Results for Environment
40,772 grants found
Showing 33,221 – 33,240 of 40,772 grants for "Environment"
Mount Sinai HHEAR Network Targeted Lab Hub
Overall PROJECT SUMMARY/ABSTRACT The Icahn School of Medicine at Mount Sinai will leverage our research expertise in environmental epidemiology, analytical chemistry and clinical p...
SPOT-IT: Sepsis Prediction in Oncology Through Implementation Science and Technology
Project Abstract Patients with cancer face unacceptable morbidity and mortality from sepsis, a life-threatening dysregulated response to infection. Oncologic sepsis contributes to...
Role of the Immune Response in Spiral Ganglion Neuron Death After Hair Cell Loss
Project Summary Sensorineural hearing loss, the most common form of hearing loss, is characterized by damage to inner ear sensory hair cells or to the spiral ganglion neurons (SGNs...
Molecular Biophysics Training Grant at Vanderbilt
The application of quantitative approaches to study biology and medicine is an essential underpinning for the advancement of biomedical research. This proposal requests support for...
Maturation, Germination, and Pathogenesis of Cryptococcus Spores
PROJECT SUMMARY/ABSTRACT Worldwide, over a billion people each year experience high morbidity and/or mortality from the effects of human fungal pathogens. People with AIDS, chemoth...
Uncovering therapeutic vulnerabilities in AML through mechanistic interrogation of MECOM activity
Project summary Despite recent progress in the understanding of the biological underpinnings of acute myeloid leukemia (AML) and advances in the treatment of patients with AML, few...
Elucidating the gene regulatory networks that drive neural regeneration
Project Summary / Abstract There are no effective treatments to replace damaged retinal neurons, reflecting a fundamental inability for humans to mount robust regenerative response...
1/2 Milrinone for Prevention of Post-Patent Ductus Arteriosus Closure Syndrome in Extremely Preterm Infants (MIDAS Trial) – CCC
PROJECT SUMMARY Significance: Prematurity a major health problem in the United States, with more than 385,000 babies born preterm annually. The economic cost is more than $50 billi...
Stanford Center for Clinical and Translational Research and Education
ABSTRACT The mission of the Stanford CTSA is to transform clinical, translational, and science of translation research and education (CTSRE) at Stanford and across the CTSA consort...
Quantitative Neuroscience Spanning Molecules, Cells, Circuits, and Behavior
PROJECT SUMMARY Quantitative research, when appropriately planned and executed, yields results that are objective, unbiased, and replicable across experimental systems and labs. Th...
GLUCOSE BINDS RBPs TO REGULATE EPIDERMAL HOMEOSTASIS
GLUCOSE BINDS RBPs TO REGULATE EPIDERMAL HOMEOSTASIS PROJECT SUMMARY/ABSTRACT One in four Americans are affected by skin disease, underscoring the importance of understanding the m...
Optimizing treatment decisions and quality-adjusted life years through improved lung cancer staging
PROJECT SUMMARY The number of patients with potentially curable, stage I-III non-small cell lung cancer (NSCLC) is increasing, and appropriate treatment selection depends upon the...
Personal Healthcare Networks of Transgender and Gender-Diverse Adults After Gender-Affirming Surgery
Transgender and gender-diverse (TGD) individuals face substantial health disparities compared to cisgender (i.e., non-TGD) people, including increased depression, anxiety, substanc...
Targeting hyper-reactive cysteines within PPI interfaces
Project Summary Protein-protein interactions (PPIs) are essential in cellular processes and human diseases. It is estimated that 80% of proteins rely on PPIs to perform their prima...
Examining how visual experience modulates the thalamus and visuomotor responses.
SUMMARY Vision is how most organisms perceive and respond to their environment, making the development and function of this sensory modality paramount. Visual experience is necessa...
Endoplasmic Reticulum Protein Homeostasis in Renal Physiology and Acute Kidney Injury
Acute kidney injury (AKI) is a life-threatening and costly condition, affecting ~15% of all hospitalized patients, including up to 65% of those requiring intensive care. Despite th...
NJ ACTS: A Platform for Translational Science in New Jersey: CTSA K12 Program at Rutgers, Biomedical Health Sciences
Project Summary/Abstract The objective of the New Jersey Alliance for Clinical and Translational Science (NJ ACTS) Institutional Career Development Award (K12), Doctors as Valued L...
Cardiovascular Research and Drug Development (CRDD) training program
PROJECT SUMMARY The mission of the ‘Cardiovascular Research and Drug Development’ (CRDD) training program at Baylor College of Medicine (BCM) is to train predoctoral (PhD and MD/Ph...
Long-term population-level impact of a school-based parenting-focused intervention to prevent obesity among Black and Latinx children in historically disinvested neighborhoods
Project Summary/ Abstract Children with obesity are at increased risk of cardiovascular disease, type 2 diabetes, and premature death. Black and Latinx children are more likely tha...
Mechanisms of membrane tethering in autophagy
Project Summary/Abstract Cells are in a constant battle to maintain homeostasis and respond to stress. Autophagy is a conserved eukaryotic pathway that responds to cellular stresse...