Results for Environment
40,772 grants found
Showing 34,881 – 34,900 of 40,772 grants for "Environment"
Antibiotic disruption of the gut microbiome and immune response in neonatal late-onset sepsis
PROJECT SUMMARY/ABSTRACT The goal of this proposal is to describe a five-year training and mentorship plan to prepare Drew Schwartz, MD, PhD to become an independent physician-scie...
Role of Legionella pneumophila Lvh TIVSS in virulence
Abstract.The Legionella genus has more than 60 species from which 20 are associated with Legionnaires? disease, a form of atypical pneumonia. More than 90% of Legionnaires? disease...
Role of Legionella pneumophila Lvh TIVSS in virulence
Abstract. The Legionella genus has more than 60 species from which 20 are associated with Legionnaires’ disease, a form of atypical pneumonia. More than 90% of Legionnaires’ diseas...
Predictive Modeling of the Functional and Phenotypic Impacts of Genetic Variants
PROJECT SUMMARY Genome-wide association studies (GWAS) have associated tens of thousands of common variants with human diseases and traits. The rapid expansion of Whole-Genome Sequ...
Predictive Modeling of the Functional and Phenotypic Impacts of Genetic Variants
PROJECT SUMMARY Genome-wide association studies (GWAS) have associated tens of thousands of common variants with human diseases and traits.The rapid expansion of Whole-Genome Seque...
Role of Legionella pneumophila Lvh TIVSS in virulence
Abstract. The Legionella genus has more than 60 species from which 20 are associated with Legionnaires’ disease, a form of atypical pneumonia. More than 90% of Legionnaires’ diseas...
Predictive Modeling of the Functional and Phenotypic Impacts of Genetic Variants
PROJECT SUMMARY Genome-wide association studies (GWAS) have associated tens of thousands of common variants with human diseases and traits. The rapid expansion of Whole-Genome Sequ...
Predictive Modeling of the Functional and Phenotypic Impacts of Genetic Variants
PROJECT SUMMARY Genome-wide association studies (GWAS) have associated tens of thousands of common variants with human diseases and traits. The rapid expansion of Whole-Genome Sequ...
Role of Legionella pneumophila Lvh TIVSS in virulence
Abstract. The Legionella genus has more than 60 species from which 20 are associated with Legionnaires’ disease, a form of atypical pneumonia. More than 90% of Legionnaires’ diseas...
Methylome-wide association study of socioeconomic status, incident type 2 diabetes, and cardiovascular disease events among African Americans
Project Abstract This NIH Ruth L.Kirschstein NRSA Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (F31) application is designed to enhance the tra...
Stakeholder Guidance to Anticipate and Address Ethical Challenges in Applications of Machine Learning and Artificial Intelligence in Algorithmic Medicine: a Novel Empirical Approach
PROJECT ABSTRACT The potential for artificial intelligence applications to enable more granular and pervasive measurement, prediction, and provide behavioral interventions offers i...
A pan-cancer atlas of driver mutations in >100,000 patients based on a hypothesis-driven combined computational and experimental approach
PROJECT SUMMARY Most mutations in cancer genomes are random passengers that do not contribute to oncogenesis, whereas only a few are drivers critical for tumor development.Existing...
Intraflagellar transport process in primary cilium maintenance
PROJECT SUMMARY Primary cilia are non-motile antenna-like sensors that protrude into extracellular space for detecting a wide range of signals, including signals for cell prolifera...
South Texas Alzheimer's Disease Center Administrative Core
PROJECT SUMMARY/ABSTRACT – Administrative Core The South Texas Alzheimer’s Disease Center (STAC) Administrative Core (AC), part of the collaborative effort of University of Texas H...
South Texas Alzheimer's Disease Center Research and Education Core
The cost of dementia care in the US will be $1 Trillion by 2050. Moreover, this burden will be highest among minorities, a group that is itself diverse. The Hispanic/Latino populat...
Reduced thioredoxin in both the cytosol and mitochondria: a key modulator of age-related cancer development in Trx1KO x Trx2KO mice?
This proposal is prompted by our observation that the down-regulation of thioredoxin (Trx) in both the cytosol and mitochondria (Trx1KO x Trx2KO) in mice resulted in reduced sponta...
Developing improved guidelines for nursing home-associated viral respiratory infections: Learning from the COVID-19 experience
PROJECT SUMMARY/ABSTRACT The COVID-19 pandemic highlighted the vulnerability of the nearly 1.4 million nursing home (NH) residents to respiratory healthcare associated infections (...
Long-term Trauma Outcomes and Insurance Policy
PROJECT SUMMARY/ABSTRACT Though trauma is often considered an isolated disease process, advancements in acute care have shifted the burden of injury from the acute physiologic insu...
Neural control of coordinated eye movements
Project Summary / Abstract We look between targets located in the 3D visual environment by making disjunctive saccades that bring the target image onto both foveae. Each gaze shift...
Human and Translational Immunology Training Program
Project Summary Progress in translational immunology has created a new demand for training scientists with expertise in human immunology and with the skills to bring discoveries in...