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Showing 17,00117,020 of 20,252 grants

Completed NON-SBIR/STTR RPGS
Administrative Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

CORE 1 PROJECT SUMMARY ADMINISTRATIVE CORE The Administrative Core serves as the central node for all Projects and Cores of the Program Project Grant (PPG) with the overarching goa...

Completed NON-SBIR/STTR RPGS
Metabolomics Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

CORE 3 PROJECT SUMMARY METABOLISM CORE The Metabolism Core (Core #3) supports the metabolomics and proteomics experiments designed by program project grant (PPG) investigators as i...

Completed NON-SBIR/STTR RPGS
Data Science Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

CORE 4 PROJECT SUMMARY DATA SCIENCE CORE The mission of the Data Science Core (Core #4) is to serve as the focal point from which Program Project investigators can draw statistical...

Completed NON-SBIR/STTR RPGS
Project 1
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

PROJECT 1 SUMMARY IDENTIFYING METABOLIC VULNERABILITIES REGULATED BY THE P53 FAMILY IN LUNG CANCER p53 is commonly mutated in all subtypes of human lung cancer. p53 is part of a fa...

Completed NON-SBIR/STTR RPGS
Identifying Metabolic Vulnerabilities in Lung Cancer
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

OVERALL PROJECT SUMMARY IDENTIFYING METABOLIC VULNERABILITIES IN LUNG CANCER Lung Cancer is the most common cause of cancer deaths world-wide. Tyrosine kinase inhibitors and immuno...

$20.29M
USD
Completed NON-SBIR/STTR RPGS
Project 2
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

PROJECT 2 SUMMARY INVESTIGATING CYSTEINE ESSENTIALITY IN LUNG CANCER Cancer cells accumulate significant intracellular cysteine due to increased cystine uptake and loss of homeosta...

Completed NON-SBIR/STTR RPGS
Project 3
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

PROJECT 3 SUMMARY ROLES AND MECHANISMS OF ACTION OF METABOLIC VULNERABILITIES OF SCLC Small cell lung cancer (SCLC) lacks targeted therapies, and with only 7% overall survival on s...

Completed NON-SBIR/STTR RPGS
Project 4
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

PROJECT 4 SUMMARY: METABOLIC AND FUNCTIONAL REPROGRAMMING OF IMMUNOSUPPRESSIVE MYELOPOIESIS IN LUNG TUMORS Lung cancer cells and tumor-infiltrating immune subsets activate an integ...

Completed NON-SBIR/STTR RPGS
Administrative Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

CORE 1 PROJECT SUMMARY ADMINISTRATIVE CORE The Administrative Core serves as the central node for all Projects and Cores of the Program Project Grant (PPG) with the overarching goa...

Completed NON-SBIR/STTR RPGS
Pre-Clinical Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

CORE 2 PROJECT SUMMARY PRECLINICAL MODELS AND PATHOLOGY CORE The Preclinical Core (Core #2) leverages the knowledge and expertise from several Moffitt investigators and core facili...

Completed NON-SBIR/STTR RPGS
Metabolomics Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

CORE 3 PROJECT SUMMARY METABOLISM CORE The Metabolism Core (Core #3) supports the metabolomics and proteomics experiments designed by program project grant (PPG) investigators as i...

Completed NON-SBIR/STTR RPGS
Data Science Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

CORE 4 PROJECT SUMMARY DATA SCIENCE CORE The mission of the Data Science Core (Core #4) is to serve as the focal point from which Program Project investigators can draw statistical...

Completed NON-SBIR/STTR RPGS
Identifying Metabolic Vulnerabilities in Lung Cancer
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

OVERALL PROJECT SUMMARY IDENTIFYING METABOLIC VULNERABILITIES IN LUNG CANCER Lung Cancer is the most common cause of cancer deaths world-wide. Tyrosine kinase inhibitors and immuno...

$19.52M
USD
Completed NON-SBIR/STTR RPGS
Project 3
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

PROJECT 3 SUMMARY ROLES AND MECHANISMS OF ACTION OF METABOLIC VULNERABILITIES OF SCLC Small cell lung cancer (SCLC) lacks targeted therapies, and with only 7% overall survival on s...

Completed NON-SBIR/STTR RPGS
Project 4
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

PROJECT 4 SUMMARY: METABOLIC AND FUNCTIONAL REPROGRAMMING OF IMMUNOSUPPRESSIVE MYELOPOIESIS IN LUNG TUMORS Lung cancer cells and tumor-infiltrating immune subsets activate an integ...

Completed NON-SBIR/STTR RPGS
Administrative Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

CORE 1 PROJECT SUMMARY ADMINISTRATIVE CORE The Administrative Core serves as the central node for all Projects and Cores of the Program Project Grant (PPG) with the overarching goa...

Completed NON-SBIR/STTR RPGS
Pre-Clinical Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

CORE 2 PROJECT SUMMARY PRECLINICAL MODELS AND PATHOLOGY CORE The Preclinical Core (Core #2) leverages the knowledge and expertise from several Moffitt investigators and core facili...

Completed NON-SBIR/STTR RPGS
Project 4
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

PROJECT 4 SUMMARY: METABOLIC AND FUNCTIONAL REPROGRAMMING OF IMMUNOSUPPRESSIVE MYELOPOIESIS IN LUNG TUMORS Lung cancer cells and tumor-infiltrating immune subsets activate an integ...

Completed NON-SBIR/STTR RPGS
Administrative Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

CORE 1 PROJECT SUMMARY ADMINISTRATIVE CORE The Administrative Core serves as the central node for all Projects and Cores of the Program Project Grant (PPG) with the overarching goa...

Completed NON-SBIR/STTR RPGS
Pre-Clinical Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2021 – 2026

CORE 2 PROJECT SUMMARY PRECLINICAL MODELS AND PATHOLOGY CORE The Preclinical Core (Core #2) leverages the knowledge and expertise from several Moffitt investigators and core facili...