Results for Environment
40,772 grants found
Showing 34,121 – 34,140 of 40,772 grants for "Environment"
Pathogenesis of Heart Failure with Preserved Ejection Fraction in Chronic Kidney Disease
Project Summary Rupal Mehta, MD is an Assistant Professor of Medicine in the Division of Nephrology and Hypertension at the Northwestern University (NU) Feinberg School of Medicine...
Role of glycosylation in environmental and genetic schizophrenia risk
DESCRIPTION (provided by applicant): Manganese (Mn) is an essential metal required for normal neural development and function; however, at elevated levels, it is neurotoxic. Adults...
Calprotectin-mediated CD69 signaling in periodontitis
7. PROJECT SUMMARY / ABSTRACT Periodontitis is a chronic inflammatory condition characterized by the destruction of the periodontium and is theleading cause of tooth loss in adults...
Molecular Mechanisms of Reactive Epithelial Changes in Pediatric Eosinophilic Esophagitis
PROJECT SUMMARY Eosinophilic esophagitis (EoE) is a newly described immune-mediated disease and a leading cause of esophageal morbidity in children and young adults. Histologically...
Mechanisms for the regulation of novel lipids in vivo
Project Summary/Abstract: Research: Insulin resistance is a major cause for type 2 Diabetes (T2D) and is implicated in many life- threatening complications of T2D. A better underst...
Pathogenesis of Heart Failure with Preserved Ejection Fraction in Chronic Kidney Disease
Project Summary Rupal Mehta, MD is an Assistant Professor of Medicine in the Division of Nephrology and Hypertension at the Northwestern University (NU) Feinberg School of Medicine...
Molecular Mechanisms of Reactive Epithelial Changes in Pediatric Eosinophilic Esophagitis
PROJECT SUMMARY Eosinophilic esophagitis (EoE) is a newly described immune-mediated disease and a leading cause of esophageal morbidity in children and young adults. Histologically...
Mechanisms for the regulation of novel lipids in vivo
Project Summary/Abstract: Research: Insulin resistance is a major cause for type 2 Diabetes (T2D) and is implicated in many life- threatening complications of T2D. A better underst...
Hybrid Methods for Dynamic Structure Analysis of Proteins from Pathogenic Microorganisms
PROJECT SUMMARY This research program will investigate the general hypothesis that understanding the conformational diversity of proteins will provide new insights into their biolo...
University of Texas Southwestern - Stimulating Access to Research in Residency (UT-StARR) Program
Project Abstract Despite decades of research in the understanding and treatment of diseases of the heart and lung, cardiovascular and pulmonary diseases remain the leading causes o...
Regulation of hemoglobin production in normal and disease states
PROJECT SUMMARY / ABSTRACT Reversing the developmental switch from fetal (HbF) to adult hemoglobin is an important therapeutic approach in sickle cell disease (SCD). HbF expression...
Hybrid Methods for Dynamic Structure Analysis of Proteins from Pathogenic Microorganisms
PROJECT SUMMARY This research program will investigate the general hypothesis that understanding the conformational diversity of proteins will provide new insights into their biolo...
Modifying fragility fracture healing using a gradient-based mechanotransduction fixation approach
PROJECT SUMMARY Candidate: Dr. Hast received his bachelor's degree in mechanical engineering with a focus on thermodynamics and a Ph.D. in mechanical engineering with a focus...
Study to Explore Early Development (SEED) Follow up Studies, Components A, B, D & E
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that impacts approximately 1.5% of children in the United States. Individuals with ASD experience deficits in social...
Training Program in Translational Research
Abstract The Training Program in Translational Research offers an interdisciplinary program of study and research that prepares graduate students for successful careers at the inte...
Biomedical Informatics and Data Science Training Program (BIDS-TP)
This is a new application to support a novel Biomedical Informatics and Data Science Training Program (BIDS-TP) at the University of Michigan (UM). The overarching goal of the BIDS...
University of Texas Southwestern - Stimulating Access to Research in Residency (UT-StARR) Program
Project Abstract Despite decades of research in the understanding and treatment of diseases of the heart and lung, cardiovascular and pulmonary diseases remain the leading causes o...
RNA Methylation in Cancer Plasticity and Drug Resistance
PROJECT SUMMARY/ ABSTRACT Cancer drug resistance occurs not only by selection of genetically resistant clones, but also through phenotypic plasticity via rapid induction of transcr...
Advanced Training at the Interface of Engineering and Oral-Craniofacial Sciences
Oral diseases and disorders in the craniofacial complex disproportionally and devastatingly afflict susceptible populations, particularly impoverished families and medically or phy...
Advanced Training at the Interface of Engineering and Oral-Craniofacial Sciences
Oral diseases and disorders in the craniofacial complex disproportionally and devastatingly afflict susceptible populations, particularly impoverished families and medically or phy...