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Showing 1,3011,320 of 20,252 grants

Completed OTHERS
MATCHMAKERS: SOLVING TCR RECOGNITION AND DESIGN VIA INTEGRATED HIGH-THROUGHPUT SCREENING, STRUCTURAL, FUNCTIONAL, AND COMPUTATIONAL APPROACHES
NATIONAL CANCER INSTITUTE Stanford University United States 2024 – 2025

Abstract Understanding how T cell receptors (TCRs) see tumor antigens presented by MHCs is necessary to fully understand how the immune system recognizes tumor antigens, and to rea...

$2.14M
USD
Completed OTHERS
MATCHMAKERS
NATIONAL CANCER INSTITUTE University of Washington United States 2024 – 2025

Abstract Understanding how T cell receptors (TCRs) see tumor antigens presented by MHCs is necessary to fully understand how the immune system recognizes tumor antigens, and to rea...

$3.27M
USD
Completed OTHERS
PROSPECT: Pathways, Risk factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
NATIONAL CANCER INSTITUTE King's College London United Kingdom 2024 – 2025

ABSTRACT Our vision is to unravel and ultimately reverse the intricate network of causal factors throughout the life course that disrupts biological homeostasis to promote colorect...

$3.33M
USD
Completed OTHERS
PROTECT - Harnessing PROTEin degradation for Advanced Childhood Tumors
NATIONAL CANCER INSTITUTE Prinses Maxima Voor Kinderoncologie, Bv Netherlands 2024 – 2025

ABSTRACT Title: PROTECT – Harnessing PROTEin degradation for Advanced Childhood Tumors Background Survival rates for children with solid tumors, including brain, have largely plate...

$866.2K
USD
Completed OTHERS
MATCHMAKERS - Solving T-cell receptor recognition and design via integrated high-throughput screening and structural, functional and computational approaches
NATIONAL CANCER INSTITUTE University of California, San Francisco United States 2024 – 2025

ABSTRACT: UCSF Understanding how T cell receptors (TCRs) see tumor antigens presented by MHCs is necessary to fully understand how the immune system recognizes tumor antigens, and...

$1.6M
USD
Completed OTHERS
C07 - Societal, Ancestry, Molecular and Biological Analyses of Inequalities: SAMBAI
NATIONAL CANCER INSTITUTE King's College London United Kingdom 2024 – 2025

SAMBAI: Societal, Ancestry, Molecular and Biological Analyses of Inequalities Research Abstract Background Prostate, breast, and pancreatic cancers all have a disproportionately hi...

$996.7K
USD
Completed OTHERS
MATCHMAKERS - Creating and training AI tools for TCR binding prediction and design
NATIONAL CANCER INSTITUTE Massachusetts Institute of Technology United States 2024 – 2025

Abstract Understanding how T cell receptors (TCRs) see tumor antigens presented by MHCs is necessary to fully understand how the immune system recognizes tumor antigens, and to rea...

$6.81M
USD
Completed OTHERS
MATCHMAKERS: Solving T-cell receptor recognition and design via integrated high-throughput screening and structural, functional and computational approaches
NATIONAL CANCER INSTITUTE Brigham and Women'S Hospital United States 2024 – 2025

Abstract Understanding how T cell receptors (TCRs) see tumor antigens presented by MHCs is necessary to fully understand how the immune system recognizes tumor antigens, and to rea...

$2.89M
USD
Completed OTHERS
SAMBAI: Societal, Ancestry, Molecular and Biological Analyses of Inequalities - University of Glasgow
NATIONAL CANCER INSTITUTE University of Glasgow United Kingdom 2024 – 2025

SAMBAI: Societal, Ancestry, Molecular and Biological Analyses of Inequalities Research Abstract Background Prostate, breast, and pancreatic cancers all have a disproportionately hi...

$560.2K
USD
Completed OTHERS
PROTECT (Harnessing PROTEin degradation for Advanced Childhood Tumors)
NATIONAL CANCER INSTITUTE University College London United Kingdom 2024 – 2025

ABSTRACT Background Survival rates for children with solid tumors, including brain, have largely plateaued over the past three decades making them the most common cause of disease-...

