Results for Environment
40,772 grants found
Showing 35,501 – 35,520 of 40,772 grants for "Environment"
Investigating Cellular Senescence at the Single Cell Level
Project Summary/Abstract Aging is a key risk factor for chronic disease development which can affect lifespan and quality of life. Cellular senescence has emerged as a potential ta...
Rethinking Legionella pneumophila type IV pili and their roles in intracellular infection
PROJECT SUMMARY / ABSTRACT Legionella pneumophila (Lp) is the agent of Legionnaires disease, an oft-fatal form of pneumonia that is increasing in incidence. In natural and man-made...
Advancing RAS pathway targeted therapy in NF1-MPNST: effects of SHP2 and CDK4/6 inhibitors on the tumor and the tumor immune microenvironment
PROJECT SUMMARY/ ABSTRACT There has been little advancement in overall survival for patients with malignant peripheral nerve sheath tumor (MPNST), despite decades of research and m...
Rethinking Legionella pneumophila type IV pili and their roles in intracellular infection
PROJECT SUMMARY / ABSTRACT Legionella pneumophila (Lp) is the agent of Legionnaires disease, an oft-fatal form of pneumonia that is increasing in incidence. In natural and man-made...
Harnessing neutrophils to improve the efficacy of immune checkpoint inhibitors in breast cancer
Project Summary Breast cancer has been the most prevalent cancer and the second leading cause of cancer-related death in American women for many years. Immune checkpoint inhibitors...
Harnessing neutrophils to improve the efficacy of immune checkpoint inhibitors in breast cancer
Project Summary Breast cancer has been the most prevalent cancer and the second leading cause of cancer-related death in American women for many years. Immune checkpoint inhibitors...
Impact of Structural Racism on Racial Disparities in Cognitive Impairment
It cognitive estimated is estimated that 65% of individuals experience some level of cognitive impairment by 70-years of age. Within impairment, Alzheimer's disease and relate...
The antigen specificity of tumor-targeting T cells in non-small cell lung cancer
PROJECT SUMMARY This proposal outlines a five-year training program for Dr. Mark Lee, M.D., Ph.D., with the goal of preparing him for an independent academic research career as a p...
Auditing Social Media Algorithmic Pathways to Measure Prevalence of Online Misinformation Related to Opioid Misuse
Abstract: Opioid misuse has become a public health epidemic in the United States with more than 70% of indi- viduals with an opioid use disorder (OUD) never receiving any sort of t...
Impact of Structural Racism on Racial Disparities in Cognitive Impairment
It cognitive estimated is estimated that 65% of individuals experience some level of cognitive impairment by 70-years of age. Within impairment, Alzheimer's disease and relate...
Auditing Social Media Algorithmic Pathways to Measure Prevalence of Online Misinformation Related to Opioid Misuse
Abstract: Opioid misuse has become a public health epidemic in the United States with more than 70% of indi- viduals with an opioid use disorder (OUD) never receiving any sort of t...
The antigen specificity of tumor-targeting T cells in non-small cell lung cancer
PROJECT SUMMARY This proposal outlines a five-year training program for Dr. Mark Lee, M.D., Ph.D., with the goal of preparing him for an independent academic research career as a p...
CAREER: Aquatic Therapy Assist-Tool Using a Real-Time Underwater Physiological and Musculokinetic Monitoring in Personalized Stroke Rehabilitation
Aquatic therapy is a type of physical therapy that takes place in water and is widely used to help stroke patients recover. Water has benefits that make it easier and less painful...
The Medical District UTSW-D FIRST Program
OVERALL: ABSTRACT This Dallas Medical District UTSW-D FIRST proposal is submitted jointly by the University of Texas Southwest- ern Medical Center (UTSW) and the University of Texa...
FuSe-TG: Heterogeneous module, array antenna, and IC co-design for energy-efficient D-band wireless communications and radar
Future wireless communication and radar technologies above 100 GHz will enable high-speed data transmission and high-resolution radar sensing, which will be the foundation to enabl...
A Healthy Weight Intervention for Family Stress during the Early Phases of ALL Treatment: NOURISH-ALL
PROJECT SUMMARY/ABSTRACT Excessive weight gain leading to obesity is common during the early phases of pediatric acute lymphoblastic leukemia (ALL) treatment, and results in higher...
Traumatic Events and Injury: Etiologic Mechanisms for Temporomandibular Disorders
Project Summary/Abstract Regional injury affecting the jaw, compared to other well-known risk determinants, is among the strongest risk determinants both for first life-time onset...
Sensory neuron-skin interaction in health and disease
PROJECT SUMMARY My career goal is to lead an independent research group to investigate the pathology and resolution of pain to solve neuropathic pain problems. To achieve this goal...
COVID-19 and the Health and Wellbeing of Vulnerable Service Sector Workers across the Life Course
ABSTRACT The COVID-19 pandemic precipitated intermingled health and economic shocks, which were felt deeply in the service-sector. The service-sector workforce is large, with nearl...
Bisphenol-Induced Blood-Brain Barrier Dysfunction in Alzheimer’s Disease
Identifying environmental risk factors for Alzheimer’s Disease (AD) is critical to mitigate cognitive decline in humans. We provide first evidence showing that endocrine disrupting...