Results for Environment
40,772 grants found
Showing 35,321 – 35,340 of 40,772 grants for "Environment"
The role of remission in the intergenerational transmission of alcohol use disorder: Course, context, and offspring outcomes
Project Summary Abstract The economic, physical and emotional harms borne by AUD-affected families are great. 7.5 million U.S. children live with an AUD-affected parent and have in...
Identification and characterization of molecular subtypes of Alzheimer's disease associated with cognitive function through cross-omics data integration
Project Summary/Abstract The goal of this mentored career development award is to provide a robust course of training in the biology of neurodegeneration and aging for Dr. Eteleeb,...
An automated machine learning approach to language changes in Alzheimer’s disease and frontotemporal dementia across Latino and English-speaking populations
PROJECT SUMMARY Alzheimer's disease (AD) and frontotemporal dementia (FTD) are highly prevalent in Latinos, the largest and fastest-growing minority in the United States (US)....
Enabling Older Adults to 'LiveWell' with Advanced Heart Failure: Development of a Palliative Rehabilitation Model
PROJECT SUMMARY/ABSTRACT Americans aged 65-years and older account for 70% of heart failure (HF)-related hospitalizations each year, and many in this population are burdened by mul...
Biomarkers for Brain Resetting as an Assistive Tool in the Treatment of Status Epilepticus
The proposed phase-I STTR research is an interdisciplinary effort to develop more effective clinical management of Status Epilepticus (SE) in collaboration with one of the leading...
Determination of structure-function relationships and role in virulence of a MerR-type regulator that mediates zinc tolerance in Streptococcus mutans
Abstract Dental caries is the most prevalent chronic infectious disease, with an estimated treatment cost of ~$70 billion/year. While a multifactorial disease, Streptococcus mutans...
The role of remission in the intergenerational transmission of alcohol use disorder: Course, context, and offspring outcomes
Project Summary Abstract The economic, physical and emotional harms borne by AUD-affected families are great. 7.5 million U.S. children live with an AUD-affected parent and have in...
Determination of structure-function relationships and role in virulence of a MerR-type regulator that mediates zinc tolerance in Streptococcus mutans
Abstract Dental caries is the most prevalent chronic infectious disease, with an estimated treatment cost of ~$70 billion/year. While a multifactorial disease, Streptococcus mutans...
Impact of Biomass Burning Aerosol and Humic-like Substances on Iron Homeostasis and Atherosclerosis
PROJECT SUMMARY/ABSTRACT Wildfire smoke exposure is thought to be responsible for increased morbidity and 339,000 annual deaths, but little is known about cardiovascular (CV) effec...
Impact of Biomass Burning Aerosol and Humic-like Substances on Iron Homeostasis and Atherosclerosis
PROJECT SUMMARY/ABSTRACT Wildfire smoke exposure is thought to be responsible for increased morbidity and 339,000 annual deaths, but little is known about cardiovascular (CV) effec...
The Contribution of Repetitive Head Impacts and Social Determinants of Health to Alzheimer's Disease and Related Dementia in Older Adult Black Men
ABSTRACT. Black Americans face nearly double the risk of Alzheimer’s disease (AD) and related compared to Whites. Black American men may be at increased risk for late-life neurolog...
An automated machine learning approach to language changes in Alzheimer’s disease and frontotemporal dementia across Latino and English-speaking populations
PROJECT SUMMARY Alzheimer's disease (AD) and frontotemporal dementia (FTD) are highly prevalent in Latinos, the largest and fastest-growing minority in the United States (US)....
Workshop Proposal: Enabling interdisciplinary and collaborative science through integration of biological and environmental data
During the last two decades, a wealth of data on biodiversity and associated environments have been mobilized in digital form. Collectively, these data provide a powerful resource...
Longitudinal changes in vascular and autonomic function in premenopausal women with PTSD
Project Summary The ultimate objective of this R03 proposal is to enable Dr. Ida Fonkoue to launch her independent research career by 1) expanding her current K01 research objectiv...
SAI: Community-Centered Sociotechnical Innovation to Tackle Urban Polycrises
Strengthening American Infrastructure (SAI) is an NSF Program seeking to stimulate human-centered fundamental and potentially transformative research that strengthens America’s inf...
Mineralocorticoid signaling in frog metamorphosis
This project focusses on how the hormone aldosterone functions to facilitate aquatic to terrestrial transitions in vertebrate animals. The processes of birth in humans, hatching in...
Project 1: Role of emergency myelopoiesis as a driver of clonal evolution in AML
PROJECT DESCRIPTION Our overall goals are to establish (i) whether the hijacking of emergency myelopoiesis (EM) pathways represents a shared mechanism of leukemogenesis in the cont...
Neuron vasculature interactions in pain
Neuropathic spontaneous pain, a main symptom of neuropathic pain, is often a particularly intractable clinical problem. While much has been done to understand the sensory sensitiza...
Memantine and Exercise for Chemotherapy-Related Cognitive Decline in Patients with Breast Cancer
PROJECT SUMMARY/ABSTRACT Chemotherapy-related cognitive decline (CRCD) is common and consequential to quality of life and function, but there is no standard of care to prevent or t...
UB Microbiome Center Gnotobiotic Animal Research Facility
PROJECT SUMMARY/ABSTRACT The University at Buffalo (UB) requests funds for critical research renovations and infrastructure upgrades in the Biomedical Education Building for the co...