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Showing 19,58119,600 of 20,252 grants

Completed NON-SBIR/STTR RPGS
Urine and serum biomarkers for early diagnosis and risk assessment of pancreatic cancer
NATIONAL CANCER INSTITUTE University of Pittsburgh At Pittsburgh United States 2021 – 2026

ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, primarily due to most cases being diagnosed at an advanced, incurable stage. While 5-year surviv...

$6.22M
USD
Completed TRAINING, INDIVIDUAL
The Role of Glucose-6-Phosphatase in Hepatocellular Carcinoma
NATIONAL CANCER INSTITUTE Ut Southwestern Medical Center United States 2021 – 2025

PROJECT SUMMARY Although hepatocellular carcinoma (HCC) is the most common form of liver cancer, there are few therapies that are effective in treating this malignant disease. With...

$474.5K
USD
Completed NON-SBIR/STTR RPGS
Advancing skin cancer prevention by tackling UV-induced clonogenic mutations
NATIONAL CANCER INSTITUTE Roswell Park Cancer Institute Corp United States 2021 – 2026

1 Squamous cell skin cancer (SCC) is the second most common cancer in the US. There are methods available 2 to prevent SCC but are not appropriately used because we lack methods of...

$5.93M
USD
Active NON-SBIR/STTR RPGS
De-implementation of Mammography Overuse in Older Racially and Ethnically Diverse Women
NATIONAL CANCER INSTITUTE Columbia University Health Sciences United States 2021 – 2026

PROJECT SUMMARY De-implementation is recognized as a critical but understudied area within implementation science (IS). Research is needed to determine the optimal methods and appr...

$5.08M
USD
Completed NON-SBIR/STTR RPGS
Determinants of Palliative Care Effectiveness for Patients with Metastatic Cancer
NATIONAL CANCER INSTITUTE Columbia University Health Sciences United States 2021 – 2026

Project Summary Palliative care is an interdisciplinary model of care with the overarching goal of improving quality of life for patients with serious illness through symptom manag...

$6.02M
USD
Completed TRAINING, INDIVIDUAL
The Role of Glucose-6-Phosphatase in Hepatocellular Carcinoma
NATIONAL CANCER INSTITUTE Ut Southwestern Medical Center United States 2021 – 2024

PROJECT SUMMARY Although hepatocellular carcinoma (HCC) is the most common form of liver cancer, there are few therapies that are effective in treating this malignant disease. With...

$164.4K
USD
Completed NON-SBIR/STTR RPGS
Urine and serum biomarkers for early diagnosis and risk assessment of pancreatic cancer
NATIONAL CANCER INSTITUTE University of Pittsburgh At Pittsburgh United States 2021 – 2026

ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, primarily due to most cases being diagnosed at an advanced, incurable stage. While 5-year surviv...

$5.85M
USD
Completed NON-SBIR/STTR RPGS
Determinants of Palliative Care Effectiveness for Patients with Metastatic Cancer
NATIONAL CANCER INSTITUTE Columbia University Health Sciences United States 2021 – 2026

Project Summary Palliative care is an interdisciplinary model of care with the overarching goal of improving quality of life for patients with serious illness through symptom manag...

$4.48M
USD
Completed NON-SBIR/STTR RPGS
Advancing skin cancer prevention by tackling UV-induced clonogenic mutations
NATIONAL CANCER INSTITUTE Roswell Park Cancer Institute Corp United States 2021 – 2026

1 Squamous cell skin cancer (SCC) is the second most common cancer in the US. There are methods available 2 to prevent SCC but are not appropriately used because we lack methods of...

$5.68M
USD
Active NON-SBIR/STTR RPGS
De-implementation of Mammography Overuse in Older Racially and Ethnically Diverse Women
NATIONAL CANCER INSTITUTE Columbia University Health Sciences United States 2021 – 2026

PROJECT SUMMARY De-implementation is recognized as a critical but understudied area within implementation science (IS). Research is needed to determine the optimal methods and appr...

