Results for Environment
40,772 grants found
Showing 35,461 – 35,480 of 40,772 grants for "Environment"
Dose Flexible Combination 3D-Printed Delivery Systems for Antiviral Therapy in Children
ABSTRACT/SUMMARY An estimated 1.7 million children aged 0-14 were living with HIV, and at least 300,000 children were newly infected with HIV in 2020. Another 120,000 children died...
Regulation of seizure timing by circadian rhythms and sleep
PROJECT SUMMARY/ABSTRACT Candidate and Plan for Career Development: I am a clinical neurogeneticist with a background in molecular neuroscience interested in the interactions betwe...
The geometry of neural representations reflecting abstraction in humans
ABSTRACT The process of abstraction involves identifying the features shared across past experiences so as to represent a complex environment using only a small number of variables...
Comfort eating in the Eating in America Study: New insights to inform prevention and intervention efforts across the lifespan
About 35% of U.S. adults engage in comfort eating, defined as increasing one’s food intake or eating high- calorie/fat/sugar foods in response to stress or other negative emotions....
Regulation of seizure timing by circadian rhythms and sleep
PROJECT SUMMARY/ABSTRACT Candidate and Plan for Career Development: I am a clinical neurogeneticist with a background in molecular neuroscience interested in the interactions betwe...
REU Site: Soft Materials for Applications in Sustainability and Healthcare Engineering
This new three year REU Site entitled "Soft Materials for Applications in Sustainability and Healthcare Engineering" hosted by the University of Notre Dame offers ten stu...
Neurovascular circadian oscillation in health and Alzheimer's disease
ABSTRACT Alzheimer’s disease is a devastating chronic neurodegenerative disease and the leading cause of dementia in older adults. One of the hallmark pathologies of Alzheimer’s di...
Heme-, Redox-, and CO-dependent Regulation of Heme Homeostasis
Heme oxygenases (HO2 and HO2) and Rev-Erbβ play critical roles in cytoprotection and in heme-dependent CO metabolism and signaling. HO2 and Rev-Erbβ exhibit similarities in their m...
Imaging epigenetic dysregulation in the Lewy body dementias with [11C]Martinostat
Accumulating evidence suggests that epigenetic changes - functional modifications to the genome that do not change the DNA sequence and that provide a powerful mechanism by which e...
Preliminary Implementation of an Informational Nudge to Improve Heart Failure Prescribing
Background: VA has experience with strategies to promote guideline-concordant heart failure (HF) care but there is a need for greater innovation. Nudge theory is a field within beh...
StuDy AimED at Increasing AlCohol AbsTinEnce (DEDICATE)
PROJECT SUMMARY/ABSTRACT The long-term objective of this award is to support Dr. Hagar Hallihan, an African American woman, in advanced training in clinical research and neuroscien...
Advancing RAS pathway targeted therapy in NF1-MPNST: effects of SHP2 and CDK4/6 inhibitors on the tumor and the tumor immune microenvironment
PROJECT SUMMARY/ ABSTRACT There has been little advancement in overall survival for patients with malignant peripheral nerve sheath tumor (MPNST), despite decades of research and m...
Emergent Technology for Studying the Structure/Function Relationship of Enzymes Using Electron Paramagnetic Resonance
PROJECT SUMMARY/ABSTRACT: Electron paramagnetic resonance (EPR) is a spectroscopic technique that measures the absorption of energy by unpaired electrons and is used to monitor int...
Emergent Technology for Studying the Structure/Function Relationship of Enzymes Using Electron Paramagnetic Resonance
PROJECT SUMMARY/ABSTRACT: Electron paramagnetic resonance (EPR) is a spectroscopic technique that measures the absorption of energy by unpaired electrons and is used to monitor int...
BRIDGING - Breakthrough interview extended reality training towards reducing the autism employment gap
Background Meaningful work enables people to lead independent and rewarding lives. Whilst over 50% of autistic people are believed to be able to undertake paid work, data shows tha...
Social Vulnerability, Sleep, and Early Hypertension Risk in Younger Adults
PROJECT SUMMARY/ABSTRACT This K23 Career Development Award will support Dr. Allison Gaffey’s development into an independent patient-oriented investigator with a focus on women’s r...
Quantitative Electrophysiology to Link Neuroplasticity, Brain State, and Behavioral Change in Human Visual Cortex
PROJECT SUMMARY / ABSTRACT Rehabilitation of central visual disorders like amblyopia and cortical visual impairment depends on synaptic plasticity, the changes in synaptic connecti...
Adaptations to the COVID-19 Pandemic: Pre-Pandemic Continuity and Changes in Emotional Well-Being
ABSTRACT COVID-19 pandemic-related stressors have altered Americans’ daily lives, but variation in the effects on emotional well-being cannot be determined from existing studies be...
mGlide-Care: A mHealth Partnership with Care Givers to Improve HTN Management in Patients with Cognitive Impairment
Project Summary The principal investigator Dr. Lakshmi’s goal is to develop evidence-based technology interventions that support chronic disease care in older persons including tho...
Mentoring Multidisciplinary Patient-Oriented Research in TB, HIV, and Global Health
Dr. Shah is a physician-scientist with 15-years of experience leading patient-oriented research (POR) on diagnosis, treatment, and prevention of tuberculosis (TB) globally, includi...