Results for Environment
40,772 grants found
Showing 35,681 – 35,700 of 40,772 grants for "Environment"
Democratizing CAR T cell therapy by in situ programming of virus-specific T cells
Engineered T cells that express chimeric antigen receptors (CARs) have shown remarkable efficacy against hematological malignancies. However, broad implementation of CAR T cell the...
Skin microbiome regulation of the sebum-immune axis
Summary The skin forms a protective barrier against harmful substances and pathogens that we contact through our immediate environment. Specialized glands in the skin known as seba...
Democratizing CAR T cell therapy by in situ programming of virus-specific T cells
Engineered T cells that express chimeric antigen receptors (CARs) have shown remarkable efficacy against hematological malignancies. However, broad implementation of CAR T cell the...
An interactive, narrative intervention to address the mental health treatment gap among young people living with HIV in Nigeria
PROJECT SUMMARY Young people living with HIV (Y-PLWH) have poor adherence to antiretroviral therapy and engagement in HIV care, making HIV the leading cause of death for African ad...
Career Enhancement Core
PROJECT SUMMARY - CAREER ENHANCEMENT CORE The goal of the Career Enhancement Core (CEC) is to foster the development of researchers planning to engage in the field of tobacco regul...
Hawaii Minority Health and Cancer Disparities SPORE
Project Summary/Abstract At the root of health disparities is the diversity that exists in the biological, behavioral, sociocultural, and environmental characteristics of individua...
Poverty-Related Risk Factors for Auditory and Language Deficits in Children
Project Summary/Abstract Ever since Lyndon Johnson declared a War on Poverty in the 1960s, developmental scientists have been assessing the effects of poverty on child development,...
Dissecting the Mechanims of Platelet-Fibrin interaction
Project Summary/Abstract Platelets play a pivotal role in hemostasis and thrombosis as they are required for platelet aggregation which contributes to both the arrest of bleeding a...
Wearable Wireless Respiratory Monitoring System that Detects and Predicts Opioid Induced Respiratory Depression
PROJECT SUMMARY. Opioids are the most prescribed drug in US hospitals, and opioid induced respiratory depression (OIRD) is a widespread and life-threatening problem. Episodes of OI...
A Healthy Weight Intervention for Family Stress during the Early Phases of ALL Treatment: NOURISH-ALL
PROJECT SUMMARY/ABSTRACT Excessive weight gain leading to obesity is common during the early phases of pediatric acute lymphoblastic leukemia (ALL) treatment, and results in higher...
Non-invasive Condition Monitoring of Ventricular Assistive Devices Using Automated Advanced Acoustic Methods
PROJECT SUMMARY The primary objective of this research project is to create a new approach to identifying the state-of-health of implanted ventricular assist devices (VAD) using no...
MicroRNA 374 as an Epigenetic Regulator of Chronic Pain
Abstract Chronic primary pain conditions (CPPCs) such as fibromyalgia and temporomandibular disorder (TMD) constitute a significant healthcare problem that affects over 100 million...
2023 International TSC Research Conference
The goals of the 2023 International TSC Research Conference are to (1) inspire new research directions by exposing trainees and researchers from outside the field and belonging to...
CollaLink: Guided-regenerative Scaffold for Augmentation of Anterior Cruciate Ligament Repair
Summary Tears of the anterior cruciate ligament (ACL) lead to instability of the knee and reduce mobility. An estimated 225,000 ACL tears are reported annually in the US, equating...
The Gut-Liver Axis in HIV-Related Non-Alcoholic Fatty Liver Disease
Project Summary/Abstract Liver disease is a leading cause of mortality in persons with HIV (PWH), and PWH suffer a disproportionate burden of non-alcoholic fatty liver disease (NAF...
Segmentation and integration of experience in hippocampal neuronal representations
An episodic memory is a set of moments recalled together; these moments often share a unique combination of time, location, and content. Despite our experience with memories as fal...
Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg (Mass-ENVISION)
Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg (Mass-ENVISION) is a proposed new Alzheimer's-related Resource Centers for Minority Aging...
The Gut-Liver Axis in HIV-Related Non-Alcoholic Fatty Liver Disease
Project Summary/Abstract Liver disease is a leading cause of mortality in persons with HIV (PWH), and PWH suffer a disproportionate burden of non-alcoholic fatty liver disease (NAF...
Role of TRIM46 in neuronal polarity in vivo
PROJECT SUMMARY. From movement to memory, the complex and wide-ranging tasks performed by the nervous system depend on the polarization of billions of neurons into two functionally...
Exploiting Pf phage superinfection to lower Pseudomonas aeruginosa virulence via evolutionary tradeoffs
PROJECT SUMMARY Many clinically relevant pathogens have bacteriophage (phage) genomes integrated in their chromosome (prophages), which can have large effects on the bacteria’s phe...