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Showing 18,12118,140 of 20,252 grants

Completed NON SBIR/STTR CONTRACTS
NCI PATTERNS OF CARE (POC)/QUALITY OF CARE STUDY: DIAGNOSIS YEAR 2019 (URINARY BLADDER CANCER AND KIDNEY CANCER)
NATIONAL CANCER INSTITUTE University of Kentucky United States 2021 – 2022

The primary objectives of the Fiscal Year 2021 NCI POC Study are to: 1) describe the use of recommended biomarker tests which shall be verified with the treating physician/physicia...

$2.11M
USD
Completed NON SBIR/STTR CONTRACTS
NCI PATTERNS OF CARE (POC)/QUALITY OF CARE STUDY: DIAGNOSIS YEAR 2019 (URINARY BLADDER CANCER AND KIDNEY CANCER)
NATIONAL CANCER INSTITUTE University of California, San Francisco United States 2021 – 2022

The primary objectives of the Fiscal Year 2021 NCI POC Study are to: 1) describe the use of recommended biomarker tests which shall be verified with the treating physician/physicia...

$1.78M
USD
Completed NON SBIR/STTR CONTRACTS
NCI PATTERNS OF CARE (POC)/QUALITY OF CARE STUDY: DIAGNOSIS YEAR 2019 (URINARY BLADDER CANCER AND KIDNEY CANCER)
NATIONAL CANCER INSTITUTE Emory University United States 2021 – 2022

The primary objectives of the Fiscal Year 2021 NCI POC Study are to: 1) describe the use of recommended biomarker tests which shall be verified with the treating physician/physicia...

$1.38M
USD
Completed NON SBIR/STTR CONTRACTS
NCI PATTERNS OF CARE (POC)/QUALITY OF CARE STUDY: DIAGNOSIS YEAR 2019 (URINARY BLADDER CANCER AND KIDNEY CANCER)
NATIONAL CANCER INSTITUTE Lsu Health Sciences Center United States 2021 – 2022

The primary objectives of the Fiscal Year 2021 NCI POC Study are to: 1) describe the use of recommended biomarker tests which shall be verified with the treating physician/physicia...

$807.1K
USD
Completed NON SBIR/STTR CONTRACTS
NCI PATTERNS OF CARE (POC)/QUALITY OF CARE STUDY: DIAGNOSIS YEAR 2019 (URINARY BLADDER CANCER AND KIDNEY CANCER)
NATIONAL CANCER INSTITUTE University of New Mexico Health Scis Ctr United States 2021 – 2022

The primary objectives of the Fiscal Year 2021 NCI POC Study are to: 1) describe the use of recommended biomarker tests which shall be verified with the treating physician/physicia...

$731.4K
USD
Completed NON SBIR/STTR CONTRACTS
NCI PATTERNS OF CARE (POC)/QUALITY OF CARE STUDY: DIAGNOSIS YEAR 2019 (URINARY BLADDER CANCER AND KIDNEY CANCER)
NATIONAL CANCER INSTITUTE University of Hawaii At Manoa United States 2021 – 2022

The primary objectives of the Fiscal Year 2021 NCI POC Study are to: 1) describe the use of recommended biomarker tests which shall be verified with the treating physician/physicia...

$561K
USD
Completed NON SBIR/STTR CONTRACTS
NCI PATTERNS OF CARE (POC)/QUALITY OF CARE STUDY: DIAGNOSIS YEAR 2019 (URINARY BLADDER CANCER AND KIDNEY CANCER)
NATIONAL CANCER INSTITUTE University of Iowa United States 2021 – 2022

The primary objectives of the Fiscal Year 2021 NCI POC Study are to: 1) describe the use of recommended biomarker tests which shall be verified with the treating physician/physicia...

$856K
USD
Completed NON-SBIR/STTR RPGS
Implications of metabolic heterogeneity on collective lung cancer cell invasion
NATIONAL CANCER INSTITUTE Emory University United States 2021 – 2026

Project Summary Most studies investigate whole cancer cell populations and rarely address how single cells or sub-populations cooperate to promote their survival and spread. This i...

$4.41M
USD
Completed NON-SBIR/STTR RPGS
Deciphering heritability, plasticity and differentiation trajectories in gliomas via single-cell multi-omics
NATIONAL CANCER INSTITUTE Massachusetts General Hospital United States 2021 – 2026

Abstract Cancer evolution constitutes a foremost obstacle to effective treatment, driving malignant cells to adapt and overcome therapy. Diffuse glioma illustrates the quandary of...

