Results for Environment
40,772 grants found
Showing 33,541 – 33,560 of 40,772 grants for "Environment"
Caenorhabditis Elegans: a Model for Genetic Interaction between the Gut Microbiota and Intestinal Epithelial Cells
Project Summary Inflammatory and infectious diseases are among the leading causes of death worldwide. Coordination and regulation of immune defenses are essential to combating infe...
Elucidating the gene regulatory networks that drive neural regeneration
Project Summary / Abstract There are no effective treatments to replace damaged retinal neurons, reflecting a fundamental inability for humans to mount robust regenerative response...
Immune profiling to detect viral hepatitis-related liver cancer in HIV-infected patients
Hepatocellular carcinoma (HCC) is the most frequent malignancy of the liver and the second most common cause of cancer-related death worldwide. HCC occurs in the setting of chronic...
Caenorhabditis Elegans: a Model for Genetic Interaction between the Gut Microbiota and Intestinal Epithelial Cells
Project Summary Inflammatory and infectious diseases are among the leading causes of death worldwide. Coordination and regulation of immune defenses are essential to combating infe...
A Novel Immunologically Directed Probiotic for the Treatment of Type 1 Diabetes
Project Summary Our goal is to develop a novel, immunologically-directed L. lactis probiotic-based therapeutic for the treatment of Type 1 Diabetes (T1D)1. T1D is a devastating dis...
Syntactic control of lexical activation during speech production - Resubmission - 1
Project Summary/Abstract Language is a defining feature of being human. No other animal has the ability to systematically order words or signs so as to communicate complex thoughts...
Augmented Reality as an Adjunct to Quitline Counseling for Smoking Cessation
PROJECT SUMMARY/ABSTRACT Cigarette smoking remains the leading preventable cause of morbidity and mortality in the United States. Developing effective cessation interventions remai...
Addressing arm non-use by encouraging idle-time activity during early recovery from stroke
Many survivors of stroke habitually refrain from using their more-involved arm during common daily activities despite retaining sufficient motor capability to perform movements. Th...
Microbial drivers of metabolically unhealthy obese phenotype
PROJECT SUMMARY This application for the Mentored Research Scientist Development Award will facilitate the principal investigator (PI)’s transition to independence dissecting host-...
TBI-induced adenosinergic dysregulation causes cognitive impairment and accelerates Alzheimer's disease pathology
Project Summary Epidemiological studies have revealed traumatic brain injury (TBI) as an important risk factor for development of Alzheimer’s disease (AD), a progressive neurodegen...
A fortified lipid bilayer platform for improved drug packaging and therapeutic delivery
Liposome, composed of a lipid bilayer comprising phospholipids (PL) and sterols such as cholesterol (Chol), has been extensively used for packaging and delivery of therapeutic agen...
A fortified lipid bilayer platform for improved drug packaging and therapeutic delivery
Liposome, composed of a lipid bilayer comprising phospholipids (PL) and sterols such as cholesterol (Chol), has been extensively used for packaging and delivery of therapeutic agen...
RM1 Center on Macromolecular Dynamics by NMR Spectroscopy at the New York Structural Biology Center (CoMD/NMR)
This proposal describes the mission and strategic plans for of a Biomedical Technology Development and Dissemination Center (RM1) entitled Center on Macromolecular Dynamics by NMR...
A Novel Intervention for Avoidance-Related Opioid Misuse in Patients with Cancer
Project Summary/Abstract Between 18% and 56% of patients with cancer misuse opioids. Opioid misuse can result in worse healthcare outcomes, such as neurotoxicity, infection, and co...
The role of ubiquitin in GPCR signaling
ABSTRACT The G protein-coupled receptor (GPCR) C-X-C chemokine receptor 4 (CXCR4) and its cognate ligand CXCL12 have been linked to endothelial cell migration, a necessary part of...
Training Program in Translational Science, HIV, and Sexual and Gender Minority Health
Project Summary Sexual and gender minorities (SGM) are heavily burdened by HIV in the U.S., including cisgender sexual minority men, transgender women and men, and non-binary peopl...
Pan-cancer genomic characterization of human papillomavirus associated tumors
PROJECT SUMMARY/ABSTRACT Human papilloma virus (HPV) infection causes an estimated 610,000 human cancers globally every year. HPV accounts for nearly all cervical and anal squamous...
Simultaneous prenatal alcohol and cannabinoid exposure & offspring corticostriatal neurocircuitry
PROJECT SUMMARY Prenatal alcohol exposure (PAE) is the most common cause of developmental disorders, though concurrent exposure to other psychoactive substances may exacerbate adve...
CRII: FRR: Semantic Vector Fields for Robot Navigation and Exploration in Unstructured Environments
To achieve greater mobility and autonomy for robots, it is important to study robust perception and navigation algorithms that can operate well not just with paved surfaces but als...
EAGER: Automatic Story Generation in Support of Early Vocabulary Learning
In child development, small early differences can compound into big long-term effects. One example of this is the relationship between early vocabulary size, literacy, and later ac...