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Loneliness Across Time and Space
The places where people live and spend their time seem to matter for loneliness, but previous research provides mixed evidence for this link. The core argument of LOTIS is that to...
Unravelling the role of neuronal antibodies and innate immunity partnership in human autoimmune encephalitis
Autoimmune encephalitides (AE) are severe brain disorders mediated by antibodies against neuronal proteins, such as the N-Methyl-D-Aspartate receptor (NMDAR). The antibody effects...
Molecules as electronically open quantum systems
To control chemistry we must understand it, and this requires a fundamental quantum mechanical description. Today we have a highly mature state of accurate quantum chemical modelin...
Children as Agents of Cultural Evolution
Cultural evolutionary theory is quickly gaining traction as a unifying framework for the social sciences. However, research into culture acquisition paints a picture of children as...
Functional Microscopy of Individual Neurons in the Living Human Retina
Subcellular, functional imaging of neurons in living humans could revolutionize biomedical research and prove valuable in the clinic. With optical techniques, subcellular resolutio...
Targeting tertiary lymphoid structures using magneto-margination
Tertiary lymphoid structures (TLS) are ectopic lymphoid tissues that drive immune responses at sites of chronic inflammation. They are of widespread interest in biology and medicin...
Heterochromatin repair: mechanisms and roles across scales
Cells face continuous challenges from insults that damage their DNA. To safeguard DNA integrity, a range of repair mechanisms have evolved, which are crucial for organismal surviva...
Predictive algorithms for simulating quantum materials
This project seeks to advance the field of predictive algorithms for quantum many-body systems by developing a next-generation numerical toolset. The project will focus on combinin...
Carboxylic acids as REAcTIVE refrigerants to make heat pumps efficient
Aiming to contribute to a substantial increase in the sustainability of thermal power plants, heat pumps, and climatization systems, the ERC-StG-REACHER is introducing new working...
Magneto-ionic data-security device integrated on flexible substrates
Traditional methods of safeguarding data often fall short in today’s rapidly evolving information technology landscape. Passwords are vulnerable to hacking, and while encryption of...
Deciphering Alzheimer’s disease molecular subtypes to advance treatment development.
Worldwide, 50 million people suffer from dementia, which is caused by Alzheimer’s disease (AD) in 70% of the cases. There is no treatment to stop, reverse or prevent AD. AD is path...
Data Governance for Equitable and Sustainable Digital Food Systems
Across the world, digitalization has been heralded as the start of a new ""agricultural revolution."" Data collected from digital sensors implanted into soil, satellites, and mobil...
Mucociliary adaptations and gut microbiome establishment in Xenopus
Cell type compositions determine tissue morphologies and functions, are adapted during evolution, and their changes cause diseases. However, we do not understand how cell type comp...
Thermal Conversion and Storage in One Solid-State Device
Waste heat makes up a very large fraction of the energy produced today. The process chain of energy conversion of chemical energy into power is subject to up to 72% loss. Recoverin...
Flexible Attosecond Soliton Transients for Extreme Resolution
Ultrafast laser pulses allow us to follow fundamental processes such as chemical reactions and electron transport at their natural timescale. Because optical (ultraviolet, visible...
Multiscale modelling of aberrant phase transitions in biocondensates
The spatiotemporal organization of the cell material represents one of the great wonders in physics, chemistry and biology. Compartmentalization plays a key role in such precise mo...
Re-cleaneable SERS devices for Personalised Health and Environmental sensing
We have invented an optical enhancement technique based on surface-enhanced Raman scattering (SERS) using self-assembled gold nanostructures that can fingerprint a wide range of bi...
Unraveling the regulation of crossover formation from its in vivo dynamics
The formation of crossovers during meiotic cell divisions is a crucial process to produce sperm and egg cells. This mechanism not only secures proper chromosome segregation but als...
Sustainable and Collaborative Research Information for Bibliodiverse Ecosystems: A Transnational Study
This project aims to understand the conceptualisation of open in the open access movement and the development of open research infrastructure from a transnational perspective by id...
Reinventing Multiterminal Coding for Intelligent Machines
Advancements in sensors and deep learning have elevated the perception capacity of machines, bringing mid-level autonomy within reach. However, the abundance of high-dimensional da...