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20,252 grants found
Showing 19,001 – 19,020 of 20,252 grants
Comprehensive analyses of HOXB13-regulated transcriptional programs critical for prostate cancer progression
Summary Prostate cancer (PCa) is the most commonly diagnosed non-skin cancer in American men. Early-stage PCa can be effectively ablated with surgery and/or radiation treatments. H...
Circulating Genomic Determinants of Treatment Failure in Hodgkin Lymphoma
PROJECT SUMMARY/ABSTRACT PIs: Ash Alizadeh, M.D./Ph.D. & Maximilian Diehn, M.D./Ph.D. Classical Hodgkin lymphoma (HL) is among the most curable human malignancies.However, stra...
Improving our understanding of breast cancer mortality disparities through recurrence: a multi-level approach among women in Georgia
PROJECT SUMMARY/ABSTRACT Significance.Although national and philanthropic efforts have sought to reduce and eliminate breast cancer (BC) mortality disparities over the past few dec...
Targeting Oncostatin M-Receptor to Suppress Metastasis and Therapy Failure
ABSTRACT The metastatic spread of cancer cells and recurrence are intimately linked to therapy failure, which remains an important clinical challenge for patients with metastatic T...
Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer
Project Summary Triple-negative breast cancer (TNBC) has the highest patient death rate of all breast cancer subtypes.Several molecular targets have been identified for breast canc...
Targeting Oncostatin M-Receptor to Suppress Metastasis and Therapy Failure
ABSTRACT The metastatic spread of cancer cells and recurrence are intimately linked to therapy failure, which remains an important clinical challenge for patients with metastatic T...
Circulating Genomic Determinants of Treatment Failure in Hodgkin Lymphoma
PROJECT SUMMARY/ABSTRACT PIs: Ash Alizadeh, M.D./Ph.D. & Maximilian Diehn, M.D./Ph.D. Classical Hodgkin lymphoma (HL) is among the most curable human malignancies. However, str...
Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer
Project Summary Triple-negative breast cancer (TNBC) has the highest patient death rate of all breast cancer subtypes. Several molecular targets have been identified for breast can...
Improving our understanding of breast cancer mortality disparities through recurrence: a multi-level approach among women in Georgia
PROJECT SUMMARY/ABSTRACT Significance. Although national and philanthropic efforts have sought to reduce and eliminate breast cancer (BC) mortality disparities over the past few de...
Improving our understanding of breast cancer mortality disparities through recurrence: a multi-level approach among women in Georgia
PROJECT SUMMARY/ABSTRACT Significance. Although national and philanthropic efforts have sought to reduce and eliminate breast cancer (BC) mortality disparities over the past few de...
Targeting Oncostatin M-Receptor to Suppress Metastasis and Therapy Failure
ABSTRACT The metastatic spread of cancer cells and recurrence are intimately linked to therapy failure, which remains an important clinical challenge for patients with metastatic T...
Improving our understanding of breast cancer mortality disparities through recurrence: a multi-level approach among women in Georgia
PROJECT SUMMARY/ABSTRACT Significance. Although national and philanthropic efforts have sought to reduce and eliminate breast cancer (BC) mortality disparities over the past few de...
Circulating Genomic Determinants of Treatment Failure in Hodgkin Lymphoma
PROJECT SUMMARY/ABSTRACT PIs: Ash Alizadeh, M.D./Ph.D. & Maximilian Diehn, M.D./Ph.D. Classical Hodgkin lymphoma (HL) is among the most curable human malignancies. However, str...
Comprehensive analyses of HOXB13-regulated transcriptional programs critical for prostate cancer progression
Summary Prostate cancer (PCa) is the most commonly diagnosed non-skin cancer in American men. Early-stage PCa can be effectively ablated with surgery and/or radiation treatments. H...
Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer
Project Summary Triple-negative breast cancer (TNBC) has the highest patient death rate of all breast cancer subtypes. Several molecular targets have been identified for breast can...
Improving our understanding of breast cancer mortality disparities through recurrence: a multi-level approach among women in Georgia
PROJECT SUMMARY/ABSTRACT Significance. Although national and philanthropic efforts have sought to reduce and eliminate breast cancer (BC) mortality disparities over the past few de...
Targeting Oncostatin M-Receptor to Suppress Metastasis and Therapy Failure
ABSTRACT The metastatic spread of cancer cells and recurrence are intimately linked to therapy failure, which remains an important clinical challenge for patients with metastatic T...
Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer
Project Summary Triple-negative breast cancer (TNBC) has the highest patient death rate of all breast cancer subtypes. Several molecular targets have been identified for breast can...
Circulating Genomic Determinants of Treatment Failure in Hodgkin Lymphoma
PROJECT SUMMARY/ABSTRACT PIs: Ash Alizadeh, M.D./Ph.D. & Maximilian Diehn, M.D./Ph.D. Classical Hodgkin lymphoma (HL) is among the most curable human malignancies. However, str...
Single cell quantification of genomic instability in cancer as a determinant of therapeutic response
PROJECT ABSTRACT Tumor genetic heterogeneity is an extensive feature of cancer biology and underlies patient response to therapy.One aspect of tumor heterogeneity that has been dif...