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20,252 grants found
Showing 3,521 – 3,540 of 20,252 grants
Implementing and Evaluating the Cancer Tracking System (CATSystem): A systems level intervention to improve Cervical Cancer screening, treatment referral and follow up in Kenya
Abstract In Kenya, cervical cancer (CC) contributes to over 80% of female reproductive-tract cancers,4 yet only 16.4% of eligible women are screened for CC.5 This is far below the...
Reflectance confocal microscopy-optical coherence tomography (RCM-OCT) imaging of oral lesions: Toward an affordable device and approach for developing countries
High rates of incidence and prevalence of oral cancers occur in 15-20 developing low-and-middle income countries (LMICs) in Asia and Africa. Visual clinical examination followed by...
Targeting fibrosis to change cancer outcomes
PROJECT SUMMARY Scleroderma (SSc) patients have more than a 300% increased risk of lung cancer, or Cancerous Scleroderma (CSc). SSc is a chronic autoimmune connective tissue diseas...
Metabolic vulnerabilities in cancers with impaired TCA cycle activity
PROJECT SUMMARY Cancer cells exploit multiple metabolic strategies to generate biosynthetic precursors that fuel malignant proliferation. Such metabolic redundancy and plasticity h...
Research Specialist in Cancer Genomics to Integrate Basic Research and Clinical Data
ABSTRACT Human cancers are complex diseases with pathobiology driven by heritable genetics, environmental exposures, somatic genomic and epigenomic alterations, and contributions f...
Implementing and Evaluating the Cancer Tracking System (CATSystem): A systems level intervention to improve Cervical Cancer screening, treatment referral and follow up in Kenya
Abstract In Kenya, cervical cancer (CC) contributes to over 80% of female reproductive-tract cancers,4 yet only 16.4% of eligible women are screened for CC.5 This is far below the...
Role of LSD1 in Triple Negative Breast Cancer Development and Therapeutic Response
PROJECT SUMMARY/ABSTRACT Breast cancer (BC) is the most common cancer and the second leading cause of cancer death in American women. About 10-20% of breast cancers are triple-nega...
AUTOMATED DEIDENTIFICATION OF PATHOLOGY AND RADIOLOGY DATA
The overall project objective is to optimize and automate the detection and redaction of PHI in radiology data (DICOM) and pathology data (Whole Slide Imaging - WSI) – both header...
NCI SBIR Contract Topic 428 Phase II (Solicitation Number: BAA 75N91022R00027): Cloud-based Liquid-biopsy and Radiomics Platform for the Cancer Research Data Commons
Integrative analysis of multi-omics datasets is revolutionizing cancer research and patient care.To take advantage of the full breadth of CRDC’s petabyte-scale data, EarlyDx will s...
TOPIC 454 - SOFTWARE TO EVALUATE ARTIFICIAL INTELLIGENCE/MACHINE LEARNING MEDICAL DEVICES IN ONCOLOGY SETTINGS
Supervised, Machine Learning based oncologic AI algorithms degrade over time and don’t generalize well. The FDA requires the conduct of standalone testing of radiologic, AI product...
Multi-Modality Imaging-Based Quantitative Pre/During/Post-Treatment Lymph Node Monitoring in Cancers
The correct determination of nodal metastatic disease is imperative for patient management in oncology, since the patient’s prognosis and subsequent treatment are inherently linked...
SERVICES TO EXTEND METHODS FOR RISK PREDICTION WITH A CONTINUOUS TIME MODEL FOR SURVIVAL UNDER COMPETING RISKS
THIS PURCHASE ORDER INCLUDES SERVICES TO EXTEND METHODS FOR RISK PREDICTION WITH A CONTINUOUS TIME MODEL FOR SURVIVAL UNDER COMPETING RISKS USING TWO-TIME SCALES
Role of LSD1 in Triple Negative Breast Cancer Development and Therapeutic Response
PROJECT SUMMARY/ABSTRACT Breast cancer (BC) is the most common cancer and the second leading cause of cancer death in American women. About 10-20% of breast cancers are triple-nega...
Development of abuse liability-based tobacco tax proposals: Experimental impact on tobacco-related socioeconomic cancer health disparities
PROJECT SUMMARY/ABSTRACT Nearly 30% of all cancer deaths are attributable to tobacco use. Tobacco taxes have positively impacted the prevalence of tobacco use and subsequently the...
A novel AR degrader in castrate-resistant prostate cancer
Androgen receptor (AR) plays a critical role in prostate cancer (PCa) in all stages. While a majority of patients with PCa initially respond to androgen deprivation and/or anti-and...
Engineered Nanoformulation for Immune-modulation in Cancer
Expression of immune check point (ICP) molecules on tumor cells and the host immune cells, especially T-cells present in the tumor milieu, negatively impact the cancer treatment ou...
Metabolic vulnerabilities in cancers with impaired TCA cycle activity
PROJECT SUMMARY Cancer cells exploit multiple metabolic strategies to generate biosynthetic precursors that fuel malignant proliferation. Such metabolic redundancy and plasticity h...
Multi-Modality Imaging-Based Quantitative Pre/During/Post-Treatment Lymph Node Monitoring in Cancers
The correct determination of nodal metastatic disease is imperative for patient management in oncology, since the patient’s prognosis and subsequent treatment are inherently linked...
Role of LSD1 in Triple Negative Breast Cancer Development and Therapeutic Response
PROJECT SUMMARY/ABSTRACT About 10-20% of breast cancers are triple-negative breast cancers (TNBC), which have a poorer prognosis and worse clinical outcome than other types of BC....
Targeting fibrosis to change cancer outcomes
PROJECT SUMMARY Scleroderma (SSc) patients have more than a 300% increased risk of lung cancer, or Cancerous Scleroderma (CSc). SSc is a chronic autoimmune connective tissue diseas...