$1M
USD
Completed OTHERS
SAMBAI: SOCIETAL, ANCESTRY, MOLECULAR AND BIOLOGICAL ANALYSES OF INEQUALITIES (CGC)
NATIONAL CANCER INSTITUTE European Molecular Biology Laboratory Germany 2024 – 2025

SAMBAI: Societal, Ancestry, Molecular and Biological Analyses of Inequalities Research Abstract Background Prostate, breast, and pancreatic cancers all have a disproportionately hi...

$2.01M
USD
Completed OTHERS
PROTECT - Harnessing PROTEin Degradation for Advanced Childhood Tumours
NATIONAL CANCER INSTITUTE German Cancer Research Center Germany 2024 – 2025

Title: PROTECT – Harnessing PROTEin degradation for Advanced Childhood Tumors Abstract: Background Survival rates for children with solid tumors, including brain, have largely plat...

$5.07M
USD
Completed OTHERS
SAMBAI: Societal, Ancestry and Molecular Biology Analyses of Inequalities
NATIONAL CANCER INSTITUTE New York University School of Medicine United States 2024 – 2025

SAMBAI: Societal, Ancestry, Molecular and Biological Analyses of Inequalities Research Abstract Background Prostate, breast, and pancreatic cancers all have a disproportionately hi...

$1.08M
USD
Completed OTHERS
PROSPECT - Stem cell models
NATIONAL CANCER INSTITUTE Massachusetts Institute of Technology United States 2024 – 2025

ABSTRACT Our vision is to unravel and ultimately reverse the intricate network of causal factors throughout the life course that disrupts biological homeostasis to promote colorect...

$3.44M
USD
Completed OTHERS
SAMBAI - Bridging Research Investigations of cancer Disparities and Global Equity (BRIDGE)
NATIONAL CANCER INSTITUTE Emory University United States 2024 – 2025

SAMBAI - Bridging Research Investigations of cancer Disparities and Global Equity (BRIDGE) Research Abstract Background Prostate, breast, and pancreatic cancers all have a dispropo...

$3.16M
USD
Completed OTHERS
PROTECT (Harnessing PROTEin degradation for Advanced Childhood Tumors)
NATIONAL CANCER INSTITUTE Dana-Farber Cancer Inst United States 2024 – 2025

Abstract: Background Survival rates for children with solid tumors, including brain, have largely plateaued over the past three decades making them the most common cause of disease...

$13.56M
USD
Completed OTHERS
SAMBAI - Establishing a comprehensive assessment of contributors to cancer inequities across the African diaspora
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2024 – 2025

SAMBAI: Societal, Ancestry, Molecular and Biological Analyses of Inequalities Research Abstract Background Prostate, breast, and pancreatic cancers all have a disproportionately hi...

$1.42M
USD
Completed OTHERS
CANCER GRAND CHALLENGES 2024 SOCIETAL, ANCESTRY, MOLECULAR AND BIOLOGICAL ANALYSES OF INEQUALITIES (SAMBAI) Morehouse School of Medicine
NATIONAL CANCER INSTITUTE Morehouse School of Medicine United States 2024 – 2025

SAMBAI: Societal, Ancestry, Molecular and Biological Analyses of Inequalities Research Abstract Background Prostate, breast, and pancreatic cancers all have a disproportionately hi...

$6.14M
USD
Completed OTHERS
MATCHMAKERS - Solving TCR recognition and design via integrated high-throughput screening, structural, functional, and computational approaches
NATIONAL CANCER INSTITUTE Children'S Hosp of Philadelphia United States 2024 – 2025

Abstract Understanding how T cell receptors (TCRs) see tumor antigens presented by MHCs is necessary to fully understand how the immune system recognizes tumor antigens, and to rea...

$2.48M
USD
Completed OTHERS
PROSPECT-Global Consortium and Risk Factor Discovery
NATIONAL CANCER INSTITUTE Washington University United States 2024 – 2025

ABSTRACT Our vision is to unravel and ultimately reverse the intricate network of causal factors throughout the life course that disrupts biological homeostasis to promote colorect...

$7.88M
USD