Results for Environment
40,772 grants found
Showing 35,161 – 35,180 of 40,772 grants for "Environment"
Minimizing Hypoglycemia in Adults with Type 1 Diabetes through an Integrated Mobile Health and Continuous Glucose Monitoring System
Project Summary / Abstract Level 2 hypoglycemia (blood glucose
Genetic Contributors to White Matter Microstructure in Aging and Alzheimers Disease
PROJECT SUMMARY While reductions in medial temporal lobe (MTL) white matter tract microstructure have been suggested to have a central role in longitudinal cognitive decline in agi...
Midlife Obesity, Neurovascular Senescence and Cognitive Decline
Stefano Tarantini, PhD, is a junior aging researcher whose overarching goal is to develop an independent research program to understand and apply nutritional lifestyle intervention...
Integrating Health Records, Genomic, and Social Data to Stratify Adolescent Depression Risk
PROJECT ABSTRACT One in five adolescents in the United States will experience a depressive episode before age 18.Early prevention could offset a lifetime of morbidity including wor...
Investigation of Sirt1 activation to target IDH mutant glioma
Project Summary IDH mutant gliomas are incurable, primary brain tumors that affect young to middle-aged adults and are defined by a mutation in a key metabolic gene.Despite treatme...
The role of novel oncogenic histone H3 lysine variants in defining a therapeutically actionable epigenetic signature
PROJECT SUMMARY/ABSTRACT Over 1.7 million individuals will be diagnosed with cancer and 600,000 cancer-associated deaths will occur in the US in 2020.Devoting resources to develop...
Opioid Prescribing and Chronic Pain in the Primary Care Setting
Project Summary/Abstract Amidst high levels of chronic pain, the United States (U.S.) has seen a concurrent opioid overdose epidemic that has led to the deaths of an estimated 702,...
Resolving the Hierarchy and Regulation of Sebaceous Gland Stem Cells
PROJECT SUMMARY Sebaceous glands (SGs) are appendages of mammalian skin that produce and secrete a mixture of lipids, known as sebum.Sebum production is crucial for skin maintenanc...
CT Characteristics of Emphysema for Evaluation of Pulmonary Nodules
PROJECT SUMMARY/ABSTRACT The original description of the K23 project will not change ? as re-iterated below: Research: The National Lung Screening Trial (NLST) demonstrated a 20% r...
Charting the role of variability in learning across development
Project Summary/Abstract The way individuals learn from their environment reliably changes with age and experience.A common pattern observed across a wide range of cognitive tasks...
The role of novel oncogenic histone H3 lysine variants in defining a therapeutically actionable epigenetic signature
PROJECT SUMMARY/ABSTRACT Over 1.7 million individuals will be diagnosed with cancer and 600,000 cancer-associated deaths will occur in the US in 2020. Devoting resources to develop...
Opioid Prescribing and Chronic Pain in the Primary Care Setting
Project Summary/Abstract Amidst high levels of chronic pain, the United States (U.S.) has seen a concurrent opioid overdose epidemic that has led to the deaths of an estimated 702,...
Investigation of Sirt1 activation to target IDH mutant glioma
Project Summary IDH mutant gliomas are incurable, primary brain tumors that affect young to middle-aged adults and are defined by a mutation in a key metabolic gene. Despite treatm...
Cell-cell communication mediated by fluid flows
Project Summary Cells can detect external fluid flows across their surface. Such flows, and the flow signaling events they induce, are critical for organ development, homeostasis,...
MISC-IPV: A Community Based Intervention for Children Traumatized By Intimate Partner Violence
ABSTRACT One in four children (26%) in the U.S. are exposed to intimate partner violence (IPV), with higher rates among children of African American women. IPV exposure constitutes...
MISC-IPV: A Community Based Intervention for Children Traumatized By Intimate Partner Violence
ABSTRACT One in four children (26%) in the U.S. are exposed to intimate partner violence (IPV), with higher rates among children of African American women. IPV exposure constitutes...
Evidence-based sexual and reproductive health intervention using a multiphase optimization strategy
ABSTRACT Latina adolescents in the U.S. are disproportionately affected by HIV/AIDS/sexually-transmitted infections (STIs) and other adverse consequences of risky sexual behavior.T...
Using Zebrafish to Model Developmental and Multigenerational Volatile Organic Compound Toxicity
Project Summary: Trichloroethylene (TCE) and tetrachloroethylene (perchloroethylene; PERC) are two volatile organic compounds (VOCs) that significantly contaminate the environment...
Evidence-based sexual and reproductive health intervention using a multiphase optimization strategy
ABSTRACT Latina adolescents in the U.S. are disproportionately affected by HIV/AIDS/sexually-transmitted infections (STIs) and other adverse consequences of risky sexual behavior....
Evidence-based sexual and reproductive health intervention using a multiphase optimization strategy
ABSTRACT Latina adolescents in the U.S. are disproportionately affected by HIV/AIDS/sexually-transmitted infections (STIs) and other adverse consequences of risky sexual behavior....