$4.82M
USD
Completed NON-SBIR/STTR RPGS
The interplay of ion transporters and cytoskeleton in breast cancer migration and metastasis
NATIONAL CANCER INSTITUTE Johns Hopkins University United States 2021 – 2026

The inability to clinically treat tumor metastasis is responsible for the majority of cancer patient deaths.Cell migration is a pivotal step in the metastatic dissemination of canc...

$5.34M
USD
Completed NON-SBIR/STTR RPGS
The interplay of ion transporters and cytoskeleton in breast cancer migration and metastasis
NATIONAL CANCER INSTITUTE Johns Hopkins University United States 2021 – 2026

The inability to clinically treat tumor metastasis is responsible for the majority of cancer patient deaths. Cell migration is a pivotal step in the metastatic dissemination of can...

$4.87M
USD
Completed NON-SBIR/STTR RPGS
The interplay of ion transporters and cytoskeleton in breast cancer migration and metastasis
NATIONAL CANCER INSTITUTE Johns Hopkins University United States 2021 – 2026

The inability to clinically treat tumor metastasis is responsible for the majority of cancer patient deaths. Cell migration is a pivotal step in the metastatic dissemination of can...

$776.4K
USD
Completed NON-SBIR/STTR RPGS
The interplay of ion transporters and cytoskeleton in breast cancer migration and metastasis
NATIONAL CANCER INSTITUTE Johns Hopkins University United States 2021 – 2026

The inability to clinically treat tumor metastasis is responsible for the majority of cancer patient deaths. Cell migration is a pivotal step in the metastatic dissemination of can...

$4.82M
USD
Completed NON-SBIR/STTR RPGS
The interplay of ion transporters and cytoskeleton in breast cancer migration and metastasis
NATIONAL CANCER INSTITUTE Johns Hopkins University United States 2021 – 2026

The inability to clinically treat tumor metastasis is responsible for the majority of cancer patient deaths. Cell migration is a pivotal step in the metastatic dissemination of can...

$776.4K
USD
Completed NON-SBIR/STTR RPGS
The interplay of ion transporters and cytoskeleton in breast cancer migration and metastasis
NATIONAL CANCER INSTITUTE Johns Hopkins University United States 2021 – 2026

The inability to clinically treat tumor metastasis is responsible for the majority of cancer patient deaths. Cell migration is a pivotal step in the metastatic dissemination of can...

$4.62M
USD
Completed NON-SBIR/STTR RPGS
The interplay of ion transporters and cytoskeleton in breast cancer migration and metastasis
NATIONAL CANCER INSTITUTE Johns Hopkins University United States 2021 – 2026

The inability to clinically treat tumor metastasis is responsible for the majority of cancer patient deaths. Cell migration is a pivotal step in the metastatic dissemination of can...

$272.2K
USD
Completed NON-SBIR/STTR RPGS
Peer Coaching for Physical Activity Promotion among Breast Cancer Survivors: Adapting an Efficacious Intervention to Prepare for Implementation
NATIONAL CANCER INSTITUTE University of South Carolina At Columbia United States 2021 – 2025

Interventions promoting physical activity among cancer survivors improve their functioning, reduce fatigue and offer other benefits in cancer recovery and risk reduction for future...

$3.6M
USD
Completed TRAINING, INSTITUTIONAL
Integrated Training in Quantitative and Experimental Cancer Systems Biology
NATIONAL CANCER INSTITUTE Oregon Health & Science University United States 2021 – 2026

Project Summary There is an outstanding need for a national cadre of quantitatively sophisticated oncologists, with deep training in both biological aspects of cancer and computati...

$2.42M
USD
Completed NON-SBIR/STTR RPGS
Understanding affective processing of scientific evidence to promote informed choice for breast cancer screening
NATIONAL CANCER INSTITUTE University of Colorado Denver United States 2021 – 2026

Project Summary/Abstract Cancer screening for the right patients at the right level of cancer risk can save lives, but over the last several years many expert groups have de-intens...

$6.64M
USD