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20,252 grants found
Showing 18,981 – 19,000 of 20,252 grants
Harnessing the EHR for the Delivery of Supportive Care in an Oncology Setting
Project Summary Symptom management and supportive care are essential to high-quality cancer care and optimal patient outcomes, but many barriers exist to their integration in routi...
Therapeutic implication of RB1 loss in bladder cancer
Abstract This proposal describes a 5-year research career development program focused on a non-canonical role of RB1 loss in bladder cancer. Dr. Qiang Li is an Assistant Professor...
An integrated polymeric carrier for subunit cancer vaccines
PROJECT SUMMARY Cancer vaccines are a promising immuno-oncology approach that can elicit highly tumor-specific responses from the immune system, resulting in prolonged anti-cancer...
An integrated polymeric carrier for subunit cancer vaccines
PROJECT SUMMARY Cancer vaccines are a promising immuno-oncology approach that can elicit highly tumor-specific responses from the immune system, resulting in prolonged anti-cancer...
Adipokine Signaling as a Therapeutically Targetable Driver of Tumor Metabolism
Project Summary: The link between obesity and cancer is well-established epidemiologically, but poorly understood at a mechanistic level. Clear cell renal cell carcinoma (ccRCC) is...
Therapeutic implication of RB1 loss in bladder cancer
Abstract This proposal describes a 5-year research career development program focused on a non-canonical role of RB1 loss in bladder cancer. Dr. Qiang Li is an Assistant Professor...
Targeting tumor-neural cell interactions to inhibit lung cancer brain metastasis
Brain metastases account for decreased survival, increased morbidity, impaired cognition and poor quality of life for patients with lung cancer. Effective therapies for the treatme...
Understanding and improving responses to adaptive NK cell therapy for leukemia and multiple myeloma
Project Summary Natural killer (NK) cells are potent, effector lymphocytes with the ability to kill malignant and virally infected cells by releasing lytic granules without the nee...
Therapeutic implication of RB1 loss in bladder cancer
Abstract This proposal describes a 5-year research career development program focused on a non-canonical role of RB1 loss in bladder cancer. Dr. Qiang Li is an Assistant Professor...
Understanding and improving responses to adaptive NK cell therapy for leukemia and multiple myeloma
Project Summary Natural killer (NK) cells are potent, effector lymphocytes with the ability to kill malignant and virally infected cells by releasing lytic granules without the nee...
Therapeutic implication of RB1 loss in bladder cancer
Abstract This proposal describes a 5-year research career development program focused on a non-canonical role of RB1 loss in bladder cancer. Dr.Qiang Li is an Assistant Professor o...
Harnessing the EHR for the Delivery of Supportive Care in an Oncology Setting
Project Summary Symptom management and supportive care are essential to high-quality cancer care and optimal patient outcomes, but many barriers exist to their integration in routi...
Adipokine Signaling as a Therapeutically Targetable Driver of Tumor Metabolism
Project Summary: The link between obesity and cancer is well-established epidemiologically, but poorly understood at a mechanistic level.Clear cell renal cell carcinoma (ccRCC) is...
Understanding and improving responses to adaptive NK cell therapy for leukemia and multiple myeloma
Project Summary Natural killer (NK) cells are potent, effector lymphocytes with the ability to kill malignant and virally infected cells by releasing lytic granules without the nee...
An integrated polymeric carrier for subunit cancer vaccines
PROJECT SUMMARY Cancer vaccines are a promising immuno-oncology approach that can elicit highly tumor-specific responses from the immune system, resulting in prolonged anti-cancer...
Harnessing the EHR for the Delivery of Supportive Care in an Oncology Setting
Project Summary Symptom management and supportive care are essential to high-quality cancer care and optimal patient outcomes, but many barriers exist to their integration in routi...
Targeting tumor-neural cell interactions to inhibit lung cancer brain metastasis
Brain metastases account for decreased survival, increased morbidity, impaired cognition and poor quality of life for patients with lung cancer.Effective therapies for the treatmen...
Targeting tumor-neural cell interactions to inhibit lung cancer brain metastasis
Brain metastases account for decreased survival, increased morbidity, impaired cognition and poor quality of life for patients with lung cancer. Effective therapies for the treatme...
Adipokine Signaling as a Therapeutically Targetable Driver of Tumor Metabolism
Project Summary: The link between obesity and cancer is well-established epidemiologically, but poorly understood at a mechanistic level. Clear cell renal cell carcinoma (ccRCC) is...
Mechanisms of Lysosome Mediated Immune Evasion in Pancreatic Cancer
Project Summary/Abstract Pancreatic ductal adenocarcinoma (PDA), a malignancy refractory to most therapies including immune checkpoint blockade (ICB) therapy, utilizes diverse mech...