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20,252 grants found
Showing 17,761 – 17,780 of 20,252 grants
The Role of Rac1 in Ovarian Cancer Metastasis and Niche Interaction
PROJECT ABSTRACT Ovarian cancer patients continue to have a high mortality rate due to late stage diagnoses and frequent relapse. Ovarian cancer is not exclusively confined to the...
Cancer Biology Program
The Virginia Commonwealth University (VCU) Massey Cancer Center (MCC) created the new Cancer Biology (CB) program in 2020 by merging the former Cancer Cell Signaling and Cancer Mol...
Defining the Biochemical Functions of the TSC Tumor Suppressors in mTORC1 Signaling
Project Summary/Abstract Many growth factor signaling pathways converge on the tuberous sclerosis complex (TSC) complex to activate the mechanistic target of rapamycin complex 1 (m...
Dissecting the roles of Runx3 and Mll1 in dysfunctional T cell responses to tumors
Project Summary/Abstract: CD8+ T cells differentiate into cytotoxic T lymphocytes (CTLs), to directly engage malignant cells and cause their lysis via exocytosis of cytotoxic granu...
Targeting the Stroma for Pancreatic Cancer Treatment
PROJECT SUMMARY Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest malignancies despite the recent paradigm shifting success of immunotherapy noted in many other...
Decoupling Bidirectional EphB/ephrinB2 in Multiple Myeloma
Project Summary/Abstract My research objectives are to study the impact of decoupling the EphB4/ephrinB2 axis in multiple myeloma (MM), a cancer of antibody-secreting plasma cells,...
SURVEILLANCE EPIDEMIOLOGY AND END RESULTS (SEER) PROGRAM - TASK AREA 1 - PROGRAMMATIC MEETING
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
SURVEILLANCE EPIDEMIOLOGY AND END RESULTS (SEER) PROGRAM - TASK AREA 1 - PROGRAMMATIC MEETING
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
SURVEILLANCE EPIDEMIOLOGY AND END RESULTS (SEER) PROGRAM - TASK AREA 1 - PROGRAMMATIC MEETING
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
THE PURPOSE OF THIS MODIFICATION IS TO PROVIDE A NO-COST EXTENSION TO EXTEND THE PERIOD OF PERFORMANCE.
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
THE PURPOSE OF THIS MODIFICATION IS TO PROVIDE A NO-COST EXTENSION TO THE PERIOD OF PERFORMANCE.
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
Programmatic Meeting for Surveillance, Epidemiology and End Results (SEER)
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
Mod No. P00001-Task Order Task Area 1 - ProgrammaticMeeting for Surveillance, Epidemiology and End Results (Research Support Only)
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
SEER CORE INFRASTRUCTURE SUPPORT
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
Surveillance Epidemiology and End Results (SEER) Program - Task Area 1 - Programmatic Meeting
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
Biological determinants of colorectal cancer outcomes in Latinos of diverseýancestral origins
ABSTRACT Hispanics/Latinos (Latinos) are the 2nd largest and fastest growing ethnic group in the United States. Although typically grouped as a single ethnic minority, Latinos are...
The Nathan Schnaper Intern Program in Translational Cancer Research
Significant progress in detection and treatment has reduced cancer mortality rates; however, with over 1.7 million new cases and 600,000 deaths from cancer reported in 2019, it rem...
Exosomes in HNSCC Progression
Exosomes are small extracellular vesicles (EVs) that are secreted from multivesicular endosomes (MVE) and have been recently recognized to promote cancer metastasis. Exosomes carry...
Paper-based Breastmilk Collection System for Facile, In-Home Use
Project Summary / Abstract This project will conduct early-stage development of a paper-based device to facilitate the efficient recovery of high-quality nucleic acids from breastm...
Intratumoral Heterogeneity and Plasticity in Basal-Like Breast Cancers
Project Summary Triple Negative Breast Cancer (TNBC) is an aggressive malignancy with a poor prognosis that accounts for 10- 20% of breast cancer cases worldwide. Tumor resistance...