts predict that the prevalence of cogni...
BRAIN CONNECTS: The center for Large-scale Imaging of Neural Circuits (LINC)
Project summary: This project will develop and validate a comprehensive toolset of novel technologies for imaging axonal projections across scales, and will deploy this toolset to...
Turning on Persistence: Novel Molecular Determinants that Underpin P. gingivalis' Intracellular Survival In Epithelial Cells
SUMMARY of The PARENT AWARD A growing multidisciplinary evidence critically underpins that Porphyromonas gingivalis, a leading pathobiont of the oral cavity that successfully remod...
Function and Targeting of ETV6 in Ewing Sarcoma
PROJECT SUMMARY/ABSTRACT Ewing sarcoma is a highly aggressive bone and soft tissue tumor mainly affecting children and young adults, which still lacks effective therapy. Due to its...
Analgesic-Behavioral and Neurophysiological Correlates of Opioid-Sparing Spinal Anesthesia Compared to General Anesthesia in Human Infants
Each year, approximately 6 million children receive anesthesia in the United States alone. The ongoing opioid epidemic has forced the medical community to examine how it uses opioi...
Medical Scientist Training Program
Project summary The University of Pennsylvania MD/PhD and VMD/PhD programs were established in 1958 and 1969, and united as a single medical scientist training program in 1977. The...
Medical Scientist Training Program
PROJECT SUMMARY The mission of the Albert Einstein College of Medicine Medical Scientist Training Program (MSTP) is to train physician-scientists who will become leaders in biomedi...
Investigating the effects of olfactory critical period odorant exposure on the trace amine-associated receptor4 olfactory circuit
Project Summary Innate behavioral responses to emotionally salient cues in the environment are thought to be set in the brain through hardwired circuits. In mice, the olfactory det...
From Human-Powered to Automated Video Description for Blind and Low Vision Users
Project Summary Approximately 12 million people in the United States have been diagnosed with a visual impairment. These individuals face unique challenges in our modern environmen...
Risk factors for chronic obstructive pulmonary disease exacerbations, quality of care, and outcomes in people with HIV
PROJECT SUMMARY AND ABSTRACT Chronic obstructive pulmonary disease (COPD) is an important public health problem in people with HIV (PWH). PWH have 3-fold the odds of COPD as uninfe...
Identifying the core transcriptional regulatory network initiating a tooth program
PROJECT SUMMARY: Loss of teeth due to oral disease, trauma, aging or congenital defects is one of the most common organ failures. The first morphological sign of tooth development...
Contribution of the sacral neural crest to the peripheral nervous system of the post-umbilical gastrointestinal tract
The enteric nervous system (ENS), the largest portion of the peripheral nervous system, is derived fromneural crest populations referred to as “vagal” and “sacral”, arising from th...
The PILI 'Āina Project
SUMMARY Native Hawaiians have the highest prevalence of cardiometabolic diseases of any population in Hawai‘i. Diet is strongly implicated as a cause of these disparities. Native H...
Dynamic multimodal connectivity analysis of brain networks in focal epilepsy
PROJECT SUMMARY/ABSTRACT Epilepsy is a debilitating neurological disorder that affects 1% of the population worldwide and temporal lobe epilepsy (TLE) is the most common form. Seiz...
Training Program in Cellular and Molecular Biology and Genetics
PROJECT SUMMARY / ABSTRACT The CMBG program trains graduate students for the PhD degree in Cell & Molecular Biology and Genetics. The program includes 54 proposed faculty from...
Deciphering neural crest-specific TFAP2 pathways in midface development and dysplasia
PROJECT SUMMARY: Craniofacial anomalies are the 2nd leading structural malformation to appear at birth, with the most common forms occurring in the mid- and upper-face regions. How...
Function and Targeting of ETV6 in Ewing Sarcoma
PROJECT SUMMARY/ABSTRACT Ewing sarcoma is a highly aggressive bone and soft tissue tumor mainly affecting children and young adults, which still lacks effective therapy. Due to its...