Results for Environment
40,772 grants found
Showing 33,801 – 33,820 of 40,772 grants for "Environment"
Impact of membrane composition on cholecystokinin receptor structure and function
PROJECT SUMMARY/ABSTRACT Cholecystokinin acts on type 1 receptors (CCK1Rs) present on vagal afferent neurons to regulate satiety, important in prevention and treatment of obesity....
Defining Host-pathogen Interactions in CAUTI to Guide Novel Drug Development
PPROJECT ABSTRACT More than 30 million urinary catheters (UCs) are placed every year in the US, making them the most commonly used indwelling medical device. While short-term UC us...
Optimizing Respiratory Culture Practices for Mechanically Ventilated Children
Brief Summary The number of mechanically ventilated children has grown 80-fold since the 1990s and ventilator- associated infections (VAIs) are a leading complication. In the absen...
Mixed methods research to increase engagement and smoking abstinence among African Americans enrolled in Quitline text messaging services
Project Summary/Abstract Cigarettes are used by over 34 million U.S. adults and cause more than 480,000 deaths annually due to smoking and smoke exposure. Despite smoking at simila...
Behavioral and Neural Substrates of Odor-Guided Navigation in the Human Brain
ABSTRACT Sensory systems have evolved to help meet the behavioral needs of organisms to ensure survival. Across the animal kingdom, two sensory functions are paramount: first, to i...
Understanding the predeterminants of transcription factor regulatory activity
PROJECT SUMMARY / ABSTRACT The goal of my research program is to understand how transcription factors (TFs) direct the regulatory programs that underlie cell fate decisions. My lab...
FW-HTF-P/Collaborative Research: Designing a Market-based Optimization Tool for the Future of Work: Balancing Remote Work and Community Vitality in Post-COVID American Cities
Remote work practices, which have been greatly accelerated due to the COVID-19 pandemic, will likely play an increased role in post-pandemic work and life for many businesses and t...
The Development and Evaluation of a Community-Based, Early Palliative Care Intervention for Black Women with Metastatic Breast Cancer
PROJECT SUMMARY/ABSTRACT Research: Early palliative care (PC) for patients with advanced cancer is an understudied area of health equity. Black women with metastatic breast cancer...
Effects of geospatial factors and health worker characteristics on child health: implications for interventions in low-resource settings
The career goal of the investigator is to become an independent epidemiologist at an academic institution and utilize a multidisciplinary framework to research and design intervent...
Integrated analyses of the epigenome to understand the molecular basis of hematopoietic malignancies
PROJECT SUMMARY Research Plan: An impaired hematopoietic differentiation process underlies bone marrow malignancies like leukemia, but we still lack the mechanistic understanding o...
Uncovering Epigenetic and Transcriptional Drivers of Neuroendocrine Plasticity at Single-Cell Level in Patients with Small Cell Lung Cancer Transformation
PROJECT SUMMARY/ABSTRACT Research: In lung adenocarcinoma (LUAD), neuroendocrine (NE) transformation to small cell lung cancer (SCLC) is associated with metastasis and resistance t...
Mechanisms of Atherogenesis in Clonal Hematopoiesis
1 Clonal hematopoiesis (CH), a highly prevalent condition in the elderly, arises from somatic mutations that endow2 a proliferative advantage to a subset of hematopoietic cells. CH...
The Development and Evaluation of a Community-Based, Early Palliative Care Intervention for Black Women with Metastatic Breast Cancer
PROJECT SUMMARY/ABSTRACT Research: Early palliative care (PC) for patients with advanced cancer is an understudied area of health equity. Black women with metastatic breast cancer...
Collaborative Research: DMREF: Designer 3D Mesoscale Materials Synthesized in the Self-Assembly Foundry
Self-assembly is one of the most promising avenues for the manufacturing/synthesis of materials and systems with exquisite control over nanoscale features while being fast, scalabl...
CAREER: Mechanics of Next-Generation Composites using Cellulose and Bioinspired Interfaces
This Faculty Early Career Development (CAREER) grant will lay the research and educational foundations to usher plant-inspired design to address challenges for next-generation comp...
RUI: The role of ecological memory in nearshore seagrass beds affected by multiple stressors
This award is funded in whole or in part under the American Rescue Plan Act of 2021 (Public Law 117-2).This project seeks to determine how ecological memory, shaped by an extreme d...
Collaborative Research: Ecological legacy effects of megacarcasses in African savanna ecosystems
Large animals such as elephants and rhinoceros, called ‘megafauna’ for their extreme size, have outsized impacts on the ecosystems they live in. They engineer their environments by...
Collaborative Research: DMREF: Designer 3D Mesoscale Materials Synthesized in the Self-Assembly Foundry
Self-assembly is one of the most promising avenues for the manufacturing/synthesis of materials and systems with exquisite control over nanoscale features while being fast, scalabl...
RII Track-2 FEC - Advanced Manufacturing of Renewable and Recyclable Polymers
Millions of tons of plastic waste pollute the environment with adverse ecological and health impacts. New technologies are urgently needed to facilitate plastic recycling and enabl...
CRCNS Research Project: Collaborative Research: Experimental, Numerical, and Robotic Study of the Role of Dynamic Load Sensing in Legged Locomotion
Insects are highly mobile walkers who adapt their muscle output to their ever‐changing environment. Force sensors in their legs detect increasing and decreasing forces, which may h...