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Results for Environment

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Showing 32,92132,940 of 40,772 grants for "Environment"

Completed OTHER RESEARCH-RELATED
Primary care based collaborative approach to care management for older adults with dementia
NATIONAL INSTITUTE ON AGING Johns Hopkins University United States 2021 – 2026

Care for the growing population of older adults with Alzheimer's Disease and Related Dementias (ADRD) is challenging. Care management programs are a common approach to streaml...

$1.97M
USD
Completed NON-SBIR/STTR RPGS
Gene Edited and Engineered Tumor Cell Therapeutics for Cancer
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... Brigham and Women'S Hospital United States 2021 – 2026

SUMMARY Despite recent advances in therapeutic strategies, the prognosis for patients with highly malignant brain tumors, glioblastomas (GBM) remains poor, with a median survival o...

$4.42M
USD
Completed OTHER RESEARCH-RELATED
Primary care based collaborative approach to care management for older adults with dementia
NATIONAL INSTITUTE ON AGING Johns Hopkins University United States 2021 – 2026

Care for the growing population of older adults with Alzheimer's Disease and Related Dementias (ADRD) is challenging. Care management programs are a common approach to streaml...

$1.89M
USD
Completed NON-SBIR/STTR RPGS
It's a tug of war: structure, consequences, and inhibition of CXCR4 and ACKR3 responses to lymphocyte chemoattractant CXCL12
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of California, San Diego United States 2021 – 2026

The G protein-coupled chemokine receptor, CXCR4, and the atypical chemokine receptor, ACKR3, play critical roles in cell migration during immune responses and organ development, th...

$6.72M
USD
Completed NON-SBIR/STTR RPGS
Developmental Origin, Injury and Epigenomic Regulation of NF1-Associated Peripheral Nerve Sheath Tumors
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... Children'S Research Institute United States 2021 – 2026

Project Abstract Individuals with neurofibromatosis type 1 (NF1) have an approximately 160-fold increased risk of developing malignant peripheral nerve sheath tumor (MPNST). As a l...

$6.77M
USD
Completed OTHER RESEARCH-RELATED
Novel approaches to identify and quantify the impact of drug-drug interactions in older adults with diabetes, with a focus on multimorbidity and polypharmacy
NATIONAL INSTITUTE ON AGING Brigham and Women'S Hospital United States 2021 – 2026

PROJECT SUMMARY / ABSTRACT This application for a Mentored Research Scientist Development Award (K01) is submitted by Katsiaryna Bykov, PharmD, ScD, in response to PA-20-190. Dr. B...

$1.31M
USD
Completed NON-SBIR/STTR RPGS
Research Program on Cognition and Neuromodulation Based Interventions (RP-CNBI)
NATIONAL INSTITUTE ON AGING University of Michigan At Ann Arbor United States 2021 – 2026

Abstract Project description: The NIA’s Alzheimer’s disease and related dementia (ADRD) Milestone 8 focuses on the development and translation of non-pharmacologic interventions an...

$8.37M
USD
Active CONTINUING GRANT
CPS: Frontier: Collaborative Research: COALESCE: COntext Aware LEarning for Sustainable CybEr-Agricultural Systems
National Science Foundation (US Iowa State University United States 2021 – 2026

One of the grand technical challenges of our generation is to get ready to feed 9 billion people by 2050 with sustainable use of water and chemicals. However, we are facing unprece...

$52.36M
USD
Completed OTHER RESEARCH-RELATED
Novel approaches to identify and quantify the impact of drug-drug interactions in older adults with diabetes, with a focus on multimorbidity and polypharmacy
NATIONAL INSTITUTE ON AGING Brigham and Women'S Hospital United States 2021 – 2026

PROJECT SUMMARY / ABSTRACT This application for a Mentored Research Scientist Development Award (K01) is submitted by Katsiaryna Bykov, PharmD, ScD, in response to PA-20-190. Dr. B...

$1.31M
USD
Completed NON-SBIR/STTR RPGS
Gene Edited and Engineered Tumor Cell Therapeutics for Cancer
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... Brigham and Women'S Hospital United States 2021 – 2026

SUMMARY Despite recent advances in therapeutic strategies, the prognosis for patients with highly malignant brain tumors, glioblastomas (GBM) remains poor, with a median survival o...

