Browse All Grants
20,252 grants found
Showing 4,021 – 4,040 of 20,252 grants
Administrative Core
PROJECT SUMMARY / ABSTRACT – ADMINISTRATIVE CORE The Administrative Core (AC) will provide organizational infrastructure for Virginia Commonwealth University - Massey Cancer Center...
PDX Core
PROJECT SUMMARY / ABSTRACT U4HELPP PDX CORE A profound limitation to personalized approaches for therapeutic development in cancer is the lack of relevant patient derived models in...
Bioinformatics Core
Project Summary/Abstract The primary goal of the Bioinformatics Core of VCU’s U4HELPP is to provide data management, quality control, reproducible analyses, data storage, and data...
Research Project 1 PDAC Molecular Subtypes Contribute to Cancer Health Disparities
PROJECT SUMMARY Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease that is refractory to current treatment strategies due in part to adaptive mechanisms of chemoresistance...
Targeting Menin Protein Stability In AML
PROJECT SUMMARY Multiple Endocrine Neoplasia Type 1 (MEN1/MENIN) is a transcriptional regulator known to interact with Lysine Methyltransferase 2A (KMT2A/MLL1) driving aggressive s...
Mechanism of Lupus La:miR-122 ribonucleoprotein sorting into breast cancer-derived exosomes
PROJECT SUMMARY / ABSTRACT Extracellular vesicles (EVs) comprise a heterogeneous pool of membrane-enclosed compartments secreted to the extracellular milieu of cells. Eukaryotic ce...
Targeting Menin Protein Stability In AML
PROJECT SUMMARY Multiple Endocrine Neoplasia Type 1 (MEN1/MENIN) is a transcriptional regulator known to interact with Lysine Methyltransferase 2A (KMT2A/MLL1) driving aggressive s...
Mechanism of Lupus La:miR-122 ribonucleoprotein sorting into breast cancer-derived exosomes
PROJECT SUMMARY / ABSTRACT Extracellular vesicles (EVs) comprise a heterogeneous pool of membrane-enclosed compartments secreted to the extracellular milieu of cells. Eukaryotic ce...
Bispecific Antibody Maintenance Therapy after Allogeneic Bone Marrow Transplant
Project Summary Dr. Jonathan Webster is an Assistant Professor of Oncology in the Division of Hematologic Malignancies at The Johns Hopkins University School of Medicine. He is a m...
DNA evaluation of fragments for early interception (DELFI) of Lung cancer
Project Summary Cell-free DNA in the blood provides a non-invasive diagnostic avenue for patients with cancer. Our groups have pioneered liquid biopsy approaches for detection and...
TCI Mentored Medical Student Summer Scholars (TCI-MMSSS) Program
The goal of our Tisch Cancer Institute (TCI) Mentored Medical Student Summer Scholars (TCI-MMSSS) Program is to inspire medical students to pursue careers in cancer research throug...
Dual targeting of cGAS-STING and splicing to prime lung cancer immunogenicity
Project Summary Lung cancer is the leading cause of cancer-related death in the United States. Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and despite...
Chemical Biology-Based Tools to Uncover the Function of PARP16 in cancer
PROJECT SUMMARY/ABSTRACT PARP16, a member of the PARP family of enzymes responsible for carrying out the post-translational modification known as ADP-ribosylating, is emerging as a...
Bispecific Antibody Maintenance Therapy after Allogeneic Bone Marrow Transplant
Project Summary Dr. Jonathan Webster is an Assistant Professor of Oncology in the Division of Hematologic Malignancies at The Johns Hopkins University School of Medicine. He is a m...
TCI Mentored Medical Student Summer Scholars (TCI-MMSSS) Program
The goal of our Tisch Cancer Institute (TCI) Mentored Medical Student Summer Scholars (TCI-MMSSS) Program is to inspire medical students to pursue careers in cancer research throug...
DNA evaluation of fragments for early interception (DELFI) of Lung cancer
Project Summary Cell-free DNA in the blood provides a non-invasive diagnostic avenue for patients with cancer. Our groups have pioneered liquid biopsy approaches for detection and...
Dual targeting of cGAS-STING and splicing to prime lung cancer immunogenicity
Project Summary Lung cancer is the leading cause of cancer-related death in the United States. Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and despite...
Chemical Biology-Based Tools to Uncover the Function of PARP16 in cancer
PROJECT SUMMARY/ABSTRACT PARP16, a member of the PARP family of enzymes responsible for carrying out the post-translational modification known as ADP-ribosylating, is emerging as a...
The impact of sepsis-induced inflammation on pancreatic cancer liver metastasis
1 PROJECT SUMMARY 2 Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic malignancy and the third-leading cause of 3 cancer-related death in adults. A majority of patient...
The impact of sepsis-induced inflammation on pancreatic cancer liver metastasis
1 PROJECT SUMMARY 2 Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic malignancy and the third-leading cause of 3 cancer-related death in adults. A majority of patient...