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20,252 grants found
Showing 16,121 – 16,140 of 20,252 grants
Imaging the multifaceted response to a bispecific antibody therapy
Project Summary Resistance to the standard of care treatments contributes to mortality in patients with metastatic triple negative breast cancer (TNBC) or non-small cell lung cance...
Decision Support Training for Advanced Cancer Family Caregivers: The CASCADE Factorial Trial
Project Summary/Abstract A priority in oncology and palliative care is preparing the 3.2 million U.S. family caregivers of persons with cancer to effectively support patients in he...
Multilevel Interventions to Increase Adherence to Lung Cancer Screening
ABSTRACT Screening for lung cancer has the potential for a profound public health benefit.Lung cancer is the leading cause of US cancer morbidity and mortality for both men and wom...
The Role of YY1 in Castration-Resistant Prostate Cancer
PROJECT SUMMARY/ABSTRACT Standard treatment of prostate cancer with current agents fails due to development of therapy resistance and castration-resistant prostate cancer (CRPC), a...
Understanding the Contribution of Colorectal Cancer Tumor Characteristics to Disparities in Colorectal Cancer Survival
PROJECT ABSTRACT Colorectal cancer (CRC) is the second leading cause of cancer death among U.S. men and women.Racial disparities in CRC survival exist, where the CRC mortality rate...
A non-canonical role for EZH2 in rRNA methtlation
Background: Mounting evidence suggests that dysregulated epigenetic modifications play a crucial role in cancer initiation, progression, and metastasis.Epigenetic regulations inclu...
DNA Damage and Repair Mechanisms, Obesity, and Breast Cancer Disparities
In this collaborative study, we will investigate obesity-associated DNA damage and repair mechanisms as drivers of mortality disparities between Non-Hispanic Black (NHB) and White...
Optimizing Lung Cancer Screening in Cancer Survivors
The goal of the proposal is to identify optimal lung cancer (LC) screening strategies for breast (BC), prostate (PC), colorectal (CRC) cancer survivors.We will accomplish these goa...
Assessing the long-term impacts of the COVID-19 pandemic on disparities in cancer screening and follow-up
PROJECT SUMMARY/ABSTRACT: The COVID-19 pandemic has led to dramatic reductions in cancer screening and follow-up services.During the early months of the pandemic, national organiza...
SURVEILLANCE, EPIDEMIOLOGY, AND END RESULTS (SEER) PROGRAM-RESEARCH SUPPORT ONLY, PROGRAMMATIC MEETING
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
Evaluation of Orthogonally Oriented Electromagnetic Fields to Stabilize ROS, Induce DNA damage and Improve Survival in Non-Small Cell Lung Cancer
Project Summary / Abstract Non-small cell lung cancer (NSCLC) is one of the most common causes of cancer death in the USA and despite recent advances, the overall 5-year survival r...
Improving cancer health equity by targeting physician networks
PROJECT SUMMARY Disparities in outcomes among cancer patients who are rural-residing, with lower SES, and a racial minority are well-documented and have garnered significant nation...
Effectiveness and Mechanisms of Multilevel Implementation Strategies to Improve Provider Recommendation and Advance HPV Vaccination: a Cluster Randomized Trial
Project Abstract Millions of US teens remain at risk of developing human papillomavirus (HPV)-related cancers due to inadequate HPV vaccine uptake, despite strong endorsement in cl...
Imaging the multifaceted response to a bispecific antibody therapy
Project Summary Resistance to the standard of care treatments contributes to mortality in patients with metastatic triple negative breast cancer (TNBC) or non-small cell lung cance...
Decision Support Training for Advanced Cancer Family Caregivers: The CASCADE Factorial Trial
Project Summary/Abstract A priority in oncology and palliative care is preparing the 3.2 million U.S. family caregivers of persons with cancer to effectively support patients in he...
Multilevel Interventions to Increase Adherence to Lung Cancer Screening
ABSTRACT Screening for lung cancer has the potential for a profound public health benefit. Lung cancer is the leading cause of US cancer morbidity and mortality for both men and wo...
Optimizing Lung Cancer Screening in Cancer Survivors
The goal of the proposal is to identify optimal lung cancer (LC) screening strategies for breast (BC), prostate (PC), colorectal (CRC) cancer survivors. We will accomplish these go...
Improving cancer health equity by targeting physician networks
PROJECT SUMMARY Disparities in outcomes among cancer patients who are rural-residing, with lower SES, and a racial minority are well-documented and have garnered significant nation...
Lipid Metabolism in Liver Cancer
Project Summary Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related death worldwide, with 5- year survival less than 12%. Paralleling the increased inc...
DNA Damage and Repair Mechanisms, Obesity, and Breast Cancer Disparities
In this collaborative study, we will investigate obesity-associated DNA damage and repair mechanisms as drivers of mortality disparities between Non-Hispanic Black (NHB) and White...