Results for Environment
40,772 grants found
Showing 35,081 – 35,100 of 40,772 grants for "Environment"
Synergy of lipolysis and lipophagy in alcoholic liver disease
Project Summary/Abstract My long-term objective is to discover new cellular mechanisms that contribute to alcoholic liver disease (ALD), a progressive disease leading to non-revers...
Synergy of lipolysis and lipophagy in alcoholic liver disease
Project Summary/Abstract My long-term objective is to discover new cellular mechanisms that contribute to alcoholic liver disease (ALD), a progressive disease leading to non-revers...
Public Understanding of Big data in Genomics Medicine in Africa (PUBGEM-Africa)
Project Summary With rapid advanced in genomics, computational sciences, and health informatics, the next decade will likely experience a rapid interest in big data use to inform g...
Using technology-assisted stepped-care interventions to improve adherence in adolescents with asthma
PROJECT SUMMARY/ABSTRACT Candidate: I am a practicing pediatric psychologist whose overarching career goal is to improve health outcomes for adolescents with asthma by targeting ad...
HEALS™: An Active Hydrogen Sulfide Delivery Technique for Accelerated, Effective Wound Healing
Project Summary/Abstract The proposed effort addresses the need for novel therapeutic tools that improve chronic wound healing outcome. Recentstudies show that patients with diabet...
HEALS™: An Active Hydrogen Sulfide Delivery Technique for Accelerated, Effective Wound Healing
Project Summary/Abstract The proposed effort addresses the need for novel therapeutic tools that improve chronic wound healing outcome. Recentstudies show that patients with diabet...
Networking Core
PROJECT SUMMARY: NETWORK CORE Professional advancement of graduate students and postdoctoral fellows is critical to assure a sustained research workforce and to inspire a new gener...
Impact of sex differences on the trajectory of interactome dysfunctions across the AD spectrum
ABSTRACT The impact of sex differences in Alzheimer's disease (AD) remains poorly understood, especially in the context of protein-protein interactions within vulnerable regio...
Public Understanding of Big data in Genomics Medicine in Africa (PUBGEM-Africa)
Project Summary With rapid advanced in genomics, computational sciences, and health informatics, the next decade will likely experience a rapid interest in big data use to inform g...
Linking genomic, physiological, and behavioral responses using a Drosophila model of heavy metal stress
Contact PD/PI: Everman, Elizabeth PROJECT SUMMARY Heavy metal pollution has pervasive environmental, health, and evolutionary impacts. In humans, health risks of heavy metals rangi...
Modulation of ribosome velocity as a means to rescue refractory CF-causing variants
PROJECT SUMMARY (ABSTRACT) Cystic fibrosis (CF) is a lethal autosomal recessive disorder caused by mutation of the CF transmembrane conductance regulator (CFTR). The majority of CF...
Developing improved guidelines for nursing home-associated viral respiratory infections: Learning from the COVID-19 experience
PROJECT SUMMARY/ABSTRACT The COVID-19 pandemic highlighted the vulnerability of the nearly 1.4 million nursing home (NH) residents to respiratory healthcare associated infections (...
Intraflagellar transport process in primary cilium maintenance
PROJECT SUMMARY Primary cilia are non-motile antenna-like sensors that protrude into extracellular space for detecting a wide range of signals, including signals for cell prolifera...
The Impact of Donor Hematopoietic DNMT3A Mutations in Stem Cell Transplant Recipients
PROJECT SUMMARY/ABSTRACT Hematopoietic cell transplant (HCT) is an important treatment modality for patients with hematologic malignancy (HM). Its success depends on the ability of...
Enteroendocrine Regulation of Intestinal Metabolism
PROJECT SUMMARY Dr. Heather McCauley is mentored by Dr. James Wells at Cincinnati Children’s Hospital Medical Center (CCHMC), the largest pediatric research institution in the nati...
Ataxia Telangiectasia Mutated (ATM)-mediated hepatic DNA damage in pediatric nonalcoholic fatty liver disease
Pediatric nonalcoholic fatty liver disease (PNAFLD) is the leading cause of chronic liver disease in childhood. Progression from fatty liver (FL) to steatohepatitis (NASH) signific...
Driving Pressure as a Target for Lung-Protective Ventilation
PROJECT SUMMARY/ABSTRACT Sarina Sahetya, MD MHS is a pulmonary and critical care physician-scientist at Johns Hopkins University, with a Master’s degree in Clinical Investigation....
Human and Translational Immunology Training Program
Project Summary Progress in translational immunology has created a new demand for training scientists with expertise in human immunology and with the skills to bring discoveries in...
Function and regulation of constitutive protein translation in platelets
Project Summary The goals of this proposal are: 1) to elucidate the molecular signaling of protein translation initiation in circulating human platelets and characterize the plasma...
Decoding temporal epithelial signaling programs to restore homeostasis in acute lung injury
Abstract Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a common pulmonary syndrome with high mortality. ALI/ARDS stems from a communication breakdown between...