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20,252 grants found
Showing 17,441 – 17,460 of 20,252 grants
High-throughput Label-free Biosensor Platform for Rapid Detection of Antigen-specific T Cells with Single Cell Resolution
Project Summary / Abstract Immunotherapy has become a rapidly growing segment of cancer treatment with impressive success across a spectrum of malignancies including melanoma, colo...
PRANAYAMA BASED GROUP VIDEO APP FOR CANCER SURVIVORSHIP. Phase I. Breast Cancer Pilot
PROJECT SUMMARY Cancer remains the second leading cause of deaths in the U.S.Encouragingly, recent improvements in early diagnosis and treatment has led to significant increases in...
The immunosuppressive function of secretory IgM in tumor-bearing mice
Project Summary/Abstract Myeloid-derived suppressor cells (MDSCs) exert potent immunosuppressive functions within tumor microenvironments to promote tumor growth.It is critical to...
Investigating the biology and therapeutic vulnerabilities of ER+ metastatic breast cancer with activating HER2 mutations
Project Summary/Abstract The candidate, Ms.Utthara Nayar, PhD, is a translational cancer biologist, and currently a Research Fellow in Medicine at Dana-Farber Cancer Institute, Har...
Quantitative Lung Function Imaging to Reduce Toxicity for patients treated with Radiation and Immunotherapy
The proposed project is in the field of thoracic oncology.Lung cancer patients that get treated with radiotherapy and immunotherapy are at risk of developing serious lung side-effe...
Targeted Chemical-Genetic Screen Platform for Identifying Novel AML Therapeutics
PROJECT ABSTRACT Over 93% of cancer patients do not receive therapeutic benefit from oncology precision medicine.This can be partly attributed to 1) not understanding the genetic t...
Development of a Novel Lung Function Imaging Modality for comprehensive management of lung cancer
Our project proposes an academic-industrial partnership to translate a novel lung function imaging modality into clinical care for lung cancer patients receiving radiation therapy....
Development of a Novel Lung Function Imaging Modality for comprehensive management of lung cancer
Our project proposes an academic-industrial partnership to translate a novel lung function imaging modality into clinical care for lung cancer patients receiving radiation therapy....
Development of a Novel Lung Function Imaging Modality for comprehensive management of lung cancer
Our project proposes an academic-industrial partnership to translate a novel lung function imaging modality into clinical care for lung cancer patients receiving radiation therapy....
Development of a Novel Lung Function Imaging Modality for comprehensive management of lung cancer
Our project proposes an academic-industrial partnership to translate a novel lung function imaging modality into clinical care for lung cancer patients receiving radiation therapy....
Development of a Novel Lung Function Imaging Modality for comprehensive management of lung cancer
Our project proposes an academic-industrial partnership to translate a novel lung function imaging modality into clinical care for lung cancer patients receiving radiation therapy....
Development of a Novel Lung Function Imaging Modality for comprehensive management of lung cancer
Our project proposes an academic-industrial partnership to translate a novel lung function imaging modality into clinical care for lung cancer patients receiving radiation therapy....
Development of a Novel Lung Function Imaging Modality for comprehensive management of lung cancer
Our project proposes an academic-industrial partnership to translate a novel lung function imaging modality into clinical care for lung cancer patients receiving radiation therapy....
Development of a Novel Lung Function Imaging Modality for comprehensive management of lung cancer
Our project proposes an academic-industrial partnership to translate a novel lung function imaging modality into clinical care for lung cancer patients receiving radiation therapy....
EpoxySEAKER and onSEAKER: CAR T-Cell Systems for Targeted Local Biosynthesis of Therapeutic Warheads
EPOXYSEAKER AND ONSEAKER: CAR T-CELL SYSTEMS FOR TARGETED LOCAL BIOSYNTHESIS OF THERAPEUTIC WARHEADS Our labs have developed novel SEAKER (Synthetic Enzyme-Armed KillER) CAR T-cell...
EpoxySEAKER and onSEAKER: CAR T-Cell Systems for Targeted Local Biosynthesis of Therapeutic Warheads
EPOXYSEAKER AND ONSEAKER: CAR T-CELL SYSTEMS FOR TARGETED LOCAL BIOSYNTHESIS OF THERAPEUTIC WARHEADS Our labs have developed novel SEAKER (Synthetic Enzyme-Armed KillER) CAR T-cell...
EpoxySEAKER and onSEAKER: CAR T-Cell Systems for Targeted Local Biosynthesis of Therapeutic Warheads
EPOXYSEAKER AND ONSEAKER: CAR T-CELL SYSTEMS FOR TARGETED LOCAL BIOSYNTHESIS OF THERAPEUTIC WARHEADS Our labs have developed novel SEAKER (Synthetic Enzyme-Armed KillER) CAR T-cell...
Identifying EZH2-dependent vulnerabilities in RB deficient prostate cancer
PROJECT SUMMARY Metastatic prostate cancer (mPCa) is incurable and responsible for the majority of PCa associated mortality.Therefore, there is a critical need to identify intercep...
Identifying EZH2-dependent vulnerabilities in RB deficient prostate cancer
PROJECT SUMMARY Metastatic prostate cancer (mPCa) is incurable and responsible for the majority of PCa associated mortality. Therefore, there is a critical need to identify interce...
PREVENT EFFICACY POOL: PREVENT CANCER PRECLINICAL DRUG DEVELOPMENT PROGRAM
Lung cancer is the leading cause of cancer mortality worldwide.KRAS is the most common oncogene in lung adenocarcinoma patients while EGFR mutations occur in 47.9% of Asia-Pacific...