Browse All Grants
20,252 grants found
Showing 17,481 – 17,500 of 20,252 grants
Identifying modifiable factors that reduce the burden of late stage melanoma in Hispanics
Project Summary Hispanics are diagnosed with melanoma at later stages than their non-Hispanic white (NHW) counterparts, leading to increased likelihood of metastasis and worse surv...
Multi-strain, live biotherapeutics as adjuncts to checkpoint inhibitor therapy
PROJECT SUMMARY A series of recent studies have highlighted the importance of the composition of the gut microbiota as a factor determining the efficacy of checkpoint inhibitor the...
Multi-strain, live biotherapeutics as adjuncts to checkpoint inhibitor therapy
PROJECT SUMMARY A series of recent studies have highlighted the importance of the composition of the gut microbiota as a factor determining the efficacy of checkpoint inhibitor the...
Chemical Exchange Saturation Transfer (CEST) MRI for the Characterization Small Renal Masses
Project Summary An Academic-Industrial partnership between scientists and clinicians at the University of Texas Southwestern (UTSW) Medical Center and Philips Research Hamburg and...
Chemical Exchange Saturation Transfer (CEST) MRI for the Characterization Small Renal Masses
Project Summary An Academic-Industrial partnership between scientists and clinicians at the University of Texas Southwestern (UTSW) Medical Center and Philips Research Hamburg and...
Development of Programmable mRNA Circuits for Melanoma Immunotherapy
PROJECT SUMMARY While major strides have been made in the development of therapies for melanoma, cases continue to rise, with more diagnoses occurring at an early stage where surge...
Chemical Exchange Saturation Transfer (CEST) MRI for the Characterization Small Renal Masses
Project Summary An Academic-Industrial partnership between scientists and clinicians at the University of Texas Southwestern (UTSW) Medical Center and Philips Research Hamburg and...
Chemical Exchange Saturation Transfer (CEST) MRI for the Characterization Small Renal Masses
Project Summary An Academic-Industrial partnership between scientists and clinicians at the University of Texas Southwestern (UTSW) Medical Center and Philips Research Hamburg and...
Regulation of primary metastasis in high grade serous ovarian cancer
Project Summary/Abstract High grade serous ovarian cancer (HGSOC) is both the most common and most lethal ovarian cancer histotype. Though HGSOC has been long thought to originate...
Regulation of primary metastasis in high grade serous ovarian cancer
Project Summary/Abstract High grade serous ovarian cancer (HGSOC) is both the most common and most lethal ovarian cancer histotype. Though HGSOC has been long thought to originate...
Regulation of primary metastasis in high grade serous ovarian cancer
Project Summary/Abstract High grade serous ovarian cancer (HGSOC) is both the most common and most lethal ovarian cancer histotype. Though HGSOC has been long thought to originate...
Regulation of primary metastasis in high grade serous ovarian cancer
Project Summary/Abstract High grade serous ovarian cancer (HGSOC) is both the most common and most lethal ovarian cancer histotype.Though HGSOC has been long thought to originate i...
Tracking Adoptive T Cell Therapy Using Magnetic Particle Imaging
Project Summary Immunotherapy has tremendous promise for eradicating cancers.One approach to boost immune response to attack cancer is adoptive T cell transfer (ACT) using tumor-sp...
Positive Affect, Future Thinking, and Planning: Testing Brief Intervention Components to Optimize a Novel Intervention to Promote Physical Activity
Project Summary Insufficient levels of regular physical activity (< 150 minutes/week of moderate-to-vigorous physical activity [MVPA]) are associated with various health risks,...
Flow Responsive Embolic Agent for the Complete Devascularization of Meningiomas
PROJECT SUMMARY Significance: Pre-operative embolization (POE) of meningiomas is an established neuroendovascular procedure performed to reduce the extensive amount of blood loss t...
Image-guided Trp-IDO/TDO-Kyn-AHR pathway inhibition, combined with immunotherapy
ABSTRACT Despite recent progress in immunotherapy (checkpoint blockade and adoptive T cell transfer), most patients with solid tumors still do not respond or subsequently develop a...
Image-guided Trp-IDO/TDO-Kyn-AHR pathway inhibition, combined with immunotherapy
ABSTRACT Despite recent progress in immunotherapy (checkpoint blockade and adoptive T cell transfer), most patients with solid tumors still do not respond or subsequently develop a...
Image-guided Trp-IDO/TDO-Kyn-AHR pathway inhibition, combined with immunotherapy
ABSTRACT Despite recent progress in immunotherapy (checkpoint blockade and adoptive T cell transfer), most patients with solid tumors still do not respond or subsequently develop a...
Image-guided Trp-IDO/TDO-Kyn-AHR pathway inhibition, combined with immunotherapy
ABSTRACT Despite recent progress in immunotherapy (checkpoint blockade and adoptive T cell transfer), most patients with solid tumors still do not respond or subsequently develop a...
Engineering a potent locally-acting interleukin 12-expressing synthetic self-replicating mRNA to augment responses to anti-PD-1 therapy in neoadjuvant triple negative breast cancer
PROJECT SUMMARY Triple negative breast cancer (TNBC) has few treatments, and patients have a poor prognosis.Checkpoint inhibitors (e.g., anti-PD-1 antibodies) represent a promising...