Results for Environment
40,772 grants found
Showing 34,281 – 34,300 of 40,772 grants for "Environment"
T cell invasion of the stem cell compartment during immune-mediated GI damage
Despite the importance of intestinal stem cells (ISCs) for epithelial maintenance in the gastrointestinal (GI) tract and the clinical significance of inflammatory intestinal disord...
Genetic determinants of thoracic aortic stiffness and remodeling
Project Summary / Abstract This is an application for a K24 mentoring award for patient-oriented research (POR) from Julio Chirinos, MD, PhD, Associate Professor of Medicine at the...
The design and evaluation of strategies to implement HIV prevention interventions for pregnant women in community pharmacy settings
PROJECT SUMMARY: Pregnant women in high HIV-burden settings such as western Kenya are at increased risk of acquiring HIV infection during pregnancy. The World Health Organization (...
Traditional healer-initiated HIV counseling and testing in rural South Africa
Project Summary In South Africa, HIV testing has been undermined by HIV stigma, distrust in the allopathic health system, a preference for traditional medicine, and distance to the...
Unraveling strain-level variation in the induction of anti-inflammatory responses in the intestine
PROJECT SUMMARY: Inflammatory bowel disease (IBD) is an increasingly prevalent disease that currently affects ~1.3% of adults in the US.IBD is characterized by chronic inflammatory...
Genetic determinants of thoracic aortic stiffness and remodeling
Project Summary / Abstract This is an application for a K24 mentoring award for patient-oriented research (POR) from Julio Chirinos, MD, PhD, Associate Professor of Medicine at the...
Telehealth to Improve Prevention of Suicide (TIPS) in EDs
ABSTRACT Significance: Our study will rigorously evaluate whether synchronous, within-visit telemental health evaluation and intervention services can successfully overcome poor ac...
Genetic determinants of thoracic aortic stiffness and remodeling
Project Summary / Abstract This is an application for a K24 mentoring award for patient-oriented research (POR) from Julio Chirinos, MD, PhD, Associate Professor of Medicine at the...
Elucidating Oncogenic Mechanisms Underlying Wilms Tumor Using Kidney Organoids
PROJECT SUMMARY/ABSTRACT Wilms tumor is the most common pediatric kidney cancer. Blastemal-predominant tumors are classified as high-risk and have demonstrated resistance to chemot...
Dynamics, Regulation and Function of p53 in Single Cells
The dynamics of signaling systems are critical for controlling gene expression programs and cellular outcomes. The tumor suppressor protein p53 is a transcription factor orchestrat...
Unraveling strain-level variation in the induction of anti-inflammatory responses in the intestine
PROJECT SUMMARY: Inflammatory bowel disease (IBD) is an increasingly prevalent disease that currently affects ~1.3% of adults in the US. IBD is characterized by chronic inflammator...
T cell invasion of the stem cell compartment during immune-mediated GI damage
Despite the importance of intestinal stem cells (ISCs) for epithelial maintenance in the gastrointestinal (GI) tract and the clinical significance of inflammatory intestinal disord...
Dynamics, Regulation and Function of p53 in Single Cells
The dynamics of signaling systems are critical for controlling gene expression programs and cellular outcomes. The tumor suppressor protein p53 is a transcription factor orchestrat...
Dynamics, Regulation and Function of p53 in Single Cells
The dynamics of signaling systems are critical for controlling gene expression programs and cellular outcomes.The tumor suppressor protein p53 is a transcription factor orchestrati...
Determining the effects of Sox9 on the cell cycle of intestinal stem cells
Project Summary/Abstract The intestinal crypt houses diverse proliferative cells including highly proliferative Transit Amplifying cells, less proliferative active intestinal stem...
Imaging Modulation of Immune Phenotype
Imaging and modulation of immunophenotype Most importantly, we have created TLR delivery nanotherapeutics and find that TLR NPs combined with aCD40, aPD-1 and aCTL4 (abbreviated as...
Dysregulation of Liver Macrophages in Pancreatic Cancer
PROJECT SUMMARY Pancreatic ductal adenocarcinoma (PDAC) is the third-leading cause of cancer-related deaths in the United States. Metastasis is the major cause of mortality for pat...
NSF INCLUDES Planning Grant: 331 STEM:Energy 3 Universities, in 3 Cities, 1 Vision
This NSF INCLUDES planning grant is funded by NSF Inclusion across the Nation of Communities of Learners of Underrepresented Discoverers in Engineering and Science (NSF INCLUDES),...
Optical control of endogenous G protein Coupled Receptor and G Protein Signaling.
Abstract Cells sense the extracellular environment primarily using G protein-coupled receptors (GPCRs). They represent the largest family of cell surface proteins and play key phys...
Determining the Effectiveness of Live Coding on Student Learning in Introductory Programming
This project aims to serve the national interest by increasing the success of students in introductory programming courses. Teaching students how to program remains a significant c...