Results for Environment
40,772 grants found
Showing 35,401 – 35,420 of 40,772 grants for "Environment"
The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve Health
ABTRACT The Ohio State University (OSU) Center for Clinical and Translational Science (CCTS) was formed in 2007, with the vision to advance today’s discoveries to improve health fo...
Investigating the mechanism of self-organized cortical patterning in an artificial cortex
The cell cortex underlies essential cellular functions, including cell shape changes that facilitate cell division.Comprised of a meshwork of filamentous actin (F-actin) and the pl...
Mast Cell Activation as a Common Mechanism of Pulmonary Toxicity by Chemical Threat Agents
Project Abstract The Department of Homeland Security considers numerous chemical threat agents a concern for human health, specifically those that are acute pulmonary toxicants. In...
Food-Body-Mind Intervention: Promote whole child health
ABSTRACT Mental, emotional, and behavioral (MEB) disorders begin in early childhood, with one in six US preschoolers aged 3-5-years diagnosed with a MEB disorder. Children from low...
Collaborative Research: RI: Medium: Bridging the Semantic-Metric Gap via Multinocular Image Integration
Humans and other animals can effortlessly and subconsciously reconstruct the 3D world around them from the video imagery streaming to their eyes, and successfully use it for naviga...
Food-Body-Mind Intervention: Promote whole child health
ABSTRACT Mental, emotional, and behavioral (MEB) disorders begin in early childhood, with one in six US preschoolers aged 3-5-years diagnosed with a MEB disorder. Children from low...
The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve Health
ABTRACT The Ohio State University (OSU) Center for Clinical and Translational Science (CCTS) was formed in 2007, with the vision to advance today’s discoveries to improve health fo...
Investigating how xenobiotics interact with phages to shift energy balance
Project Summary Obesity is a major public health concern associated with several co-morbidities, such as metabolic syndrome, type 2 diabetes, and cardiovascular disease. Many presc...
Multimodal omics approach to identify health to cardiometabolic disease transitions
Abstract: The global obesity epidemic drives the high prevalence of cardiometabolic disorders (CMDs), including type 2 diabetes (T2D), and non-alcoholic fatty liver disease (NAFLD)...
Mechanisms of Open and Hidden Placebo in Stroke Recovery
ABSTRACT We propose investigating the neural mechanisms of placebo (open and hidden) in stroke subjects. This proposal is built on our recently completed clinical trial NIH R21 (R2...
Mechanisms of Open and Hidden Placebo in Stroke Recovery
ABSTRACT We propose investigating the neural mechanisms of placebo (open and hidden) in stroke subjects. This proposal is built on our recently completed clinical trial NIH R21 (R2...
Fast-kinetics approaches to define direct gene-regulatory functions of MYB in leukemia
Project Summary/Abstract Acute myeloid leukemia (AML) remains a therapeutic challenge and a significant public health burden, necessitating development of novel therapies. The tran...
Assessment of a Radiomics-Based Computer-Aided Diagnosis Tool for Cancer Risk Stratification of Pulmonary Nodules
PROJECT SUMMARY/ABSTRACT This proposal describes a comprehensive 5-year mentored career development plan with the goal of training the candidate to become a leading independent phy...
Role of type 1 IFN in eye infection
ABSTRACT HSV-1 infection is a leading cause of eye disease and genital herpes but no HSV-1 vaccines have shown efficacy in humans. It elicits only a partially protective immune res...
A systems biology approach to elucidate the biology of immune-associated outcomes in breast cancer
PROJECT SUMMARY This K01 application seeks protected time for mentored research and career development training for Dr. Rosalyn Sayaman, PhD to successfully transition to tenure-tr...
Nuclear receptor regulation of epigenetic mechanisms regulating HIV CNS latency
Background. This proposal entitled “"Nuclear receptor regulation of epigenetic mechanisms regulating HIV CNS latency" is submitted in response to RFA-MH-22-280: Epigeneti...
Intersectional Stigma Reduction for Tajik Migrants Who Inject Drugs
Project Summary Labor migration is a major contributor to fueling the global AIDS epidemic and also the movement of HIV across country borders and populations. Migrants who inject...
Intersectional Stigma Reduction for Tajik Migrants Who Inject Drugs
Project Summary Labor migration is a major contributor to fueling the global AIDS epidemic and also the movement of HIV across country borders and populations. Migrants who inject...
A systems biology approach to elucidate the biology of immune-associated outcomes in breast cancer
PROJECT SUMMARY This K01 application seeks protected time for mentored research and career development training for Dr. Rosalyn Sayaman, PhD to successfully transition to tenure-tr...
Bridging the gap: joint modeling of single-cell 1D and 3D genomics
PROJECT SUMMARY/ABSTRACT Advances in single-cell technologies have enabled three-dimensional (3D) genome structure profiling and simultaneous capture of the transcriptome and epige...