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Showing 17,56117,580 of 20,252 grants

Completed NON-SBIR/STTR RPGS
Investigating the mechanisms of driver genes associated with ancestry and aggressiveness in prostate cancer
NATIONAL CANCER INSTITUTE Boston University Medical Campus United States 2021 – 2026

Summary African American (AA) men have the highest incidence and mortality rate from prostate cancer in the United States.We recently showed that AA men with low-risk prostate canc...

$6.1M
USD
Completed NON-SBIR/STTR RPGS
RNASEH2B loss to predict response to PARP inhibitor in prostate cancer
NATIONAL CANCER INSTITUTE Brigham and Women'S Hospital United States 2021 – 2023

ABSTRACT Metastatic castration-resistant prostate cancer (CRPC) is an incurable disease that is expected to account for ~ 31,000 deaths each year in the United States. There are li...

$2.51M
USD
Completed NON-SBIR/STTR RPGS
Implementing Palliative Care: Learning Collaborative vs. Technical Assistance
NATIONAL CANCER INSTITUTE University of Alabama At Birmingham United States 2021 – 2024

Project Summary    The American Society of Clinical Oncology (ASCO) recommends ??combined standard oncology care and  palliative care?early in the course of illness for any patient...

$6.37M
USD
Completed NON-SBIR/STTR RPGS
Implementing Palliative Care: Learning Collaborative vs. Technical Assistance
NATIONAL CANCER INSTITUTE University of Alabama At Birmingham United States 2021 – 2024

Project Summary    The American Society of Clinical Oncology (ASCO) recommends “…combined standard oncology care and palliative care…early in the course of illness for any patient ...

$6.26M
USD
Completed NON-SBIR/STTR RPGS
Implementing Palliative Care: Learning Collaborative vs. Technical Assistance
NATIONAL CANCER INSTITUTE University of Alabama At Birmingham United States 2021 – 2026

Project Summary    The American Society of Clinical Oncology (ASCO) recommends “…combined standard oncology care and palliative care…early in the course of illness for any patient ...

$5.45M
USD
Completed NON-SBIR/STTR RPGS
Implementing Palliative Care: Learning Collaborative vs. Technical Assistance
NATIONAL CANCER INSTITUTE University of Alabama At Birmingham United States 2021 – 2025

Project Summary    The American Society of Clinical Oncology (ASCO) recommends “…combined standard oncology care and palliative care…early in the course of illness for any patient ...

$10
USD
Completed NON-SBIR/STTR RPGS
Exploiting Pyrimidine Nucleotide Synthesis Dependence for IDH Mutant Glioma Therapy
NATIONAL CANCER INSTITUTE Ut Southwestern Medical Center United States 2021 – 2026

PROJECT SUMMARY Gliomas represent 80% of the 26,000 newly diagnosed cases of malignant brain and central nervous system tumors in the United States each year and are among the most...

$3.75M
USD
Completed NON SBIR/STTR CONTRACTS
CENTRALIZED INSTITUTIONAL REVIEW BOARD TO REVIEW MINIMAL RISK REGISTRY LINKAGE STUDIES "CIRB
NATIONAL CANCER INSTITUTE Unknown United States 2021 – 2024

Over the past 15-years, unprecedented capacity and opportunity for large scale epidemiologic research has emerged, but a significant barrier still exists.Researchers who seek to ef...

$185.3K
USD
Completed NON SBIR/STTR CONTRACTS
DELIVERY OF CELL LINES/DERIVATIVES FOR RESEARCH PURPOSES
NATIONAL CANCER INSTITUTE American Type Culture Collection United States 2021 – 2022

The objective of this request is to procure up to an additional 150 cell lines and/or derivatives selected by OCG to be sent to collaborators and grantees as indicated by OCG. http...

$1.85M
USD
Completed NON-SBIR/STTR RPGS
Exploiting Pyrimidine Nucleotide Synthesis Dependence for IDH Mutant Glioma Therapy
NATIONAL CANCER INSTITUTE Ut Southwestern Medical Center United States 2021 – 2026

PROJECT SUMMARY Gliomas represent 80% of the 26,000 newly diagnosed cases of malignant brain and central nervous system tumors in the United States each year and are among the most...

