Results for Environment
40,772 grants found
Showing 32,881 – 32,900 of 40,772 grants for "Environment"
Development and Persistence of Tissue-Level Musculoskeletal Deformity Following Brachial Plexus Birth Injury
PROJECT SUMMARY Brachial plexus birth injury (BPBI) is a traumatic perinatal neuromuscular injury causing muscle paralysis and lifelong arm impairment. Muscle paralysis in these ch...
POST-TRANSCRIPTIONAL REGULATION OF CELL FATE IN EARLY MAMMALIAN DEVELOPMENT
Post-transcriptional regulation by RNA-binding proteins (RBPs) and microRNAs (miRNAs) orchestrate diverse molecular and cellular mechanisms that pattern early mammalian development...
Approach Bias Modification for Co-Occurring Cannabis and Alcohol Use among Treatment-Seeking Adolescents
PROJECT SUMMARY/ABSTRACT Alcohol and cannabis are the first and second most commonly used substances among adolescents. Adolescence is a period of considerable development, making...
Passive Assessment of Behavioral Warning Signs for Suicide Risk in Adolescents: An Idiographic Approach
PROJECT SUMMARY/ABSTRACT Suicide is the second leading cause of death among adolescents and the rates have doubled since 2000. The rise in suicide rates is due in part to a failure...
Behavioral Activation for Depression in Older Adult Cancer Survivors: Pilot Randomized Control Trial and Implementation Outcomes
Project Summary/Abstract: As many as 35% of older adult cancer survivors (OACS; ≥65-years, ≥1-year post- treatment) have clinically significant depression. Presently, 64% of cancer...
A Personalized, Patient-Centered Approach to Optimizing Lupus Care
Candidate: April Jorge, MD is an Instructor in Medicine at Harvard Medical School (HMS) and an Assistant in Medicine in the Rheumatology Unit at Massachusetts General Hospital (MGH...
Improving Medication Use and Outcomes in Older Adults with Dementia after Hospitalization: Effectiveness of Medicare Programs
PROJECT SUMMARY/ABSTRACT Hospitalizations and medication problems after discharge are a major risk factor for poor health outcomes in older adults with Alzheimer's disease and...
Understanding and improving responses to adaptive NK cell therapy for leukemia and multiple myeloma
Project Summary Natural killer (NK) cells are potent, effector lymphocytes with the ability to kill malignant and virally infected cells by releasing lytic granules without the nee...
Unraveling the molecular connections that link circadian rhythms and lipid metabolism
PROJECT SUMMARYMisalignments and disruption of the circadian clock lead to metabolic and physiological dysfunctions. The clock regulates metabolism whereas metabolic activities fee...
U-RISE at Texas State University
Project Summary/Abstract Texas State University (TxState) will implement an Undergraduate Research Training Initiative for Student Enhancement program (U-RISE Tx) to increase the d...
Regulation of Endometriotic Lesion Development by NOTCH1
Project Summary Endometriosis is a chronic, estrogen-dependent gynecological disorder affecting 10-15% of women of reproductive age resulting in pelvic pain and infertility. It is...
Identifying tobacco-genetic interactions through study of the aryl hydrocarbon receptor pathway.
Human exposure to environmental toxins such as those in tobacco related products are the leading cause of preventable deaths in the United States, with the greatest effect on morbi...
U-RISE at Claflin University through Collaborative Interdisciplinary Mentoring in Biomedical Sciences
7. Project Summary/Abstract Located in Orangeburg, South Carolina, Claflin University (CU), an independent, four-year, co-educational, residential, career-oriented liberal arts uni...
Project 3: MANCR Mediates Epigenetic Mechanisms for Survival of Advanced Breast Cancer
SUMMARY Long non-coding RNAs (lncRNAs) are epigenetic regulators of the chromatin organization supporting cancer cell activities. There is a gap in the literature identifying the c...
Duke Center for Advancement of Child Health (CAtCH)
The Child Health Research Career Development Award (CHRCDA) Program in the Department of Pediatrics at Duke University Medical Center, entitled Duke Center for Advancement of Child...
Genome-wide mechanisms and dynamics of ATP-dependent chromatin remodeling complexes
PROJECT SUMMARY/ABSTRACT The SWI/SNF family ATP-dependent chromatin remodelers are multi-subunit protein complexes that dynamically position chromosomal nucleosomes to modulate DNA...
Sleep Well, Bee Well: Sleep Health Promotion Intervention in Early Head Start
PROJECT SUMMARY Sleep deficiency in early childhood, including poorly timed sleep, inadequate sleep duration, and night awakenings, is associated with numerous health concerns such...
Unraveling the molecular connections that link circadian rhythms and lipid metabolism
PROJECT SUMMARYMisalignments and disruption of the circadian clock lead to metabolic and physiological dysfunctions. The clock regulates metabolism whereas metabolic activities fee...
Development and Persistence of Tissue-Level Musculoskeletal Deformity Following Brachial Plexus Birth Injury
PROJECT SUMMARY Brachial plexus birth injury (BPBI) is a traumatic perinatal neuromuscular injury causing muscle paralysis and lifelong arm impairment. Muscle paralysis in these ch...
Exploring the Ecological Role of Rothia mucilaginosa and It's Iron Binding Siderophore Enterobactin
Project Summary The oral cavity is a highly diverse microbial environment, consisting of >2000 bacterial, archaeal, and fungal species most of which have not been functionally c...