Results for Environment
40,772 grants found
Showing 33,381 – 33,400 of 40,772 grants for "Environment"
Endometrial immune microenvironment dysfunction in endometriosis pathobiology
PROJECT SUMMARY Endometriosis, a debilitating chronic disease, affects around 10% of reproductive age women worldwide, severely impacting quality-of-life. Unfortunately, there is o...
Individually Measured Endophenotypes to Advance Computational Translation in Mental Health
Stress-related psychiatric disorders (SRPDs) are now the leading disease burden worldwide and diagnoses are increasing in both adolescents and adults. High rates of trauma in the U...
Neural population dynamics underlying flexibility in natural communication behaviors
PROJECT SUMMARY A central problem in neuroscience is to understand how the brain controls innate behaviors. While reductionist experiments have been invaluable in isolating specifi...
Multi-level mechanisms and predictors of irritability: An innovative approach bridging laboratory and real-world measures
PROJECT SUMMARY/ABSTRACT Irritability, an increased propensity to experience anger and frustration, is among the most common presenting complaints in child psychiatry. Severe irrit...
Systems Biology and Multi-Omics Core (SBMO)
PROJECT SUMMARY/ABSTRACT The overall goal of the Systems Biology and Multi-Omics Core (SBMOC, Core C) is to establish local infrastructure in the Indiana Center for Musculoskeletal...
Social Comparison on Social Media, Depressive Symptoms, and Body Dissatisfaction among Adolescents
PROJECT SUMMARY Social media (SM) has played an increasingly prominent role in adolescents’ daily lives over the past decade, notably coinciding with increased population prevalenc...
Delineating the mechanisms of filopodia-mediated intracellular delivery of siRNAs via peptide carriers towards the development of a molecular targeted therapy for oral cancer
The use of exogenous nucleic acids has great potential for therapeutic applications in numerous diseases, including cancer. However, the delivery of nucleic acids is challenging, a...
Flexible, scalable, and generalizable photogrammetric head modeling for high-density diffuse optical tomography
Project Summary: EsperImage, a startup company out of Washington University (WUSTL), will develop efficient and flexible data registration and modeling procedures to complement the...
Applying a Targeted Machine Learning and Causal Inference Approach to Analyzing Long-Term Sequelae of COVID-19 Infection Through the National COVID Cohort Collaborative.
PROJECT SUMMARY / ABSTRACT Candidate: I am an epidemiologist in the Division of Biostatistics at the University of California, Berkeley School of Public Health, and I completed my...
Environmental and social determinants of mammographic features
Percent mammographic density (PMD) is one of the strongest risk factors for, and is considered an intermediate marker of, breast cancer. Recent wide spread uptake of digital mammog...
Adolescent alcohol and cannabis transitions: Associations with multidimensional SES and cannabis policy
PROJECT SUMMARY/ABSTRACT Adolescents currently engaged in substance use often co-use (e.g., both alcohol and cannabis; AC co-use), yet few have systematically examined how youth AC...
Happiness and Pleasurable Activities as Longitudinal Predictors of Adolescent Alcohol and Cannabis Outcomes
Project Summary/Abstract Adolescence is the developmental period most strongly associated with the initiation and escalation of substance use, making it an ideal time to identify p...
Novel radiomic signatures for treatment response to neoadjuvant therapy in rectal cancers
ABSTRACT: With nearly 45,000 rectal cancers to be diagnosed in 2023, the major clinical question of interest is the identification of those patients who will achieve sustained clin...
Brain endothelial barrier disruption during cerebral malaria
Summary Cerebral malaria is a serious complication of Plasmodium falciparum infection where infected red blood cells (iRBC) adhere to brain endothelial cells, eventually leading to...
Conference: Student Participation Support for the 2024 North American Membrane Society (NAMS) Conference
This award will provide travel support for 24 U.S.-based undergraduate and graduate students to attend the 33rd Annual Meeting of the North American Membrane Society (NAMS). The me...
Neural circuit dynamics of spatial reward memory
Project Summary / Abstract Our strongest memories often stem from our most rewarding experiences, allowing us to learn what features of experience predict reward and to use these p...
Pancreatic fat and volume and childhood metabolic health
PROJECT SUMMARY/ABSTRACT The rise of type 2 diabetes (T2D) in U.S. youth is an alarming public health issue. Although obesity is a strong risk factor for pediatric T2D, at the same...
Defining the mechanisms of surgical site infection after oral cancer surgery using peri-operative metagenomics
Project Summary Oral cavity reconstruction (OCR), which involves open surgical resection of oral cancer with vascularized tissue flap reconstruction, remains a central component of...
Investigating the Role of MYC in Meibomian Gland Oncogenesis
PROJECT SUMMARY/ABSTRACT Sebaceous carcinomas (SebCA) of the ocular adnexa (OA) most frequently arise from the specialized sebaceous glands of the eyelid (Meibomian glands, MGs), a...
Rare Airway Cell Function in Post-Viral Chronic Inflammation
PROJECT SUMMARY The airway epithelium serves as a barrier between the aerosol environment and the underlying submucosa. Inhaled air often carries noxious agents and pathogens that...