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20,252 grants found
Showing 17,961 – 17,980 of 20,252 grants
DEVELOPMENT & MANUFACTURE OF ORAL & TOPICAL DOSAGE FORMS - NOVOBIOCIN CAPSULE PRODUCTION BASE (TASK 1) 12 MONTHS & OPTION 1 (TASK 2) A CGMP BATCH SHEL
The aim of the contract to manufacture Drug Product (Novobiocin is Capsule and Triapine is Injectable)
Mechanisms Of Akt Regulation
Abstract: The Ser/Thr protein kinase Akt1 is key signaling enzyme that participates in the regulation of cell growth and other physiologic processes, and its dysregulation contribu...
Mechanisms Of Akt Regulation
Abstract: The Ser/Thr protein kinase Akt1 is key signaling enzyme that participates in the regulation of cell growth and other physiologic processes, and its dysregulation contribu...
Biomaterial Scaffolds for Ex Vivo and In Situ CAR-T Cell Production
PROJECT SUMMARY Despite unprecedented clinical success of chimeric antigen receptor (CAR)-T cell therapy against tumors, widespread application is limited by lengthy and labor-inte...
Radiation-induced senescence in the brain microenvironment: Implications for glioblastoma recurrence and therapy
Abstract Glioblastomas (GBM) are aggressive and radioresistant brain cancers for which better therapeutic approaches are desperately needed.GBM patients are treated with 50-60 Gy o...
Contributions of SETD2 mutations in clear cell renal cell carcinoma (ccRCC)
Project Summary Cancer epigenetics has driven a surge of research in recent years as several chromatin- associated factors have been identified in the process of tumorigenesis.A cr...
Administrative Supplement for the Evaluation of the novel, uni-directional, Pd-103 CivaSheet for Lung Cancer
Parent Award: R44CA217587 Clinical Evaluation of the novel, Uni-directional Pd-103 CivaSheet for Lung Cancers CivaTech Oncology?s mission is to provide improved radiation therapy d...
TITLE: PHARMACOKINETIC AND ORAL BIOAVAILABILITY STUDIES IN RATS.PERIOD OF PERFORMANCE: 4/16/2021 TO 4/15/2022SEVERABLE - FIXED PRICE TYPE TASK ORDER
This Task Order was awarded under an IDIQ contract pool which provides a resource for conducting nonclinical pharmacology, pharmacokinetic, and metabolism studies with candidate th...
Radiation-induced senescence in the brain microenvironment: Implications for glioblastoma recurrence and therapy
Abstract Glioblastomas (GBM) are aggressive and radioresistant brain cancers for which better therapeutic approaches are desperately needed. GBM patients are treated with 50-60 Gy...
Biomaterial Scaffolds for Ex Vivo and In Situ CAR-T Cell Production
PROJECT SUMMARY Despite unprecedented clinical success of chimeric antigen receptor (CAR)-T cell therapy against tumors, widespread application is limited by lengthy and labor-inte...
Contributions of SETD2 mutations in clear cell renal cell carcinoma (ccRCC)
Project Summary Cancer epigenetics has driven a surge of research in recent years as several chromatin- associated factors have been identified in the process of tumorigenesis. A c...
TITLE: PHARMACOKINETIC AND ORAL BIOAVAILABILITY STUDIES IN RATS.PERIOD OF PERFORMANCE: 4/16/2021 TO 4/15/2022SEVERABLE - FIXED PRICE TYPE TASK ORDER
This Task Order was awarded under an IDIQ contract pool which provides a resource for conducting nonclinical pharmacology, pharmacokinetic, and metabolism studies with candidate th...
Radiation-induced senescence in the brain microenvironment: Implications for glioblastoma recurrence and therapy
Abstract Glioblastomas (GBM) are aggressive and radioresistant brain cancers for which better therapeutic approaches are desperately needed. GBM patients are treated with 50-60 Gy...
Biomaterial Scaffolds for Ex Vivo and In Situ CAR-T Cell Production
PROJECT SUMMARY Despite unprecedented clinical success of chimeric antigen receptor (CAR)-T cell therapy against tumors, widespread application is limited by lengthy and labor-inte...
Contributions of SETD2 mutations in clear cell renal cell carcinoma (ccRCC)
Project Summary Cancer epigenetics has driven a surge of research in recent years as several chromatin- associated factors have been identified in the process of tumorigenesis. A c...
Biomaterial Scaffolds for Ex Vivo and In Situ CAR-T Cell Production
PROJECT SUMMARY Despite unprecedented clinical success of chimeric antigen receptor (CAR)-T cell therapy against tumors, widespread application is limited by lengthy and labor-inte...
Radiation-induced senescence in the brain microenvironment: Implications for glioblastoma recurrence and therapy
Abstract Glioblastomas (GBM) are aggressive and radioresistant brain cancers for which better therapeutic approaches are desperately needed. GBM patients are treated with 50-60 Gy...
Contributions of SETD2 mutations in clear cell renal cell carcinoma (ccRCC)
Project Summary Cancer epigenetics has driven a surge of research in recent years as several chromatin- associated factors have been identified in the process of tumorigenesis. A c...
Biomaterial Scaffolds for Ex Vivo and In Situ CAR-T Cell Production
PROJECT SUMMARY Despite unprecedented clinical success of chimeric antigen receptor (CAR)-T cell therapy against tumors, widespread application is limited by lengthy and labor-inte...
Using Natural Language Processing and Crowdsourcing to Monitor and Evaluate Public Information and Communication Disparities about Colon Cancer Screening
PROJECT SUMMARY Colorectal cancer (CRC) incidence and death rates are higher among Black Americans than non-Hispanic White Americans. While some CRC-related disparities have decrea...