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Showing 81100 of 20,252 grants

Active NON-SBIR/STTR RPGS
A 3D DCE-US Interconnected Voxel Analysis Framework for Bedside Characterization of Tumor Vascular Properties in Liver Malignancies.
NATIONAL CANCER INSTITUTE University of California, San Diego United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT Tumor vascular networks are highly abnormal and complex, vary significantly by tumor type and on a patient- by-patient basis. More importantly, patient-spe...

$5.99M
USD
Completed SBIR/STTR CONTRACTS
PHASE I AWARD - AN ORGAN-ON-VASCULARNET MODEL FOR IN VITRO EVALUATION OF RADIATION AND DRUG THERAPIES
NATIONAL CANCER INSTITUTE Chromologic, Llc United States 2024 – 2025

There is an urgent need for near physiological organ-on-chip models that can replace testing in animals for human drug development.The Organ-on-VascularNet platform is a 3D organoi...

$4M
USD
Completed SBIR/STTR CONTRACTS
Topic 464 Phase I Award: Network-Based Multimodal Data Analysis Cloud Software for Cancer Biomarker Discovery and Drug Development
NATIONAL CANCER INSTITUTE Sostos Llc United States 2024 – 2025

Sostos LLC will deliver cloud-based multimodal data analysis software enabling users to discover biomarkers and develop new/repositioning drugs to improve cancer outcomes.Current m...

$4M
USD
Active SBIR/STTR CONTRACTS
FY24 SBIR Phase 2 RD Contract - Topic 431 Light Research, Inc.
NATIONAL CANCER INSTITUTE Light Research, Inc United States 2024 – 2026

Oral and oropharyngeal squamous cell carcinoma (OSCC), ranking as the sixth most prevalent cancer globally, is especially prevalent in low- and middle-income countries (LMICs).The...

$19.99M
USD
Completed NON SBIR/STTR CONTRACTS
TOXICOLOGY STUDIES IN RATS AND DOGS ADMINISTERED AIT-102
NATIONAL CANCER INSTITUTE Iit Research Institute United States 2024 – 2025

The objective of this task order is to conduct toxicology studies in rats and dogs administered AIT-102 to support preclinical research.Any target organ toxicity seen in animals th...

$5.68M
USD
Active SBIR/STTR CONTRACTS
FY24 SBIR PHASE IITOPIC NO. 434PROJECT TITLE: NOVEL NIST TRACEABLE IONIZATION CHAMBER FOR FLASH DOSIMETRY
NATIONAL CANCER INSTITUTE Standard Imaging, Inc United States 2024 – 2026

One of the major factors limiting pre-clinical and clinical use of FLASH RT is the difficulty in measuring FLASH irradiation beam parameters such as dose, dose per pulse, pulse rep...

$12.22M
USD
Completed SBIR/STTR CONTRACTS
SBIR Topic 463: Clinical evaluation for early detection of esophageal cancer with a novel fluorescence endoscope and pegulicianine, a novel fluorescent probe
NATIONAL CANCER INSTITUTE Lumicell, Inc United States 2024 – 2025

The incidence of esophageal adenocarcinoma (EAC) is rising more rapidly in the U.S. than any other malignancy, increasing over 350% in the past decades. Most cases of EAC are prece...

$3.99M
USD
Completed SBIR/STTR CONTRACTS
TOPIC 464: CLOUD-BASED MULTIMODAL DATA ANALYSIS SOFTWARE FOR THE CANCER RESEARCH DATA COMMONS
NATIONAL CANCER INSTITUTE Anaconda, Inc United States 2024 – 2025

Cancer research data comes in a bewildering variety of data types, formats, spatial scales, and modalities, while new techniques are making ever-larger datasets available.Making se...

$4M
USD
Completed NON SBIR/STTR CONTRACTS
Contract Orientation & Kickoff Meeting for PREVENT Cancer Preclinical Drug Development Program: CGMP Pool
NATIONAL CANCER INSTITUTE Unknown United States 2024 – 2024

The NCI PREVENT Cancer Preclinical Drug Development Program (PREVENT) was initially launched in 2012 to provide extramural research community with structured research support resou...

$35K
USD
Active SBIR/STTR CONTRACTS
ISYSMET: AI-POWERED PLATFORM FOR INTEGRATIVE ANALYSIS OFMULTIMODAL DATA
NATIONAL CANCER INSTITUTE Omicscraft, Llc United States 2024 – 2026

Recent advances in cloud-based resources and technologies for imaging and multi-omics analysis have created new opportunities for exploring relationships between medical images, mo...

$20M
USD
Active SBIR/STTR CONTRACTS
2024 SBIR TOPIC 465: CANCER PREVENTION AND TREATMENT CLINICAL TRIALS TOOLS FOR RECRUITMENT AND RETENTION OF DIVERSE POPULATIONS
NATIONAL CANCER INSTITUTE Mednet, Inc United States 2024 – 2026

TheMednet, an interactive Q&A and social decision support platform, is currently the largest and most active online community for oncologists in the United States, reaching ove...

$20M
USD
Active SBIR/STTR CONTRACTS
ONTRIAL: AI-DRIVEN AND EMR INTEGRATED CLINICAL TRIAL RECRUITMENT TOOL USED BY CLINICAL TRIAL AND PROVIDER TEAMS FOR RECRUITMENT OF DIVERSE POPULATIONS.
NATIONAL CANCER INSTITUTE Vizlitics Inc United States 2024 – 2026

Lags, delays, and failures in clinical trial recruitment and enrollment hampers the rate of drug development and medical progress. The work proposed in this contract submission add...

$20.5M
USD
Active NON-SBIR/STTR RPGS
Improving measurement of cancer registry completeness
NATIONAL CANCER INSTITUTE Emory University United States 2024 – 2029

PROJECT SUMMARY Surveillance for cancer incidence and mortality is crucial to cancer control and cancer research. Cancer registries are the basis for allocating public health resou...

$6.54M
USD
Active NON-SBIR/STTR RPGS
Understanding Integration in Oncology Care and Association with Quality and Outcomes
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Overall Program Project This Program Project seeks to understand features of care integration in oncology that are associated with higher-quality care del...

$22.83M
USD
Active NON-SBIR/STTR RPGS
Administrative Core
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

ADMINISTRATIVE CORE PROJECT SUMMARY/ABSTRACT The Administrative Core provides coordination and administrative oversight for the Program Project, “Understanding Integration in Oncol...

Active NON-SBIR/STTR RPGS
Project 1: Care Integration for Patients with Cancer Treated in Health Systems
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Project 1 - Care Integration for Patients with Cancer Treated in Health Systems This Project focuses on care integration for patients with cancer who are...

Active NON-SBIR/STTR RPGS
Project 2: Care Integration for Patients with Cancer Treated in Independent Practices
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Project 2 - Care Integration for Patients with Cancer Treated in Independent Practices The goal of this Project is to describe care integration for patien...

Active NON-SBIR/STTR RPGS
Project 3: Care Integration for Patients with Cancer Receiving Post-Acute Care and Hospice
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Project 3 - Care Integration for Patients Receiving Post-Acute Care and Hospice This Project focuses on care integration for patients with cancer who are...

Active NON-SBIR/STTR RPGS
Project 4: Care Integration for Patients with Cancer Using Specialty Pharmacies
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Project 4 - Care Integration for Patients with Cancer Using Specialty Pharmacies This project aims to examine the integration of specialty pharmacies into...

Active NON-SBIR/STTR RPGS
Statistical Methods and Data Core
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Statistical Methods and Data Core The Statistical Methods and Data Core will provide technical expertise in data and analysis and develop new methods to d...