Results for Environment
40,772 grants found
Showing 34,481 – 34,500 of 40,772 grants for "Environment"
Engineered microsystems to assess endothelial contribution to myeloproliferative neoplasm thrombosis
PROJECT ABSTRACT Thrombosis is the leading cause of mortality among patients with myeloproliferative neoplasms (MPNs). MPNs are characterized by excessive production of red blood c...
Outcomes and perspectives on treatment for critical limb ischemia in patients with end-stage renal disease
Project Summary/Abstract Amputation and mortality rates are extraordinarily high for patients living with both advanced peripheral arterial disease, or critical limb ischemia (CLI)...
Impact of the ESRD Treatment Choices Model on Home Dialysis Uptake and Disparities
PROJECT SUMMARY/ABSTRACT Dr. Sri Lekha Tummalapalli is a nephrologist and health services researcher whose long-term goal is to become a leading national expert studying healthcare...
Cannabinoid modulation of EV composition and function in HIV/SIV infection
Abstract Extracellular vesicles (EVs) are cargo carrying, quasi-nanovesicles that mediate intercellular communication. EVs are released by many cell types and are present in body f...
Optical control of endogeneous GPCR and G protein Signaling
Abstract Cells sense the extracellular environment primarily using G protein-coupled receptors (GPCRs). They represent the largest family of cell surface proteins and play key phys...
Understanding drug delivery through an integrated barcoding approach
Project Summary Despite being hailed as the “magic bullet” that would selectively target and cure cancer, only a handful of nanoparticles have been successfully translated to the c...
Validation of a pediatric thrombosis risk assessment model and characterization of bleeding in hospitalized children through the Children's Hospital Acquired Thrombosis (CHAT) Consortium
PROJECT SUMMARY/ABSTRACT Venous thromboembolism (VTE), a serious and life-threatening condition, has increased in incidence for hospitalized pediatric patients by 70-200%. This has...
Optical control of endogeneous GPCR and G protein Signaling
Abstract Cells sense the extracellular environment primarily using G protein-coupled receptors (GPCRs). They represent the largest family of cell surface proteins and play key phys...
A translational bioinformatics approach to elucidate and mitigate polypharmacy induced adverse drug reactions
PROJECT SUMMARY This proposal for a mentored career development award consists of a training and research plan to facilitate Dr. Zackary Falls' transition to an independent in...
Intravascular microstructural, chemical and biomechanical characterization of coronary plaques
Heart disease is the leading cause of death in the US; the most prevalent type of heart disease is caused by atherosclerosis, the thickening of the vessel wall and creation of athe...
Effects of GLP-1 Receptor Agonists on Airway Inflammation and Platelet Activation in Asthma
PROJECT SUMMARY/ABSTRACT Despite the high prevalence of metabolic dysregulation among patients with asthma, precise mechanisms driving airway inflammation in this population are no...
Role of FAT1 somatic mutations in aggressiveness of head and neck cancer
PROJECT SUMMARY This proposed R03 application responds to NIDCR PAR-20-046 announcement entitled “NIDCR Small Research Grants for Analyses of Existing Genomics Data”. The project a...
Acupuncture for Cognitive Health in Older Survivors of Prostate Cancer (ACHIEVE)
PROJECT SUMMARY This career development award, Acupuncture for Cognitive Health in Older Survivors of Prostate Cancer (ACHIEVE), will train Dr. Liou to become an independent clinic...
Implementation of evidence-based strategies to optimize HPV vaccination in rural primary care settings
ABSTRACT Some of the largest disparities in human papillomavirus vaccination (HPVV) rates exist in rural communities, which represent missed opportunities for cancer prevention sin...
The structural underpinnings of disinhibition in dystonia
PROJECT SUMMARY / ABSTRACT Dystonia is a brain-based disorder that leads affected muscles to twist and spasm, contorting the sufferer into painful and disabling positions. Dystonia...
The structural underpinnings of disinhibition in dystonia
PROJECT SUMMARY / ABSTRACT Dystonia is a brain-based disorder that leads affected muscles to twist and spasm, contorting the sufferer into painful and disabling positions. Dystonia...
Implementation of evidence-based strategies to optimize HPV vaccination in rural primary care settings
ABSTRACT Some of the largest disparities in human papillomavirus vaccination (HPVV) rates exist in rural communities, which represent missed opportunities for cancer prevention sin...
Implementation of evidence-based strategies to optimize HPV vaccination in rural primary care settings
ABSTRACT Some of the largest disparities in human papillomavirus vaccination (HPVV) rates exist in rural communities, which represent missed opportunities for cancer prevention sin...
The structural underpinnings of disinhibition in dystonia
PROJECT SUMMARY / ABSTRACT Dystonia is a brain-based disorder that leads affected muscles to twist and spasm, contorting the sufferer into painful and disabling positions. Dystonia...
Novel Quality Measures for Primary Care Management of Attention-Deficit/Hyperactivity Disorder
PROJECT SUMMARY / ABSTRACT Attention-Deficit/Hyperactivity Disorder (ADHD) affects 8-10% of US children. Primary care providers (PCPs) care for most children with ADHD but quality...