$4.51M
USD
Completed OTHER RESEARCH-RELATED
Understanding the molecular mechanism of memory from single-cell gene expression to protein folding
NATIONAL INSTITUTE ON AGING University of Iowa United States 2021 – 2023

Project Summary / Abstract Deficits in cognitive function and memory are a debilitating aspect of neurodegenerative disease resulting in long-term disability, enormous suffering to...

$1.33M
USD
Completed NON-SBIR/STTR RPGS
The role of astrocyte-neuron signaling in closing a critical period required for motor circuit structure function and behavior
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... Washington University United States 2021 – 2025

PROJECT SUMMARY Significance: Neural circuit assembly requires activity-dependent refinement of circuit architecture (e.g. plasticity) to produce stereotyped behavior. Neurons are...

$2.49M
USD
Completed NON-SBIR/STTR RPGS
Gene Edited and Engineered Tumor Cell Therapeutics for Cancer
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... Brigham and Women'S Hospital United States 2021 – 2026

SUMMARY Despite recent advances in therapeutic strategies, the prognosis for patients with highly malignant brain tumors, glioblastomas (GBM) remains poor, with a median survival o...

$4.02M
USD
Completed NON-SBIR/STTR RPGS
Developmental Origin, Injury and Epigenomic Regulation of NF1-Associated Peripheral Nerve Sheath Tumors
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... Children'S Research Institute United States 2021 – 2026

Project Abstract Individuals with neurofibromatosis type 1 (NF1) have an approximately 160-fold increased risk of developing malignant peripheral nerve sheath tumor (MPNST). As a l...

$6.47M
USD
Completed OTHER RESEARCH-RELATED
Novel approaches to identify and quantify the impact of drug-drug interactions in older adults with diabetes, with a focus on multimorbidity and polypharmacy
NATIONAL INSTITUTE ON AGING Brigham and Women'S Hospital United States 2021 – 2026

PROJECT SUMMARY / ABSTRACT This application for a Mentored Research Scientist Development Award (K01) is submitted by Katsiaryna Bykov, PharmD, ScD, in response to PA-20-190. Dr. B...

$1.31M
USD
Completed OTHER RESEARCH-RELATED
Primary care based collaborative approach to care management for older adults with dementia
NATIONAL INSTITUTE ON AGING Johns Hopkins University United States 2021 – 2026

Care for the growing population of older adults with Alzheimer's Disease and Related Dementias (ADRD) is challenging. Care management programs are a common approach to streaml...

$1.98M
USD
Completed NON-SBIR/STTR RPGS
Research Program on Cognition and Neuromodulation Based Interventions (RP-CNBI)
NATIONAL INSTITUTE ON AGING University of Michigan At Ann Arbor United States 2021 – 2026

Abstract Project description: The NIA’s Alzheimer’s disease and related dementia (ADRD) Milestone 8 focuses on the development and translation of non-pharmacologic interventions an...

$8.38M
USD
Completed NON-SBIR/STTR RPGS
Elucidating the structural determinants of odor specificity in insect olfactory receptors
NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICA... Harvard Medical School United States 2021 – 2025

Project Summary The sense of smell provides animals with vital information about their environment. At the molecular level, olfactory stimuli consist of thousands of distinct small...

$2.49M
USD
Completed NON-SBIR/STTR RPGS
Elucidating the structural determinants of odor specificity in insect olfactory receptors
NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICA... Harvard Medical School United States 2021 – 2025

Project Summary The sense of smell provides animals with vital information about their environment. At the molecular level, olfactory stimuli consist of thousands of distinct small...

$2.49M
USD
Completed NON-SBIR/STTR RPGS
Elucidating the structural determinants of odor specificity in insect olfactory receptors
NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICA... Harvard Medical School United States 2021 – 2025

Project Summary The sense of smell provides animals with vital information about their environment. At the molecular level, olfactory stimuli consist of thousands of distinct small...

$2.49M
USD