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20,252 grants found
Showing 16,981 – 17,000 of 20,252 grants
Project 3 – Stromal derived IL-6/STAT3 signaling in the development and progression of PDAC
PROJECT SUMMARY: PROJECT 3 PDAC is among the most deadly malignant solid tumors, with approximately 92% of patients succumbing to the disease within five years of diagnosis, and wi...
Core A - Administration
PROEJCT SUMMARY: CORE A The Administrative Core will provide centralized grant administration, data processing and administrative support for the projects. This Core will also serv...
Core B – Human Biospecimen and Advanced Sequencing Core
PROJECT SUMMARY: CORE B The goal of this Program is to advance knowledge of pancreatic ductal adenocarcinoma (PDAC), a recalcitrant cancer with one of the highest rates of cachexia...
Core C – Immunophenotyping Core
SUMMARY: CORE C Cachexia is a wasting syndrome that significantly contributes to the morbidity and mortality of cancer patients, especially those diagnosed with pancreatic ductal a...
Core D – Biostatistics Core
SUMMARY: CORE D The Biostatistics Core provides centralized and state-of-the-art support to meet the data management and analytic needs of the Program Project Grant. Core personnel...
Adapting and implementing evidence-based breast cancer follow-up in primary care
PROJECT SUMMARY/ABSTRACT Breast cancer survivors are a growing population and their symptom burden is significant. Despite growing evidence on specific symptoms and risk management...
Pre-Clinical Core
CORE 2 PROJECT SUMMARY PRECLINICAL MODELS AND PATHOLOGY CORE The Preclinical Core (Core #2) leverages the knowledge and expertise from several Moffitt investigators and core facili...
Metabolomics Core
CORE 3 PROJECT SUMMARY METABOLISM CORE The Metabolism Core (Core #3) supports the metabolomics and proteomics experiments designed by program project grant (PPG) investigators as i...
Data Science Core
CORE 4 PROJECT SUMMARY DATA SCIENCE CORE The mission of the Data Science Core (Core #4) is to serve as the focal point from which Program Project investigators can draw statistical...
Identifying Metabolic Vulnerabilities in Lung Cancer
OVERALL PROJECT SUMMARY IDENTIFYING METABOLIC VULNERABILITIES IN LUNG CANCER Lung Cancer is the most common cause of cancer deaths world-wide. Tyrosine kinase inhibitors and immuno...
Project 1
PROJECT 1 SUMMARY IDENTIFYING METABOLIC VULNERABILITIES REGULATED BY THE P53 FAMILY IN LUNG CANCER p53 is commonly mutated in all subtypes of human lung cancer. p53 is part of a fa...
Project 1
PROJECT 1 SUMMARY IDENTIFYING METABOLIC VULNERABILITIES REGULATED BY THE P53 FAMILY IN LUNG CANCER p53 is commonly mutated in all subtypes of human lung cancer. p53 is part of a fa...
Project 2
PROJECT 2 SUMMARY INVESTIGATING CYSTEINE ESSENTIALITY IN LUNG CANCER Cancer cells accumulate significant intracellular cysteine due to increased cystine uptake and loss of homeosta...
Identifying Metabolic Vulnerabilities in Lung Cancer
OVERALL PROJECT SUMMARY IDENTIFYING METABOLIC VULNERABILITIES IN LUNG CANCER Lung Cancer is the most common cause of cancer deaths world-wide.Tyrosine kinase inhibitors and immunot...
Project 2
PROJECT 2 SUMMARY INVESTIGATING CYSTEINE ESSENTIALITY IN LUNG CANCER Cancer cells accumulate significant intracellular cysteine due to increased cystine uptake and loss of homeosta...
Project 3
PROJECT 3 SUMMARY ROLES AND MECHANISMS OF ACTION OF METABOLIC VULNERABILITIES OF SCLC Small cell lung cancer (SCLC) lacks targeted therapies, and with only 7% overall survival on s...
Project 1
PROJECT 1 SUMMARY IDENTIFYING METABOLIC VULNERABILITIES REGULATED BY THE P53 FAMILY IN LUNG CANCER p53 is commonly mutated in all subtypes of human lung cancer. p53 is part of a fa...
Project 2
PROJECT 2 SUMMARY INVESTIGATING CYSTEINE ESSENTIALITY IN LUNG CANCER Cancer cells accumulate significant intracellular cysteine due to increased cystine uptake and loss of homeosta...
Project 3
PROJECT 3 SUMMARY ROLES AND MECHANISMS OF ACTION OF METABOLIC VULNERABILITIES OF SCLC Small cell lung cancer (SCLC) lacks targeted therapies, and with only 7% overall survival on s...
Project 4
PROJECT 4 SUMMARY: METABOLIC AND FUNCTIONAL REPROGRAMMING OF IMMUNOSUPPRESSIVE MYELOPOIESIS IN LUNG TUMORS Lung cancer cells and tumor-infiltrating immune subsets activate an integ...