Results for Environment
40,772 grants found
Showing 33,081 – 33,100 of 40,772 grants for "Environment"
Conference: Scientific Assessment of the McMurdo Dry Valleys Ecosystem: Environmental Stewardship in a Time of Dynamic Change
Non-technical abstractThe McMurdo Dry Valleys are the largest ice-free area on the Antarctic continent and are a place where life exists at the very extremes of environmental and p...
BCOR/PRC1.1 Inactivation In Splicing Factor Mutant MDS Progression
PROJECT SUMMARY: Myeloid malignancy is characterized by the acquisition of mutations in a stereotyped order with distinct patterns of cooperating mutations. Mutations in genes that...
Commercial and Regulatory Development of an Enhanced Performance Hemodialysis Access Graft
PROJECT SUMMARY Objective: The goal of this SBIR CRP project is to move a novel hemodialysis access graft design through the major commercialization milestone of 510(k) submission....
Genetic risk and molecular characterization of Diabetic Kidney Disease
Diabetic kidney disease (DKD) is the leading cause of end-stage kidney failure in the USA and is increasing in prevalence at an alarming rate worldwide with no targeted therapy ava...
Targeting mitochondrial vulnerabilities to drive intrinsic melanoma immunogenicity
Project Summary: Immunotherapies have revolutionized the clinical treatment of melanoma; however, these treatment strategies have been ineffective in treating late stage and metast...
U-RISE at Sam Houston State University
PROJECT SUMMARY/ABSTRACT Underrepresentation of researchers from marginalized groups (racial, ethnic, disability, gender, economic, and geographic groups) is noteworthy in the Unit...
Scaling-up Medication for Opioid Use Disorder in Residential Treatment Settings
PROJECT SUMMARY/ABSTRACT Medications for opioid use disorder (MOUD; methadone, buprenorphine, naltrexone) are highly efficacious treatments for OUD; risk of fatal and nonfatal over...
De novo mutations in replication-independent histone genes and an unexplored class of rare pediatric mendelian syndromes
PROJECT SUMMARY Heterozygous germline missense mutations in replication-independent (RI) histones are emerging as the cause of histonopathies, a devastating class of pediatric neur...
Clinical Phenotyping and Molecular Integration Core
PROJECT SUMMARY Clinical Phenotyping and Molecular Integration Core (Core B) Our innovative application seeks to understand the how heterogeneity neutrophil populations in the lung...
Transcription Factors Overcoming Chromatin Barriers to Control Cell Fate
Project summary: The goal of this proposal is to reveal mechanisms by which gene regulatory proteins overcome chromosome structural barriers, to change cell fates. The work will pr...
Epigenetic Regulation of Langerhans Cell Histiocytosis Pathophysiology and Microenvironment by HDAC3
PROJECT SUMMARY/ABSTRACT Langerhans cell histiocytosis (LCH) is a rare inflammatory myeloid neoplasm with a wide range of clinical manifestations and severity caused by mutations t...
Neuronal control of cochlear stress responses
Project Summary Animals, including humans, navigate through a noisy environment that can damage the ear and elicit whole body changes in physiology and emotional state. The respons...
Near-infrared light controlled transplanted cells to treat spinal cord injury
PROJECT SUMMARY The goal of this project is to develop a prototype transplantation technology based on optogenetically controlled Schwann cells (SCs) and test its efficacy in a rat...
NSF PRFB FY 2023: Multi-omics Assessment of Translocation Impacts on Sonoran Pronghorn
This action funds an NSF Postdoctoral Research Fellowship in Biology for FY 2023, Integrative Research Investigating the Rules of Life Governing Interactions Between Genomes, Envir...
Training Program in the Biology of Aging and Lung Diseases
The lung is a major determinant of human health and respiratory diseases are a leading cause of morbidity and mortality among the elderly. The elderly population is one of the fast...
PixelPrint: a 3D printing platform for creating lifelike patient-based CT phantoms
Abstract. While CT remains the most highly utilized diagnostic tool in clinical practice, its technology still calls for research and development along the entire imaging chain to...
Defining Tumor Microenvironmental Interactions that drive THY1-Mediated Treatment Resistance in Glioblastoma
This K08 proposal will complete Dr. Wajd Al-Holou’s training towards his long-term career goal of directing an independent research program that aims to define critical cellular in...
Cellular and Molecular Mechanisms Underlying the Development of Brown Adipose Tissue
PROJECT SUMMARY: Obesity and its comorbidities pose an ever-increasing challenge to public health despite massive investments in pharmacologic, surgical, and lifestyle-modifying th...
2024 Intermediate Filaments Gordon Research Conference and Seminar
Summary Intermediate filament (IF) proteins are encoded by over 70 distinct genes, placing them among the largest gene families in humans. Members of the IF protein family have div...
2024 Neural Mechanisms of Acoustic Communication Gordon Research Conference and Seminar
Project Summary In its second installment, the Neural Mechanisms of Acoustic Communication (NMAC) Gordon Research Conference, which this year will also include an associated Gordon...