$5.3M
USD
Completed NON-SBIR/STTR RPGS
Implications of metabolic heterogeneity on collective lung cancer cell invasion
NATIONAL CANCER INSTITUTE Emory University United States 2021 – 2026

Project Summary Most studies investigate whole cancer cell populations and rarely address how single cells or sub-populations cooperate to promote their survival and spread. This i...

$4.19M
USD
Completed NON-SBIR/STTR RPGS
Effects of inflammaging on intestinal epithelial cells and aspirin chemoprevention.
NATIONAL CANCER INSTITUTE Massachusetts General Hospital United States 2021 – 2026

PROJECT ABSTRACT Previous randomized controlled trials (RCT)s demonstrate that low-dose aspirin (LDA, 81-100mg/day) reduces the risk of colorectal cancer (CRC). The U.S. Preventive...

$8.75M
USD
Completed NON SBIR/STTR CONTRACTS
NCI PATTERNS OF CARE (POC)/QUALITY OF CARE STUDY: DIAGNOSIS YEAR 2019 (URINARY BLADDER CANCER AND KIDNEY CANCER)
NATIONAL CANCER INSTITUTE University of Utah United States 2021 – 2022

The primary objectives of the Fiscal Year 2021 NCI POC Study are to: 1) describe the use of recommended biomarker tests which shall be verified with the treating physician/physicia...

$593.3K
USD
Completed NON SBIR/STTR CONTRACTS
NCI PATTERNS OF CARE (POC)/QUALITY OF CARE STUDY: DIAGNOSIS YEAR 2019 (URINARY BLADDER CANCER AND KIDNEY CANCER)
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Research Center United States 2021 – 2022

The primary objectives of the Fiscal Year 2021 NCI POC Study are to: 1) describe the use of recommended biomarker tests which shall be verified with the treating physician/physicia...

$959.9K
USD
Completed NON-SBIR/STTR RPGS
High-efficiency microfluidic cell fusion for dendritic cell/tumor cell vaccine production
NATIONAL CANCER INSTITUTE Massachusetts Institute of Technology United States 2021 – 2024

Project Summary Personalized immunotherapy using cancer vaccines made of dendritic-tumor (DC/Tumor) hybrid cells is being developed for a range of cancers, starting with acute myel...

$4.29M
USD
Completed NON-SBIR/STTR RPGS
Photonics probing of DNA mass density spatial structure for cancer diagnostics
NATIONAL CANCER INSTITUTE Mississippi State University United States 2021 – 2024

Abstract Cancer is known to be associated with genetic mutations. Evidences suggest that these genetic changes lead to increased structural disorder in biological cell nuclei. This...

$3.97M
USD
Completed NON-SBIR/STTR RPGS
Identifying neuroblastoma drivers and bringing them to the clinic
NATIONAL CANCER INSTITUTE Ut Southwestern Medical Center United States 2021 – 2024

Project Summary Our overall goal is to improve outcomes for children with forms of cancer that cannot be eradicated with current therapies.We are focused on neuroblastoma, an espec...

$4.37M
USD
Completed NON-SBIR/STTR RPGS
Characterization and targeting the CXCR2-STAT-1/3 axis in metastatic Ewing sarcoma
NATIONAL CANCER INSTITUTE Baylor College of Medicine United States 2021 – 2024

Project Summary Ewing Sarcoma (EwS) is the second most common bone tumor in children. At diagnosis, approximately 25-30% of patients with EwS have metastatic disease.For localized...

$4.13M
USD
Completed NON-SBIR/STTR RPGS
Novel Radiomics for Predicting Response to Immunotherapy for Lung Cancer
NATIONAL CANCER INSTITUTE Case Western Reserve University United States 2021 – 2022

ABSTRACT: In 2019, an estimated 228,150 patients in the US are expected to be diagnosed with non-small cell lung cancer (NSCLC).A recent landmark development has been the approval...

$6.2M
USD
Completed NON-SBIR/STTR RPGS
Novel Radiomics for Predicting Response to Immunotherapy for Lung Cancer
NATIONAL CANCER INSTITUTE Emory University United States 2021 – 2026

ABSTRACT: In 2019, an estimated 228,150 patients in the US are expected to be diagnosed with non-small cell lung cancer (NSCLC). A recent landmark development has been the approval...

$5.67M
USD
Completed NON-SBIR/STTR RPGS
Improving response to immunotherapy by genistein and antiestrogens
NATIONAL CANCER INSTITUTE University of Minnesota United States 2021 – 2023

Cancer immunotherapies have been remarkably successful in treating many previously incurable cancers. However, their utility in advanced breast cancer has been limited.For example,...

$4.08M
USD