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FAST-FNA immune cell profiling in HNSCC
Currently, the single best predictive biomarker of response to anti-PD1 monotherapy is PD-L1 expression as assessed by immunohistochemical staining of archived or fresh tissue. Cur...
FAST-FNA immune cell profiling in HNSCC
Currently, the single best predictive biomarker of response to anti-PD1 monotherapy is PD-L1 expression as assessed by immunohistochemical staining of archived or fresh tissue. Cur...
FAST-FNA immune cell profiling in HNSCC
Currently, the single best predictive biomarker of response to anti-PD1 monotherapy is PD-L1 expression as assessed by immunohistochemical staining of archived or fresh tissue. Cur...
Admin. Supp. for NCI P30 Cancer Center Grants to Facilitate the Development of Standardized Electronic Treatment Plan Builds for NCI-Supported Clinical Trials Applicable Across Clinical Research Sites
PROJECT SUMMARY Electronic health records (EHR) are used in all NCI-supported Cancer Centers.EHR data support not only the delivery of standard-of-care treatments, but also investi...
Identification of Genes and DNA Methylation Markers for Lung Cancer Risk by Integrating Multi-omics Data
Project Summary Lung cancer is the leading cause of cancer death in the United States and many other countries. Genome-wide association studies (GWAS) have identified ~55 genetic l...
TOPIC 382 - INTEGRATED IMAGING AND MOLECULAR ANALYSIS OF GLIOBLASTOMA USING SCOPE SEQ ON THE AIR FLOW
Clinical research is incorporating single cell analysis methods into various evaluations.During 75N91019C00029 (Phase I) of this proposed program, we intended to validate the perfo...
Identification of Genes and DNA Methylation Markers for Lung Cancer Risk by Integrating Multi-omics Data
Project Summary Lung cancer is the leading cause of cancer death in the United States and many other countries. Genome-wide association studies (GWAS) have identified ~55 genetic l...
Identification of Genes and DNA Methylation Markers for Lung Cancer Risk by Integrating Multi-omics Data
Project Summary Lung cancer is the leading cause of cancer death in the United States and many other countries. Genome-wide association studies (GWAS) have identified ~55 genetic l...
Identification of Genes and DNA Methylation Markers for Lung Cancer Risk by Integrating Multi-omics Data
Project Summary Lung cancer is the leading cause of cancer death in the United States and many other countries. Genome-wide association studies (GWAS) have identified ~55 genetic l...
Combining Irreversible Electroporation with Immunotherapy for the Systemic Treatment of Pancreatic Cancer
Abstract The goal of cancer immunotherapy is to utilize the patient’s immune system to reject the invading “foreign” tumor. However, the pancreatic cancer microenvironment is chara...
Combining Irreversible Electroporation with Immunotherapy for the Systemic Treatment of Pancreatic Cancer
Abstract The goal of cancer immunotherapy is to utilize the patient’s immune system to reject the invading “foreign” tumor. However, the pancreatic cancer microenvironment is chara...
Combining Irreversible Electroporation with Immunotherapy for the Systemic Treatment of Pancreatic Cancer
Abstract The goal of cancer immunotherapy is to utilize the patient’s immune system to reject the invading “foreign” tumor. However, the pancreatic cancer microenvironment is chara...
Combining Irreversible Electroporation with Immunotherapy for the Systemic Treatment of Pancreatic Cancer
Abstract The goal of cancer immunotherapy is to utilize the patient?s immune system to reject the invading ?foreign? tumor.However, the pancreatic cancer microenvironment is charac...
Combining Irreversible Electroporation with Immunotherapy for the Systemic Treatment of Pancreatic Cancer
Abstract The goal of cancer immunotherapy is to utilize the patient’s immune system to reject the invading “foreign” tumor. However, the pancreatic cancer microenvironment is chara...
Combining Irreversible Electroporation with Immunotherapy for the Systemic Treatment of Pancreatic Cancer
Abstract The goal of cancer immunotherapy is to utilize the patient’s immune system to reject the invading “foreign” tumor. However, the pancreatic cancer microenvironment is chara...
Combining Irreversible Electroporation with Immunotherapy for the Systemic Treatment of Pancreatic Cancer
Abstract The goal of cancer immunotherapy is to utilize the patient’s immune system to reject the invading “foreign” tumor. However, the pancreatic cancer microenvironment is chara...
Class II artificial antigen presenting cells for cancer immunotherapy
Project Summary Adoptive cell therapy (ACT) has become an increasingly attractive method for treating patients with solid tumors due to its impressive response rate; that said, the...
Class II artificial antigen presenting cells for cancer immunotherapy
Project Summary Adoptive cell therapy (ACT) has become an increasingly attractive method for treating patients with solid tumors due to its impressive response rate; that said, the...
Lipid Metabolism-driven Drug Resistance in Multiple Myeloma
Abstract Multiple myeloma (MM) is characterized by the expansion of malignant plasma cells primarily in the bone marrow and has a 5-year survival rate of only 50%. Obesity increase...
Extracellular Vesicle-Based Digital Scoring Assay for Detecting Early-stage Hepatocellular Carcinoma
PROJECT SUMMARY Extracellular vesicles (EVs) are a heterogeneous group of phospholipid bilayer-enclosed particles that are released by all types of cells, and even more so by tumor...