$3.75M
USD
Completed NON SBIR/STTR CONTRACTS
CENTRALIZED INSTITUTIONAL REVIEW BOARD TO REVIEW MINIMAL RISK REGISTRY LINKAGE STUDIES "CIRB
NATIONAL CANCER INSTITUTE Unknown United States 2021 – 2023

Over the past 15-years, unprecedented capacity and opportunity for large scale epidemiologic research has emerged, but a significant barrier still exists. Researchers who seek to e...

$123.2K
USD
Completed NON-SBIR/STTR RPGS
Exploiting Pyrimidine Nucleotide Synthesis Dependence for IDH Mutant Glioma Therapy
NATIONAL CANCER INSTITUTE Ut Southwestern Medical Center United States 2021 – 2026

PROJECT SUMMARY Gliomas represent 80% of the 26,000 newly diagnosed cases of malignant brain and central nervous system tumors in the United States each year and are among the most...

$3.68M
USD
Completed NON SBIR/STTR CONTRACTS
CENTRALIZED INSTITUTIONAL REVIEW BOARD TO REVIEW MINIMAL RISK REGISTRY LINKAGE STUDIES "CIRB
NATIONAL CANCER INSTITUTE Unknown United States 2021 – 2023

Over the past 15-years, unprecedented capacity and opportunity for large scale epidemiologic research has emerged, but a significant barrier still exists. Researchers who seek to e...

$152.2K
USD
Completed NON-SBIR/STTR RPGS
Exploiting Pyrimidine Nucleotide Synthesis Dependence for IDH Mutant Glioma Therapy
NATIONAL CANCER INSTITUTE Ut Southwestern Medical Center United States 2021 – 2026

PROJECT SUMMARY Gliomas represent 80% of the 26,000 newly diagnosed cases of malignant brain and central nervous system tumors in the United States each year and are among the most...

$3.56M
USD
Completed NON-SBIR/STTR RPGS
Remote Monitoring of Management of Chemotherapy induced Peripheral Neuropathy
NATIONAL CANCER INSTITUTE University of Vermont & St Agric College United States 2021 – 2026

Chemotherapy induced peripheral neuropathy (CIPN) is a common and disabling side effect of chemotherapy. It frequently leads to chemotherapy dose alteration, pain, fall risk, and i...

$15.26M
USD
Active NON-SBIR/STTR RPGS
Remote Monitoring of Management of Chemotherapy induced Peripheral Neuropathy
NATIONAL CANCER INSTITUTE University of Vermont & St Agric College United States 2021 – 2027

Chemotherapy induced peripheral neuropathy (CIPN) is a common and disabling side effect of chemotherapy. It frequently leads to chemotherapy dose alteration, pain, fall risk, and i...

$5.01M
USD
Active NON-SBIR/STTR RPGS
Remote Monitoring of Management of Chemotherapy induced Peripheral Neuropathy
NATIONAL CANCER INSTITUTE University of Vermont & St Agric College United States 2021 – 2027

Chemotherapy induced peripheral neuropathy (CIPN) is a common and disabling side effect of chemotherapy. It frequently leads to chemotherapy dose alteration, pain, fall risk, and i...

$15.41M
USD
Completed NON-SBIR/STTR RPGS
Remote Monitoring of Management of Chemotherapy induced Peripheral Neuropathy
NATIONAL CANCER INSTITUTE University of Vermont & St Agric College United States 2021 – 2026

Chemotherapy induced peripheral neuropathy (CIPN) is a common and disabling side effect of chemotherapy. It frequently leads to chemotherapy dose alteration, pain, fall risk, and i...

$11.71M
USD
Completed OTHER RESEARCH-RELATED
BIDIRECTIONAL TRAINING TO ENHANCE CANCER RESEARCH CAPACITY IN AFRICA
NATIONAL CANCER INSTITUTE Dana-Farber Cancer Inst United States 2021 – 2026

PROJECT SUMMARY/ABSTRACT Cancer mortality rates are projected to more than double in Sub-Saharan Africa (SSA) in the next two decades. This public health crisis requires that a kno...

$2.7M
USD
Completed OTHER RESEARCH-RELATED
THE CANCER EPITOPE DATABASE AND ANALYSIS RESOURCE
NATIONAL CANCER INSTITUTE la Jolla Institute for Immunology United States 2021 – 2026

ABSTRACT Recent years have witnessed a dramatic rise in interest towards cancer epitopes in general, and neoepitopes that encompass mutations arising in a given tumor in particular...

$8.13M
USD